SB-431542
货号： 1674-1 产品名称： SB-431542 品牌： Biovision 规格： 1 mg 3周到货 生化实验
SB-431542
Product Overview
Product Name: SB-431542
Alternate Name/Synonyms: 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Description: A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC₅₀ = 94 nM). It inhibits ALK4 only at higher concentrations (IC₅₀ = 140 nM). Suppresses renewal in embryonic and induced pluripotent stem (iPS) cells and promotes their differentiation through its effect on Smad signaling pathway.
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 301836-41-9
Molecular Formula: C₂₂H₁₈N₄O₃
Molecular Weight: 384.39
Purity: ≥98% by HPLC
Solubility:DMSO (20 mg/ml) or EtOH (2 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
InChi: InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
InChi Key: FHYUGAJXYORMHI-UHFFFAOYSA-N
PubChem CID: 4521392
MDL Number: MFCD11045982
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
