Lapatinib Ditosylate (Tykerb, Tyverb, GW-572016)
货号： 1624-25 产品名称： Lapatinib Ditosylate (Tykerb, Tyverb, GW-572016) 品牌： Biovision 规格： 25 mg 3周到货 生化实验
Lapatinib Ditosylate (Tykerb, Tyverb, GW-572016)
Product Overview
Product Name: Lapatinib Ditosylate (Tykerb, Tyverb, GW-572016)
Alternate Name/Synonyms: GW-57201, Tykerb, Tyverb
Description: Lapatinib is a potent inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM), ErbB-4 kinase (Ki = 347 nM). Lapatinib can restore tamoxifen sensitivity in tamoxifen-resistant, ER-positive breast cancer models.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 388082-78-8
Molecular Formula: C₂₉H₂₆ClFN₄O₄S.2C₇H₈O₃S
Molecular Weight: 925.46
Purity: ≥99% by HPLC
Solubility:DMSO (200 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
InChi: InChI=1S/C29H26ClFN4O4S.2C7H8O3S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19;2*1-6-2-4-7(5-3-6)11(8,9)10/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35);2*2-5H,1H3,(H,8,9,10)
InChi Key: UWYXLGUQQFPJRI-UHFFFAOYSA-N
PubChem CID: 9941095
MDL Number: MFCD18904381
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
