pfuse-mg2bfc2   pFUSE-mIgG2B-Fc2   品牌 Invivogen

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pFUSE-mIgG2B-Fc2

货号： pfuse-mg2bfc2      产品名称： pFUSE-mIgG2B-Fc2   品牌： Invivogen 规格： 20 μg 二周到货 生化试验

pFUSE-mIgG2b-Fc
pFUSE-mIgG2b-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG2b heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. Murine IgG2b displays high ADCC and CDC.
pFUSE-mIgG2b-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype : IgG2B mouse
Effector Activities : ADCC+++, CDC +++
Protein A binding: +++
Protein G binding: +++
Protein L binding: ++++
Both plasmids are selectable with Zeocin™.

2139-25   Ruxolitinib, Free base   品牌 Biovision

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Ruxolitinib, Free base

货号： 2139-25      产品名称： Ruxolitinib, Free base   品牌： Biovision 规格： 25 mg 3周到货 生化实验

Ruxolitinib, Free base
A potent JAK inhibitor
Product Overview
Product Name: Ruxolitinib, Free base
Alternate Name/Synonyms: INCB018424; INC18424; NCB018424; NCB18424
Description: Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC₅₀’s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 941678-49-5
Molecular Formula: C₁₇H₁₈N₆
Molecular Weight: 306.37
Purity: ≥99% by HPLC
Solubility:DMSO (25 mg/ml) or EtOH (~ 15 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChi: InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
InChi Key: HFNKQEVNSGCOJV-OAHLLOKOSA-N
PubChem CID: 25126798
MDL Number: MFCD12031592
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

pfuse-mg2bsp   pFUSE-SEAP-mG2B-Fc   品牌 Invivogen

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pFUSE-SEAP-mG2B-Fc

货号： pfuse-mg2bsp      产品名称： pFUSE-SEAP-mG2B-Fc   品牌： Invivogen 规格： 20 μg 二周到货 生化试验

pFUSE-SEAP-mG2B-Fc
pFUSE-SEAP-mIgG2b-Fc allows the production of a SEAP-Fc fusion protein with the Fc region of the murine IgG2b. This plasmid can be used to make recombinant SEAP-Fc fusion proteins or used as a transfection control in experiments with other pFUSE-Fc constructs.
Quantification of SEAP-Fc expression can be determined using SEAP Reporter Assay Kit or QUANTI-Blue™.
Isotype: Mouse IgG2b
This plasmid is selectable with Zeocin™.

2141-100   Imatinib, Free base   品牌 Biovision

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Imatinib, Free base

货号： 2141-100      产品名称： Imatinib, Free base   品牌： Biovision 规格： 100 mg 3周到货 生化实验

Imatinib, Free base
A bcr-abl tyrosine kinase inhibitor
Product Overview
Product Name: Imatinib, Free base
Alternate Name/Synonyms: CGP-57148B, STI-571
Description: A free base form of Imatinib Mesylate (Cat. No. 1625-100, 1000).
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 152459-95-5
Molecular Formula: C₂₉H₃₁N₇O
Molecular Weight: 493.6
Purity: ≥99% by HPLC
Solubility:DMSO (25 mg/ml) or EtOH (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
InChi: InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
InChi Key: KTUFNOKKBVMGRW-UHFFFAOYSA-N
PubChem CID: 5291
MDL Number: MFCD05662257
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

2141-1000   Imatinib, Free base   品牌 Biovision

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Imatinib, Free base

货号： 2141-1000      产品名称： Imatinib, Free base   品牌： Biovision 规格： 1 g 3周到货 生化实验

Imatinib, Free base
A bcr-abl tyrosine kinase inhibitor
Product Overview
Product Name: Imatinib, Free base
Alternate Name/Synonyms: CGP-57148B, STI-571
Description: A free base form of Imatinib Mesylate (Cat. No. 1625-100, 1000).
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 152459-95-5
Molecular Formula: C₂₉H₃₁N₇O
Molecular Weight: 493.6
Purity: ≥99% by HPLC
Solubility:DMSO (25 mg/ml) or EtOH (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
InChi: InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
InChi Key: KTUFNOKKBVMGRW-UHFFFAOYSA-N
PubChem CID: 5291
MDL Number: MFCD05662257
USAGE: For Research Use Only! Not For Use in Humans.

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pfuse-mg3fc1   pFUSE-mIgG3-Fc1   品牌 Invivogen

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pFUSE-mIgG3-Fc1

货号： pfuse-mg3fc1      产品名称： pFUSE-mIgG3-Fc1   品牌： Invivogen 规格： 20 μg 二周到货 生化试验

pFUSE-mIgG3-Fc
pFUSE-mIgG3-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG3 heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-mIgG3-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype : IgG3 mouse
Effector Activities : ADCC+++, CDC +
Protein A binding: ++
Protein G binding: +++
Protein L binding: ++++
Both plasmids are selectable with Zeocin™.

2142-25   BAY 43-9006, Free base   品牌 Biovision

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BAY 43-9006, Free base

货号： 2142-25      产品名称： BAY 43-9006, Free base   品牌： Biovision 规格： 25 mg 3周到货 生化实验

BAY 43-9006, Free base
A VEGFR and PDGFR kinase inhibitor
Product Overview
Product Name: BAY 43-9006, Free base
Alternate Name/Synonyms: Sorafenib
Description: A free base form of BAY 43-9006 (Cat. No. 1594-25,100).
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 284461-73-0
Molecular Formula: C₂₁H₁₆ClF₃N₄O₃
Molecular Weight: 464.82
Purity: ≥99% by HPLC
Solubility:DMSO (200 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F
InChi: InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)
InChi Key: MLDQJTXFUGDVEO-UHFFFAOYSA-N
PubChem CID: 216239
MDL Number: MFCD06411450
USAGE: For Research Use Only! Not For Use in Humans.

-20°C