1693-250   Simvastatin   品牌 Biovision

Simvastatin

货号: 1693-250      产品名称: Simvastatin   品牌: Biovision 规格: 250 mg 3周到货 生化实验

Simvastatin
Product Overview
Product Name: Simvastatin
Alternate Name/Synonyms: MK-733; Synvinolin
Description: A synthetic analog of Lovastatin (Cat. No. 1692-50, 250). Cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase. Inhibits the biosynthesis of isoprenoids and prevents small G protein activation.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 79902-63-9
Molecular Formula: C₂₅H₃₈O₅
Molecular Weight: 418.57
Purity: ≥98% by HPLC
Solubility:DMSO (25 mg/ml) or Ethanol (30 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
InChi: InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChi Key: RYMZZMVNJRMUDD-HGQWONQESA-N
PubChem CID: 54454
MDL Number: MFCD00072007
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

1693-50   Simvastatin   品牌 Biovision

Simvastatin

货号: 1693-50      产品名称: Simvastatin   品牌: Biovision 规格: 50 mg 3周到货 生化实验

Simvastatin
Product Overview
Product Name: Simvastatin
Alternate Name/Synonyms: MK-733; Synvinolin
Description: A synthetic analog of Lovastatin (Cat. No. 1692-50, 250). Cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase. Inhibits the biosynthesis of isoprenoids and prevents small G protein activation.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 79902-63-9
Molecular Formula: C₂₅H₃₈O₅
Molecular Weight: 418.57
Purity: ≥98% by HPLC
Solubility:DMSO (25 mg/ml) or Ethanol (30 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C
InChi: InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
InChi Key: RYMZZMVNJRMUDD-HGQWONQESA-N
PubChem CID: 54454
MDL Number: MFCD00072007
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

S3449-10 mg   Simvastatin   品牌 LKT

Simvastatin

货号: S3449-10 mg      产品名称: Simvastatin   品牌: LKT 规格: 10 mg 三周到货 生化试验

Simvastatin      
Description
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits cell proliferation of human glioma cells and of acute myeloid leukemia cells. Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors.
Specifications 
Cas No. 79902-63-9
Product ID  S3449
Product Name  Simvastatin
Chemical Name  2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
Synonym Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord
Formula Wt. 418.57
Melting Point 135-138 oC
Purity 97% 
Solubility (mg/ml) DMSO 540; ethanol 160; methanol 200; water 0.03.
Store Temp Ambient
Ship Temp Ambient
References Inano H. Suzuki K. Onoda M. Wakabayashi K. Carcinogenesis. 18:1723-7 (1997). Kikuchi T. Nagata Y. Abe T. J Neurooncol. 34:233-9 (1997). Lishner M. Bar-Sef A. Elis A. Fabian I. J Investig Med. 49:319-24 (2001). Mol, M.J.et al Lancet 2:936 (198
 

室温

S3449-25 mg   Simvastatin   品牌 LKT

Simvastatin

货号: S3449-25 mg      产品名称: Simvastatin   品牌: LKT 规格: 25 mg 三周到货 生化试验

Simvastatin
Description
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits cell proliferation of human glioma cells and of acute myeloid leukemia cells. Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors.
Specifications 
Cas No. 79902-63-9
Product ID  S3449
Product Name  Simvastatin
Chemical Name  2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
Synonym Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord
Formula Wt. 418.57
Melting Point 135-138 oC
Purity 97% 
Solubility (mg/ml) DMSO 540; ethanol 160; methanol 200; water 0.03.
Store Temp Ambient
Ship Temp Ambient
References Inano H. Suzuki K. Onoda M. Wakabayashi K. Carcinogenesis. 18:1723-7 (1997). Kikuchi T. Nagata Y. Abe T. J Neurooncol. 34:233-9 (1997). Lishner M. Bar-Sef A. Elis A. Fabian I. J Investig Med. 49:319-24 (2001). Mol, M.J.et al Lancet 2:936 (198
 

