标签归档：kinase

2046-5   Sphingosine Kinase Inhibitor, SKI-I   品牌 Biovision

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Sphingosine Kinase Inhibitor, SKI-I

货号： 2046-5      产品名称： Sphingosine Kinase Inhibitor, SKI-I   品牌： Biovision 规格： 5 mg 3周到货 生化实验

Sphingosine Kinase Inhibitor, SKI-I
A non-lipid pan-sphingosine kinase (SK) inhibitor
Product Overview
Product Name: Sphingosine Kinase Inhibitor, SKI-I
Alternate Name/Synonyms: 5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide
Description: Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.
Peptide Sequence: N/A
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 306301-68-8
Molecular Formula: C₂₅H₁₈N₄O₂
Molecular Weight: 406.44
Purity: ≥90% by NMR
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: O=C(N/N=C/C1C2CCCCC2CCC1O)C3CC(NN3)C4CCC5CCCCC5C4
InChi: InChI=1S/C25H18N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-15,30H,(H,27,28)(H,29,31)/b26-15+
InChi Key: XOXCTLAKMCIWCF-CVKSISIWSA-N
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

2046-25   Sphingosine Kinase Inhibitor, SKI-I   品牌 Biovision

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Sphingosine Kinase Inhibitor, SKI-I

货号： 2046-25      产品名称： Sphingosine Kinase Inhibitor, SKI-I   品牌： Biovision 规格： 25 mg 3周到货 生化实验

Sphingosine Kinase Inhibitor, SKI-I
A non-lipid pan-sphingosine kinase (SK) inhibitor
Product Overview
Product Name: Sphingosine Kinase Inhibitor, SKI-I
Alternate Name/Synonyms: 5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide
Description: Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.
Peptide Sequence: N/A
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 306301-68-8
Molecular Formula: C₂₅H₁₈N₄O₂
Molecular Weight: 406.44
Purity: ≥90% by NMR
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: O=C(N/N=C/C1C2CCCCC2CCC1O)C3CC(NN3)C4CCC5CCCCC5C4
InChi: InChI=1S/C25H18N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-15,30H,(H,27,28)(H,29,31)/b26-15+
InChi Key: XOXCTLAKMCIWCF-CVKSISIWSA-N
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

2047-5   Sphingosine Kinase Inhibitor, SKI-II   品牌 Biovision

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Sphingosine Kinase Inhibitor, SKI-II

货号： 2047-5      产品名称： Sphingosine Kinase Inhibitor, SKI-II   品牌： Biovision 规格： 5 mg 3周到货 生化实验

Sphingosine Kinase Inhibitor, SKI-II
A non-lipid pan-sphingosine kinase (SK) inhibitor
Product Overview
Product Name: Sphingosine Kinase Inhibitor, SKI-II
Alternate Name/Synonyms: 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol
Description: Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3-kinase, or PKCα at concentrations up to 60 µM.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 312636-16-1
Molecular Formula: C₁₅H₁₁ClN₂OS
Molecular Weight: 302.78
Purity: ≥90% by NMR
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)
InChi Key: ZFGXZJKLOFCECI-UHFFFAOYSA-N
PubChem CID: 753704
MDL Number: MFCD00733553
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

2047-25   Sphingosine Kinase Inhibitor, SKI-II   品牌 Biovision

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Sphingosine Kinase Inhibitor, SKI-II

货号： 2047-25      产品名称： Sphingosine Kinase Inhibitor, SKI-II   品牌： Biovision 规格： 25 mg 3周到货 生化实验

Sphingosine Kinase Inhibitor, SKI-II
A non-lipid pan-sphingosine kinase (SK) inhibitor
Product Overview
Product Name: Sphingosine Kinase Inhibitor, SKI-II
Alternate Name/Synonyms: 4-[[4-(4-Chlorophenyl)-2-thiazolyl]amino]phenol
Description: Cell-permeable. SKI-II is selective a non-lipid sphingosine kinase (SK) inhibitor. It displays non-ATP-competitive inhibition of human recombinant GST-SK 1 with an IC50 value of 0.5 µM, with no inhibition against ERK2, PI3-kinase, or PKCα at concentrations up to 60 µM.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 312636-16-1
Molecular Formula: C₁₅H₁₁ClN₂OS
Molecular Weight: 302.78
Purity: ≥90% by NMR
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC(=CC=C1C2=CSC(=N2)NC3=CC=C(C=C3)O)Cl
InChi: InChI=1S/C15H11ClN2OS/c16-11-3-1-10(2-4-11)14-9-20-15(18-14)17-12-5-7-13(19)8-6-12/h1-9,19H,(H,17,18)
InChi Key: ZFGXZJKLOFCECI-UHFFFAOYSA-N
PubChem CID: 753704
MDL Number: MFCD00733553
USAGE: For Research Use Only! Not For Use in Humans.

