SIRT2 Inhibitor, AGK2
货号： 1651-10 产品名称： SIRT2 Inhibitor, AGK2 品牌： Biovision 规格： 10 mg 3周到货 生化实验
SIRT2 Inhibitor, AGK2
Product Overview
Product Name: SIRT2 Inhibitor, AGK2
Alternate Name/Synonyms: AGK2, (2E)-2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)prop-2-enamide
Description: A potent inhibitor of sirtuin 2 (SIRT2) (IC₅₀ = 3.5 µM). AGK2 is >15-fold more selective for SIRT2 than SIRT1 and SIRt3. Inhibition of SIRT2 rescued α-synuclein toxicity and modified inclusion morphology in a cellular model of Parkinson’s disease.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 304896-28-4
Molecular Formula: C₂₃H₁₃Cl₂N₃O₂
Molecular Weight: 434.27
Purity: ≥95% by HPLC
Solubility:DMSO
Storage Temp.: +4°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: C1=CC2=C(C=CC=N2)C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N
InChi: InChI=1S/C23H13Cl2N3O2/c24-15-6-8-19(25)18(12-15)22-9-7-16(30-22)11-14(13-26)23(29)28-21-5-1-4-20-17(21)3-2-10-27-20/h1-12H,(H,28,29)/b14-11+
InChi Key: SVENPFFEMUOOGK-SDNWHVSQSA-N
PubChem CID: 2130404
MDL Number: MFCD01909444
USAGE: For Research Use Only! Not For Use in Humans.
+4°C
