PD-0325901
货号： 1643-25 产品名称： PD-0325901 品牌： Biovision 规格： 25 mg 3周到货 生化实验
PD-0325901
Product Overview
Product Name: PD-0325901
Alternate Name/Synonyms: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2[(2-fluoro-4-iodophenyl)amino]-benzamide
Description: A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC₅₀ = 0.33 nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of embryonic stem (ES) cells.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 391210-10-9
Molecular Formula: C₁₆H₁₄F₃IN₂O₄
Molecular Weight: 482.2
Purity: ≥95% by HPLC
Solubility:DMSO (20 mg/ml) of EtOH (20 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
InChi: InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1
InChi Key: SUDAHWBOROXANE-SECBINFHSA-N
PubChem CID: 9826528
MDL Number: MFCD08435926
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
