FGF-7/KGF, murine recombinant

货号： 4051-10      产品名称： FGF-7/KGF, murine recombinant   品牌： Biovision 规格： 10 μg 3周到货 生化实验

FGF-7/KGF, murine recombinant
A potent mitogen for keratinocytes and epithelial cells
Product Overview
Alternate Names / Synonyms: HBGF-7, FGF7, FGF-7, KGF, Keratinocyte growth factor, Fibroblast growth factor 7, Heparin-binding growth factor 7
Gene Symbol: FGF7
Accession #: P36363
Gene ID: 14178
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized from a sterile filtered solution containing 20 mM Phosphate buffer pH 8 containing 0.1M NaCl
Molecular Weight: 18.9 kDa
Purity by SDS-PAGE: ≥95%
Purity by HPLC: ≥95%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ calculated by the dose-dependant stimulation of KGF-responsive BaF3 indicator cells (measured by 3H-thymidine uptake) is < 10 ng/ml corresponding to a specific activity of 100,000 Units/mg.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile ddH2O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: KGF (Keratinocyte Growth Factor-1) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis. Mouse recombinant FGF-7 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 164 amino acids and having a molecular mass of 18.9 kDa. The FGF-7 is purified by proprietary chromatographic techniques.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.

-20°C