Enzastaurin (LY317615)
货号： 1619-1 产品名称： Enzastaurin (LY317615) 品牌： Biovision 规格： 1 mg 3周到货 生化实验
Enzastaurin (LY317615)
Product Overview
Product Name: Enzastaurin (LY317615)
Alternate Name/Synonyms: LY317615, LY-317615, D04014
Description: Enzastaurin (Enz) is a potent and selective inhibitor of PKCβ with antiproliferative activity (IC₅₀= ~6 nM). Enz suppresses VEGF-induced angiogenesis in the rat corneal micropocket assay, decreases microvessel density, and prevents VEGF secretion from human tumor cell xenografts in nude mice. Prolonged courses of Enz increase chemotherapy or radiation tumor growth delay of glioma, breast, and small cell lung cancer xenografts.
Peptide Sequence: N/A
Appearance: Red-Orange Solid
Formulation: N/A
CAS Number: 170364-57-5
Molecular Formula: C₃₂H₂₉N₅O₂
Molecular Weight: 515.61
Purity: ≥99% by HPLC
Solubility:DMSO (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Handling: Protect from air and light
SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7
InChi: InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)
InChi Key: AXRCEOKUDYDWLF-UHFFFAOYSA-N
PubChem CID: 176167
MDL Number: MFCD11040980
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
