PAC-1
货号： 1654-10 产品名称： PAC-1 品牌： Biovision 规格： 10 mg 3周到货 生化实验
PAC-1
Product Overview
Product Name: PAC-1
Alternate Name/Synonyms: 2-[[2-Hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide 4-(phenylmethyl)-1-piperazineacetic acid
Description: Procaspase-activating compound 1 (PAC-1) directly activates procaspase-3 to caspase-3, a transformation that allows induction of apoptosis even in cells that have defective apoptotic machinery. In cancer cells, PAC-1 had an IC₅₀ value of 3 nM for induction of cell death, whereas in cells from adjacent normal tissue had IC₅₀ values of 3.2-8.5 µM.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 315183-21-2
Molecular Formula: C₂₃H₂₈N₄O₂
Molecular Weight: 392.49
Purity: ≥95% by HPLC
Solubility:DMSO
Storage Temp.: +4°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC2)CC3=CC=CC=C3)C1=O
InChi: InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,24H,1,7,12-15,17-18H2,(H,25,28)/b21-16-
InChi Key: XSGXRYNZNGUGEJ-PGMHBOJBSA-N
PubChem CID: 6851947
MDL Number: MFCD03302441
USAGE: For Research Use Only! Not For Use in Humans.
+4°C