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K856-5   DiscoveryPak PI 3-Kinase Inhibitor Set   品牌 Biovision

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DiscoveryPak PI 3-Kinase Inhibitor Set

货号： K856-5      产品名称： DiscoveryPak PI 3-Kinase Inhibitor Set   品牌： Biovision 规格： 5 inhibitors 3周到货 生化实验

DiscoveryPak™ PI 3-Kinase Inhibitor Set
A PI 3-kinase inhibitors set
Product Overview
Alternate Name/Synonyms: PI 3-Kinase Inhibitor Set, DiscoveryPak™
Peptide sequence: N/A
Appearance: Lyophilized solids
Formulation: N/A
CAS Number: See under the individual product
Molecular Formula: See under the individual product
Molecular Weight: See under the individual product
Purity: ≥95% by HPLC
Solubility: DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: A convenient set consisting of five phosphoinositide 3-kinase (PI 3-kinase) inhibitors. The five inhibitors are: 1 mg of IC87114 (Cat. No. 1661-1), 5 mg of LY-294002 (Cat. No. 1667-5), 1 mg of PI-103 (Cat. No. 1728-1), 1 mg of PI3-Kγ inhibitor AS-605240, and 1 mg of TGX-221 (Cat. No. 1781-1).
Handling: Protect from air and light
USAGE: For Research Use Only! Not For Use in Humans.

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K858-5   DiscoveryPak EGFR Tyrosine Kinase Inhibitor Set   品牌 Biovision

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DiscoveryPak EGFR Tyrosine Kinase Inhibitor Set

货号： K858-5      产品名称： DiscoveryPak EGFR Tyrosine Kinase Inhibitor Set   品牌： Biovision 规格： 5 inhibitors 3周到货 生化实验

DiscoveryPak™ EGFR Tyrosine Kinase Inhibitor Set
An EGFR kinase inhibitors set
Product Overview
Alternate Name/Synonyms: EGFR Tyrosine Kinase Inhibitor Set, DiscoveryPak™
Peptide sequence: N/A
Appearance: Lyophilized solids
Formulation: N/A
CAS Number: See under the individual product
Molecular Formula: See under the individual product
Molecular Weight: See under the individual product
Purity: ≥95% by HPLC
Solubility: DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: A convenient set consisting of five Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase (TK) inhibitors. The five inhibitors are: 5 mg of Canertinib (Cat. No. 1617-5), 100 mg of Erlotinib, Hydrochloride (Cat. No. 1588-100), 5 mg of Gefitinib (Cat. No. 1589-5), 25 mg of Lapatinib, Ditosylate (Cat. No. 1624-25), and 2 mg of PD 153035 Hydrochloride (Cat. No. 1656-2).
Handling: Protect from air, light and moisture
USAGE: For Research Use Only! Not For Use in Humans.

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K859-8   DiscoveryPak Receptor Tyrosine Kinase (RTK) Inhibitor Set   品牌 Biovision

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DiscoveryPak Receptor Tyrosine Kinase (RTK) Inhibitor Set

货号： K859-8      产品名称： DiscoveryPak Receptor Tyrosine Kinase (RTK) Inhibitor Set   品牌： Biovision 规格： 8 inhibitors 3周到货 生化实验

DiscoveryPak™ Receptor Tyrosine Kinase (RTK) Inhibitor Set
A Receptor Tyrosine Kinase (RTK) inhibitors panel
Product Overview
Alternate Name/Synonyms: Receptor Tyrosine Kinase (RTK) Inhibitor Set, DiscoveryPak™
Peptide sequence: N/A
Appearance: Lyophilized solids
Formulation: N/A
CAS Number: See under the individual product
Molecular Formula: See under the individual product
Molecular Weight: See under the individual product
Purity: ≥95% by HPLC
Solubility: DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: A convenient set consisting of eight Receptor Tyrosine Kinase (RTK) inhibitors. The eight inhibitors are: 5 mg of Axitinib (Cat. No. 1581-5), 5 mg of Canertinib (Cat. No. 1617-5), 5 mg of Gefitinib (Cat. No. 1589-5), 5 mg of GW2580 (Cat. No. 1740-5), 25 mg of Lapatinib Ditosylate (Cat. No. 1624-25), 1 mg of PD-173074 (Cat. No. 1675-1), 1 mg of SB-431542 (Cat. No. 1674-1), and 100 mg of Sunitinib Malate (Cat. No. 1611-100).
Handling: Protect from air, light and moisture
USAGE: For Research Use Only! Not For Use in Humans.

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K862-7   PathwayReady MAP Kinase Signaling Inhibitor Panel   品牌 Biovision

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PathwayReady MAP Kinase Signaling Inhibitor Panel

货号： K862-7      产品名称： PathwayReady MAP Kinase Signaling Inhibitor Panel   品牌： Biovision 规格： 7 inhibitors 3周到货 生化实验

PathwayReady™ MAP Kinase Signaling Inhibitor Panel
A MAP kinase pathway inhibitors set
Product Overview
Alternate Name/Synonyms: MAP Kinase Signaling Inhibitor Panel, PathwayReady™
Peptide sequence: N/A
Appearance: Lyophilized solids
Formulation: N/A
CAS Number: See under the individual product
Molecular Formula: See under the individual product
Molecular Weight: See under the individual product
Purity: ≥95% by HPLC
Solubility: DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Description: A convenient set consisting of seven inhibitors useful for the study of MAP Kinase signaling pathway. The seven inhibitors are: 1 mg of PD 184352 (Cat. No. 1585-1), 5 mg of PD 98059 (Cat. No. 1666-5), 1 mg of SB 203580 (Cat. No. 1712-1), 25 mg of Sorafenib (Cat. No. 1594-25), 5 mg of SP 600125 (Cat. No. 1669-5), 5 mg of U0126 (Cat. No. 1668-5), and 1 mg of ZM 336372 (Cat. No. 1789-1).
Handling: Protect from air and light
USAGE: For Research Use Only! Not For Use in Humans.

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