室温

567021-50MG   Simvastatin, Sodium   品牌 Merck

Simvastatin, Sodium

货号: 567021-50MG      产品名称: Simvastatin, Sodium   品牌: Merck 规格: *** 3周到货 生化实验

Simvastatin, Sodium Salt
L-Type Calcium Channel Blocker VI
Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free preparations. Also available as a 10 mM solution in H2O (Cat. No. 567022).
产品信息
Form  Beige solid
Molar mass  458.6
Hygrocopic  是的
Packaged under inert gas  是的
Purity  ≥97% by HPLC
Solubility  DMSO, EtOH, or H
Chemical formula  C25H39O6 • Na
商店和运输信息
Storage  -20°C
Ship  Ambient Temperature Only
Standard Handling

-20°C

567022-5MG   InSolution Simvastatin, Sodium Salt   品牌 Merck

InSolution Simvastatin, Sodium Salt

货号: 567022-5MG      产品名称: InSolution Simvastatin, Sodium Salt   品牌: Merck 规格: *** 3周到货 生化实验

InSolution™ Simvastatin, Sodium Salt
L-Type Calcium Channel Blocker VI
Carboxylate form of Simvastatin (Cat. No. 567020) that is active in whole cells and in cell-free assays. A lipophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that blocks Ras function through inhibition of farnesylation. Also inhibits glucose-induced Ca2+-signaling and insulin secretion by blocking L-type Ca2+ channels in rat islet β-cells. Inhibits cell proliferation of human smooth muscle cells. The solid form of this compound (Cat. No. 567021) is also available.
产品信息
Form  Liquid
Formulation  A 10 mM (5 mg/1.09 ml) solution of Simvastatin, Sodium Salt (Cat. No. 567021) in H2O.
Molar mass  458.6
Protect from Light  是的
Avoid freeze/thaw  是的
Packaged under inert gas  是的
Cell permeable  是的
Reversible  是的
Purity  ≥95% by HPLC
Chemical formula  C25H39O6 •Na
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Irritant

≤ -70°C

S3449-100 mg   Simvastatin   品牌 LKT

Simvastatin

货号: S3449-100 mg      产品名称: Simvastatin   品牌: LKT 规格: 100 mg 三周到货 生化试验

Simvastatin      
Description
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits cell proliferation of human glioma cells and of acute myeloid leukemia cells. Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors.
Specifications 
Cas No. 79902-63-9
Product ID  S3449
Product Name  Simvastatin
Chemical Name  2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
Synonym Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord
Formula Wt. 418.57
Melting Point 135-138 oC
Purity 97% 
Solubility (mg/ml) DMSO 540; ethanol 160; methanol 200; water 0.03.
Store Temp Ambient
Ship Temp Ambient
References Inano H. Suzuki K. Onoda M. Wakabayashi K. Carcinogenesis. 18:1723-7 (1997). Kikuchi T. Nagata Y. Abe T. J Neurooncol. 34:233-9 (1997). Lishner M. Bar-Sef A. Elis A. Fabian I. J Investig Med. 49:319-24 (2001). Mol, M.J.et al Lancet 2:936 (198
 

室温

S3449-50 mg   Simvastatin   品牌 LKT

Simvastatin

货号: S3449-50 mg      产品名称: Simvastatin   品牌: LKT 规格: 50 mg 三周到货 生化试验

Simvastatin      
Description
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits cell proliferation of human glioma cells and of acute myeloid leukemia cells. Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors.
Specifications 
Cas No. 79902-63-9
Product ID  S3449
Product Name  Simvastatin
Chemical Name  2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
Synonym Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord
Formula Wt. 418.57
Melting Point 135-138 oC
Purity 97% 
Solubility (mg/ml) DMSO 540; ethanol 160; methanol 200; water 0.03.
Store Temp Ambient
Ship Temp Ambient
References Inano H. Suzuki K. Onoda M. Wakabayashi K. Carcinogenesis. 18:1723-7 (1997). Kikuchi T. Nagata Y. Abe T. J Neurooncol. 34:233-9 (1997). Lishner M. Bar-Sef A. Elis A. Fabian I. J Investig Med. 49:319-24 (2001). Mol, M.J.et al Lancet 2:936 (198
 

