α-Galactosylceramide

货号： 2152-1000      产品名称： α-Galactosylceramide   品牌： Biovision 规格： 1 mg 3周到货 生化实验

α-Galactosylceramide
A specific ligand for human and mouse natural killer T (NKT) cells
Product Overview
Product Name: α-Galactosylceramide
Alternate Name/Synonyms: alpha-Galactosylceramide; αGalCer; KRN7000; (2S,3S,4R)-1-O-(α-D-galactosyl)-N-hexacosanoyl-2-amino- 1,3,4-octadecanetriol
Description: α-GalCer is a specific ligand for human and mouse natural killer T (NKT) cells; exhibits potent anti-tumor activity with murine in vivo experiments including subcutaneous implanted model and metastatic models in the liver and lung. KRN7000 has been reported to show various immunological effects in infectious diseases, autoimmune disease and graft verse host disease in mice.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 158021-47-7
Molecular Formula: C₅₀H₉₉NO₉
Molecular Weight: 858.32
Purity: ≥96% by NMR
Solubility:For In vivo assay: Use 5.6% sucrose, 0.75% L-histidine and 0.5% Tween20 with heating at 60-80 ̊C. For In vitro assay: should be dissolved in DMSO at the concentration of 1 mg/ml with heating at 60-80 ̊C . The solution of 1mg/ml in DMSO can be diluted by PBS.
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)NC(COC1C(C(C(C(O1)CO)O)O)O)C(C(CCCCCCCCCCCCCC)O)O
InChi: InChI=1S/C50H99NO9/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-25-26-27-29-31-33-35-37-39-45(54)51-42(41-59-50-49(58)48(57)47(56)44(40-52)60-50)46(55)43(53)38-36-34-32-30-28-16-14-12-10-8-6-4-2/h42-44,46-50,52-53,55-58H,3-41H2,1-2H3,(H,51,54)/t42-,43+,44+,46-,47-,48-,49+,50-/m0/s1
InChi Key: VQFKFAKEUMHBLV-BYSUZVQFSA-N
PubChem CID: 2826713
MDL Number: MFCD00939559
USAGE: For Research Use Only! Not For Use in Humans.

-20°C