IL-1 beta, rat recombinant

货号： 4130-50      产品名称： IL-1 beta, rat recombinant   品牌： Biovision 规格： 50 μg 3周到货 生化实验

IL-1beta, rat recombinant
An important mediator of inflammatory responses
Product Overview
Alternate Names / Synonyms: Rat IL-1beta, IL-1beta, IL 1beta, IL1beta, r- IL-1beta, rr-IL-1beta, recombinant rat IL-1beta, recombinant IL-1beta, IL, interluekin
Gene Symbol: IL1B
Accession #: Q63264
Gene ID: UniGene:Rn.9869
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and then lyophilized from 10 mM Sodium Acetate, pH 6.5
Molecular Weight: 17.3 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as determined by the dose-dependent stimulation of murine D10S cells is <0.1 ng/ml, corresponding to a specific activity of >1 x 10⁷ units/mg.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week or –20°C for future use.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, B-cell maturation and proliferation, mitogenic FGF-like activity and stimulation of the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C