Cabozantinib
货号: C0006-250 mg 产品名称: Cabozantinib 品牌: LKT 规格: 250 mg 三周到货 生化试验
Cabozantinib
Description
Cabozantinib or XL-184 is a tyrosine kinase (c-MET, VEGFR2) inhibitor. It has been shown to reduce tumor growth, metastasis, angiogenesis, and induce apoptosis.
Specifications
Cas No. 849217-68-1
Product ID C0006
Product Name Cabozantinib
Chemical Name N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Synonym XL-184, BMS-907351
Formula Wt. 501.51
Solubility Soluble in DMSO (≥117mg/mL), insoluble in water (≤1 mg/mL).
References Yakes FM, Chen J, Tan J, et al. Mol Cancer Ther. 10:2298-308 (2011). Agarwal N, Sonpavde G, Sternberg CN. Eur Utol 61:950-60 (2012).
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