室温

S3449-500 mg   Simvastatin   品牌 LKT

Simvastatin

货号: S3449-500 mg      产品名称: Simvastatin   品牌: LKT 规格: 500 mg 三周到货 生化试验

Simvastatin      
Description
A potent HMG-CoA reductase inhibitor and hypocholesterolemic agent. Inhibits cell proliferation of human glioma cells and of acute myeloid leukemia cells. Anti-carcinogenic during the promotion phase of radiation-induced mammary tumors.
Specifications 
Cas No. 79902-63-9
Product ID  S3449
Product Name  Simvastatin
Chemical Name  2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
Synonym Synvinolin; MK-733; Denan; Liponorm; Lodales; Simovil; Sinvacor; Sivastin; Zocor; Zocord
Formula Wt. 418.57
Melting Point 135-138 oC
Purity 97% 
Solubility (mg/ml) DMSO 540; ethanol 160; methanol 200; water 0.03.
Store Temp Ambient
Ship Temp Ambient
References Inano H. Suzuki K. Onoda M. Wakabayashi K. Carcinogenesis. 18:1723-7 (1997). Kikuchi T. Nagata Y. Abe T. J Neurooncol. 34:233-9 (1997). Lishner M. Bar-Sef A. Elis A. Fabian I. J Investig Med. 49:319-24 (2001). Mol, M.J.et al Lancet 2:936 (198
 

室温

10010344-100   Simvastatin   品牌 Cayman

Simvastatin

货号: 10010344-100      产品名称: Simvastatin   品牌: Cayman 规格: 100 mg 3周

Simvastatin
Cayman Chemical Item Number 10010344
Description
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs.1↗ Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.12 nM for the hydrolyzed, open ring form of the molecule.2↗ Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe (Zetia) to treat dyslipidemia. This drug combination is known commercially as Vytorin™ or Inegy™. After 18 days of treatment with simvastatin in dogs at a dose of 8 mg/kg per day, plasma cholesterol levels were reduced by 33%.3↗ Simvastatin also suppresses TNF-induced NF-κB activation (IC50 ~ 13 µM), which potentiates apoptosis in human myeloid leukemia cells and thus may be useful in treating cancer.4↗
Synonyms MK 733
Formal Name 2,​2-​dimethyl-​1S,​2,​3R,​7S,​8S,​8aR-​hexahydro-​3,​7-​dimethyl-​8-​[2-​[(2R,​4R)-​tetrahydro-​4-​hydroxy-​6-​oxo-​2H-​pyran-​2-​yl]ethyl]-​1-​naphthalenyl ester,​ butanoic acid
CAS Number 79902-63-9
Molecular Formula C25H38O5
Formula Weight 418.6
Formulation A crystalline solid
Purity ≥98%
λmax 238 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES C[C@H]​1C=CC2=C[C@H]​(C)​C[C@H]​(OC(C(C)​(C)​CC)​=O)​C2[C@H]​1CC[C@@H]​3C[C@@H]​(O)​CC(O3)​=O 
InCHI Code ​1S/C25H38O5/c1-6-25(4,5)​24(28)​30-21-12-15(2)​11-17-8-7-16(3)​20(23(17)​21)​10-9-19-13-18(26)​14-22(27)​29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23/m0/s1 
InCHI Key RYMZZMVNJRMUDD-OVOOIQHOSA-N

-20°C

10010345-1   Simvastatin (sodium salt)   品牌 Cayman

Simvastatin (sodium salt)

货号: 10010345-1      产品名称: Simvastatin (sodium salt)   品牌: Cayman 规格: 1 mg 3周

Simvastatin (sodium salt)
Cayman Chemical Item Number 10010345
Description HMG-CoA reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs.1↗ Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.12 nM for the hydrolyzed, open ring form of the molecule.2↗ Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe (Zetia) to treat dyslipidemia. This drug combination is known commercially as Vytorin or Inegy. In dogs, after 18 days of treatment with simvastatin at a dose of 8 mg/kg per day, plasma cholesterol levels were reduced by 33%.3↗ Simvastatin also suppresses TNF-induced NF-κB activation (IC50 ~ 13 µM), which potentiates apoptosis in human myeloid leukemia cells and thus, may be useful in treating cancer.4↗
Synonyms Zocor™
Formal Name (βR,​δR,​1S,​2S,​6R,​8S,​8aR)-​8-​(2,​2-​dimethyl-​1-​oxobutoxy)-​1,​2,​6,​7,​8,​8a-​hexahydro-​β,​δ-​dihydroxy-​2,​6-​dimethyl-​1-​naphthaleneheptanoic acid,​ monosodium salt
CAS Number 101314-97-0
Molecular Formula C25H39O6 • Na
Formula Weight 458.6
Formulation A crystalline solid
Purity ≥98%
λmax 231, 238, 246 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES C[C@@H]​1C[C@H]​(OC(C(C)​(CC)​C)​=O)​C2C(C=C[C@H]​(C)​[C@@H]​2CC[C@@H]​(O)​C[C@@H]​(O)​CC([O-]​)​=O)​=C1.[Na]​ 
InCHI Code ​1S/C25H40O6.Na/c1-6-25(4,5)​24(30)​31-21-12-15(2)​11-17-8-7-16(3)​20(23(17)​21)​10-9-18(26)​13-19(27)​14-22(28)​29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)​;/p-1/t15-,16-,18+,19+,20-,21-,23;/m0./s1 
InCHI Key SVIXZYADIXSPPP-SBRLSJPESA-M

