MPLAs
货号： tlrl-mpls 产品名称： MPLAs 品牌： Invivogen 规格： 1 mg 二周到货 生化试验
MPLA Synthetic
Synthetic lipid A from E. coli (MPLAs) is a monophosphoryl lipid A with 6 fatty acyl groups. It is structurally very similar to natural MPLA except that natural MPLA contains a mixture of 5, 6, and 7 acyl lipid A. The number of fatty acids is a major determinant of the immunogenicity of endotoxin.
Synthetic E. coli lipid A activates TLR4 but does not activate TLR2 even at high concentrations reflecting its high purity.
CAS Number: 1246298-63-4
Formula: C96H184N3O22P
Molecular weight: 1763.47
Endotoxin level: 1 x 10e6 EU/mg
Solubility: 1 mg/ml in DMSO
vac-mpls MPLAs Vaccigrade 品牌 Invivogen
MPLAs Vaccigrade
货号： vac-mpls 产品名称： MPLAs Vaccigrade 品牌： Invivogen 规格： 1 mg 二周到货 生化试验
MPLA Synthetic VacciGrade™
Synthetic lipid A
Synthetic lipid A from E. coli, serotype R515 (MPLAs) is a pure monophosphoryl lipid A compound produced by chemical synthesis.
MPLAs activates TLR4 but does not activate TLR2 reflecting its high purity. MPLAs contains 6 fatty acyl groups, while MPLA purified from bacteria contains a mixture of 5, 6, and 7 acyl lipid A.
MPLA has been tested as an adjuvant in mice and reported to induce a strong Th1 response.
MPLAs VacciGrade™ is suitable for preclinical studies. It is prepared under strict aseptic conditions. It is guaranteed sterile and thoroughly tested for the presence of endotoxins.
MPLAs VacciGrade™ is for research use only, not for use in humans.
Specificity: TLR4 agonist – Th1 response
Working concentration: 2- 20 μg/mouse
Molecular weight: 1763.47
CAS Number: 1246298-63-4
Solubility: 1 mg/ml in DMSO