Thioflavin T *UltraPure grade*
货号： 23060 产品名称： Thioflavin T *UltraPure grade* 品牌： AAT 规格： 1 g 二周到货 生化试验
Thioflavin T *UltraPure grade*
Cat # 23060
Storage F/D/L (see storage codes below)
Unit Size 1 g
Ex (nm) 412
Em (nm) 482
MW 318.87
Solvent DMSO
Thioflavin T (ThT), also called Basic Yellow 1 or CI 49005, is a benzothiazole salt. The dye is used to visualize plaques composed of beta-amyloid found in the brains of Alzheimer’s disease patients. When it binds to beta sheets, such as those in amyloid oligomers, the dye undergoes a characteristic 120 nm red shift of its excitation spectrum that may be selectively excited at 450 nm, resulting in a fluorescence signal at 482 nm. ThT binds rapidly and specifically to the anti-parallel beta-sheet fibrils formed from synthetic beta-amyloid (1-40), but does not bind to monomer or oligomeric intermediates. The binding of ThT does not interfere with the aggregation of beta-amyloid peptide into amyloid fibrils.
Detailed Information: Protocol References MSDS Spectrum
Related Products: Beta-Amyloid Analysis Neurological Stains
Storage Codes:
D = Desiccated
L = Avoid light
F = Freeze (<-15 癈)
R = Refrigerated (2-4 癈)
RT = Room temperature (4-50 癈)