-20°C

10010345-5   Simvastatin (sodium salt)   品牌 Cayman

Simvastatin (sodium salt)

货号: 10010345-5      产品名称: Simvastatin (sodium salt)   品牌: Cayman 规格: 5 mg 3周

Simvastatin (sodium salt)
Cayman Chemical Item Number 10010345
Description HMG-CoA reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs.1↗ Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.12 nM for the hydrolyzed, open ring form of the molecule.2↗ Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe (Zetia) to treat dyslipidemia. This drug combination is known commercially as Vytorin or Inegy. In dogs, after 18 days of treatment with simvastatin at a dose of 8 mg/kg per day, plasma cholesterol levels were reduced by 33%.3↗ Simvastatin also suppresses TNF-induced NF-κB activation (IC50 ~ 13 µM), which potentiates apoptosis in human myeloid leukemia cells and thus, may be useful in treating cancer.4↗
Synonyms Zocor™
Formal Name (βR,​δR,​1S,​2S,​6R,​8S,​8aR)-​8-​(2,​2-​dimethyl-​1-​oxobutoxy)-​1,​2,​6,​7,​8,​8a-​hexahydro-​β,​δ-​dihydroxy-​2,​6-​dimethyl-​1-​naphthaleneheptanoic acid,​ monosodium salt
CAS Number 101314-97-0
Molecular Formula C25H39O6 • Na
Formula Weight 458.6
Formulation A crystalline solid
Purity ≥98%
λmax 231, 238, 246 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES C[C@@H]​1C[C@H]​(OC(C(C)​(CC)​C)​=O)​C2C(C=C[C@H]​(C)​[C@@H]​2CC[C@@H]​(O)​C[C@@H]​(O)​CC([O-]​)​=O)​=C1.[Na]​ 
InCHI Code ​1S/C25H40O6.Na/c1-6-25(4,5)​24(30)​31-21-12-15(2)​11-17-8-7-16(3)​20(23(17)​21)​10-9-18(26)​13-19(27)​14-22(28)​29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)​;/p-1/t15-,16-,18+,19+,20-,21-,23;/m0./s1 
InCHI Key SVIXZYADIXSPPP-SBRLSJPESA-M

-20°C

10010345-10   Simvastatin (sodium salt)   品牌 Cayman

Simvastatin (sodium salt)

货号: 10010345-10      产品名称: Simvastatin (sodium salt)   品牌: Cayman 规格: 10 mg 3周

Simvastatin (sodium salt)
Cayman Chemical Item Number 10010345
Description HMG-CoA reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs.1↗ Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.12 nM for the hydrolyzed, open ring form of the molecule.2↗ Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe (Zetia) to treat dyslipidemia. This drug combination is known commercially as Vytorin or Inegy. In dogs, after 18 days of treatment with simvastatin at a dose of 8 mg/kg per day, plasma cholesterol levels were reduced by 33%.3↗ Simvastatin also suppresses TNF-induced NF-κB activation (IC50 ~ 13 µM), which potentiates apoptosis in human myeloid leukemia cells and thus, may be useful in treating cancer.4↗
Synonyms Zocor™
Formal Name (βR,​δR,​1S,​2S,​6R,​8S,​8aR)-​8-​(2,​2-​dimethyl-​1-​oxobutoxy)-​1,​2,​6,​7,​8,​8a-​hexahydro-​β,​δ-​dihydroxy-​2,​6-​dimethyl-​1-​naphthaleneheptanoic acid,​ monosodium salt
CAS Number 101314-97-0
Molecular Formula C25H39O6 • Na
Formula Weight 458.6
Formulation A crystalline solid
Purity ≥98%
λmax 231, 238, 246 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES C[C@@H]​1C[C@H]​(OC(C(C)​(CC)​C)​=O)​C2C(C=C[C@H]​(C)​[C@@H]​2CC[C@@H]​(O)​C[C@@H]​(O)​CC([O-]​)​=O)​=C1.[Na]​ 
InCHI Code ​1S/C25H40O6.Na/c1-6-25(4,5)​24(30)​31-21-12-15(2)​11-17-8-7-16(3)​20(23(17)​21)​10-9-18(26)​13-19(27)​14-22(28)​29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)​;/p-1/t15-,16-,18+,19+,20-,21-,23;/m0./s1 
InCHI Key SVIXZYADIXSPPP-SBRLSJPESA-M

