Ruxolitinib, Free base

货号： 2139-25      产品名称： Ruxolitinib, Free base   品牌： Biovision 规格： 25 mg 3周到货 生化实验

Ruxolitinib, Free base
A potent JAK inhibitor
Product Overview
Product Name: Ruxolitinib, Free base
Alternate Name/Synonyms: INCB018424; INC18424; NCB018424; NCB18424
Description: Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC₅₀’s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 941678-49-5
Molecular Formula: C₁₇H₁₈N₆
Molecular Weight: 306.37
Purity: ≥99% by HPLC
Solubility:DMSO (25 mg/ml) or EtOH (~ 15 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChi: InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
InChi Key: HFNKQEVNSGCOJV-OAHLLOKOSA-N
PubChem CID: 25126798
MDL Number: MFCD12031592
USAGE: For Research Use Only! Not For Use in Humans.

-20°C