AS601245

货号： 2162-1      产品名称： AS601245   品牌： Biovision 规格： 1 mg 3周到货 生化实验

AS601245
An ATP-competitive JNK inhibitor
Product Overview
Product Name: AS601245
Alternate Name/Synonyms: (Z)-2-(Benzo[d]thiazol-2(3H)-ylidene)-2-(2-((-(pyridine-3-yl)ethyl)amino)pyridine-4-yl)acetonitrile
Description: Cell-permeable. AS601245 is a potent, ATP-competitive JNK inhibitor (hJNK1: IC₅₀ = 150 nM, hJNK2: IC₅₀ = 220 nM and hJNK3: IC₅₀ = 70 nM). Displays anti-inflammatory properties and has been shown to reduce TNF-α plasma levels induced by LPS in mice.
Peptide Sequence: N/A
Appearance: White to yellow solid
Formulation: N/A
CAS Number:  345987-15-7
Molecular Formula: C₂₀H₁₆N₆S
Molecular Weight: 372.45
Purity: ≥95% by HPLC
Solubility:DMSO (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and mositure
SMILES: C1=CC=C2C(=C1)NC(=C(C#N)C3=NC(=NC=C3)NCCC4=CN=CC=C4)S2
InChi: InChI=1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,25H,7,10H2,(H,23,24,26)/b19-15+
InChi Key: AVLYNJZZQYEFEA-XDJHFCHBSA-N
PubChem CID: 11422035
MDL Number: MFCD07772196
USAGE: For Research Use Only! Not For Use in Humans.

-20°C