SIRT1 Inhibitor, EX-527
货号： 1652-10 产品名称： SIRT1 Inhibitor, EX-527 品牌： Biovision 规格： 10 mg 3周到货 生化实验
SIRT1 Inhibitor, EX-527
Product Overview
Product Name: SIRT1 Inhibitor, EX-527
Alternate Name/Synonyms: EX-527, 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Description: A potent SIRT1 inhibitor (IC₅₀ = 38 nM). EX-527 is 200-500-fold more selective for SIRT1 than for SIRT2 or SIRT3. Does not inhibit SIRT4-7, does not inhibit class I/II HDAC activity at concentrations up to 100µM. Enhances p53 acetylation in response to DNA damaging agents.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 49843-98-3
Molecular Formula: C₁₃H₁₃ClN₂O
Molecular Weight: 248.71
Purity: ≥97% by HPLC
Solubility:DMSO (20 mg/ml)
Storage Temp.: +4°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
InChi: InChI=1S/C13H13ClN2O/c14-7-4-5-11-10(6-7)8-2-1-3-9(13(15)17)12(8)16-11/h4-6,9,16H,1-3H2,(H2,15,17)
InChi Key: FUZYTVDVLBBXDL-UHFFFAOYSA-N
PubChem CID: 5113032
MDL Number: MFCD03009471
USAGE: For Research Use Only! Not For Use in Humans.
+4°C