-20°C

10010345-25   Simvastatin (sodium salt)   品牌 Cayman

Simvastatin (sodium salt)

货号: 10010345-25      产品名称: Simvastatin (sodium salt)   品牌: Cayman 规格: 25 mg 3周

Simvastatin (sodium salt)
Cayman Chemical Item Number 10010345
Description HMG-CoA reductase is the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the “statin” class of cholesterol-lowering drugs.1↗ Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.12 nM for the hydrolyzed, open ring form of the molecule.2↗ Simvastatin is marketed under the trade name Zocor™ and is often prescribed in combination with ezetimibe (Zetia) to treat dyslipidemia. This drug combination is known commercially as Vytorin or Inegy. In dogs, after 18 days of treatment with simvastatin at a dose of 8 mg/kg per day, plasma cholesterol levels were reduced by 33%.3↗ Simvastatin also suppresses TNF-induced NF-κB activation (IC50 ~ 13 µM), which potentiates apoptosis in human myeloid leukemia cells and thus, may be useful in treating cancer.4↗
Synonyms Zocor™
Formal Name (βR,​δR,​1S,​2S,​6R,​8S,​8aR)-​8-​(2,​2-​dimethyl-​1-​oxobutoxy)-​1,​2,​6,​7,​8,​8a-​hexahydro-​β,​δ-​dihydroxy-​2,​6-​dimethyl-​1-​naphthaleneheptanoic acid,​ monosodium salt
CAS Number 101314-97-0
Molecular Formula C25H39O6 • Na
Formula Weight 458.6
Formulation A crystalline solid
Purity ≥98%
λmax 231, 238, 246 nm
Stability 2 years
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere
SMILES C[C@@H]​1C[C@H]​(OC(C(C)​(CC)​C)​=O)​C2C(C=C[C@H]​(C)​[C@@H]​2CC[C@@H]​(O)​C[C@@H]​(O)​CC([O-]​)​=O)​=C1.[Na]​ 
InCHI Code ​1S/C25H40O6.Na/c1-6-25(4,5)​24(30)​31-21-12-15(2)​11-17-8-7-16(3)​20(23(17)​21)​10-9-18(26)​13-19(27)​14-22(28)​29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)​;/p-1/t15-,16-,18+,19+,20-,21-,23;/m0./s1 
InCHI Key SVIXZYADIXSPPP-SBRLSJPESA-M

-20°C

BML-G244-0050   Simvastatin   品牌 Biomol

Simvastatin

货号: BML-G244-0050      产品名称: Simvastatin   品牌: Biomol 规格: 50 mg 3周到货 生化实验

Product Specification
Alternative Name:Zocor
Formula:C25H38O5
MW:418.6
CAS:79902-63-9
MI:14: 8539
RTECS:EK7798000
Purity:≥98% (TLC)
Appearance:White solid.
Solubility:Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml); insoluble in water.
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.

-20°C

BML-G244-0250   Simvastatin   品牌 Biomol

Simvastatin

货号: BML-G244-0250      产品名称: Simvastatin   品牌: Biomol 规格: 250 mg 3周到货 生化实验

Product Specification
Alternative Name:Zocor
Formula:C25H38O5
MW:418.6
CAS:79902-63-9
MI:14: 8539
RTECS:EK7798000
Purity:≥98% (TLC)
Appearance:White solid.
Solubility:Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml); insoluble in water.
Long Term Storage:-20°C
Use/Stability:Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.

-20°C