ABT-888
货号： 1620-5 产品名称： ABT-888 品牌： Biovision 规格： 5 mg 3周到货 生化实验
ABT-888
Product Overview
Product Name: ABT-888
Alternate Name/Synonyms: 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide . dihydrochloride
Description: Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models.
Peptide Sequence: N/A
Appearance: Coloreless to white crystalline solid
Formulation: N/A
CAS Number: 912445-05-7
Molecular Formula: C₁₃H₁₆N₄O.2HCl
Molecular Weight: 317.21
Purity: ≥98% by HPLC
Solubility:DMSO and H₂O
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N
InChi: InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1
InChi Key: JNAHVYVRKWKWKQ-CYBMUJFWSA-N
PubChem CID: 11960529
MDL Number: MFCD16661206
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
