FGF- basic 147, human recombinant

货号： 4036-50      产品名称： FGF- basic 147, human recombinant   品牌： Biovision 规格： 50 μg 3周到货 生化实验

FGF-basic 147, human recombinant
A growth factor involved in angiogenesis, wound healing and embryonic development
Product Overview
Product Name: FGF- basic 147, human recombinant
Alternate Name/Synonyms: FGF2, HBGF-2, Prostatropin
Gene Symbol: FGF2
Accession #: P09038
Gene ID: 2247
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from a 10 mM Na2PO4, pH 8.0.
Molecular Weight: 16.5 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: N/A
Endotoxin Level: <0.01 ng/μg
Biological Activity: EC50 is typically 0.67-1.45 ng/ml. The activity was determined by the dose-dependent stimulation of mouse BALB/c 3T3 cells.
Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Storage Temp.: -20°C
Shipping: Blue ice
Background Information: Fibroblast Growth Factors, FGFs, are a 22 member family of proteins known to be involved in angiogenesis, wound healing and embryonic development. As a family, they bind to heparin and signal through four receptor tyrosine kinases called, FGFR1, 2, 3 and 4. Although the mechanism remains unclear, FGF-basic 147 (variant of FGF basic 154) is a critical component in keeping embryonic stem cells undifferentiated in cell culture systems. Recombinant human FGF-b 147 (FGF-2) is a non-glycosylated protein, containing 147 amino acids, and having a molecular mass of 16.5 kDa.
Amino Acid Sequence: MAPTAPNGTL EAELERRWES LVALSLARLP VAAQPKEAAV QSGAGDYLLG IKRLRRLYCN VGIGFHLQAL PDGRIGGAHA DTRDSLLELS PVERGVVSIF GVASRFFVAM SSKGKLYGSP FFTDECTFKE ILLPNNYNAY ESYKYPGMFI ALSKNGKTKK GNRVSPTMKV THFLPRL.
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-20°C