标签归档：prot

10610D   EXOSOME IMMUNOPREC PROT A   品牌 Invitrogen

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EXOSOME IMMUNOPREC PROT A

货号： 10610D      产品名称： EXOSOME IMMUNOPREC PROT A   品牌： Invitrogen 规格： 1 ML 三周到货 生化试验

Exosome Immunoprecipitation Dynabeads®, protein A (Invitrogen™)
Exosome Immunoprecipitation (Protein A) enables fast and gentle magnetic isolation of exosomal proteins, causing minimal physical stress to the target protein and allowing comparison of multiple samples on the same gel.
• Maintain intact exosome protein complexes
• Reduce background significantly—low non-specific binding
• Fast protocol time—only 30 minutes
• Maximal comparison—ultra-sensitivity allows many samples on the same gel
Dynabeads® coupled to Protein A are widely used for immunoprecipitation (IP), chromatin immunoprecipitation (ChIP), and protein isolation. The magnetic properties of Dynabeads® makes them a superior alternative to sepharose or agarose slurry for immunoprecipitation, since magnetic separation technology is faster and gentler than other methods, causing minimal physical stress to the target proteins. This permits the isolation and concentration of labile composites that might otherwise dissociate or be damaged by proteases during long incubation times. Native
Ligand Type: Protein A 
Form: Beads in Suspension 
Product Size: 1 mL 
Bead Diameter: 2.8 µm 
Target Species: All species 
Isolation Technology: Magnetic Bead 
Sample Type (Specific): Exosomes 
High Throughput Compatibility: Manual Protocols 
Final Product: Protein Complexes,
Protein (Native) 
Shipping Condition: Room Temperature 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at 2 to 8 °C.

10612D   EXOSOME IMMUNOPREC PROT G   品牌 Invitrogen

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EXOSOME IMMUNOPREC PROT G

货号： 10612D      产品名称： EXOSOME IMMUNOPREC PROT G   品牌： Invitrogen 规格： 1 ML 三周到货 生化试验

Exosome Immunoprecipitation Dynabeads®, protein G (Invitrogen™)
Exosome Immunoprecipitation (Protein G) enables fast and gentle magnetic isolation of exosomal proteins, causing minimal physical stress to the target protein and allowing comparison of multiple samples on the same gel.
• Maintain intact exosome protein complexes
• Reduce background significantly—low non-specific binding
• Fast protocol time—only 30 minutes
• Maximal comparison—ultra-sensitivity allows many samples on the same gel
Dynabeads® coupled to Protein G are widely used for immunoprecipitation (IP), chromatin immunoprecipitation (ChIP), and protein isolation. The magnetic properties of Dynabeads® makes them a superior alternative to sepharose or agarose slurry for immunoprecipitation, since magnetic separation technology is faster and gentler than other methods, causing minimal physical stress to the target proteins. This permits the isolation and concentration of labile composites that might otherwise dissociate or be damaged by proteases during long incubation times. Native
Ligand Type: Protein G 
Form: Beads in Suspension 
Product Size: 1 mL 
Bead Diameter: 2.8 µm 
Target Species: All species 
Isolation Technology: Magnetic Bead 
Sample Type (Specific): Exosomes 
High Throughput Compatibility: Manual Protocols 
Final Product: Protein Complexes,
Protein (Native) 
Shipping Condition: Room Temperature 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store at 2 to 8 °C.

ABC67   Anti-Mitochondrial fission 1 prot (Fis1)   品牌 Millipore

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Anti-Mitochondrial fission 1 prot (Fis1)

货号： ABC67      产品名称： Anti-Mitochondrial fission 1 prot (Fis1)   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Mitochondrial fission 1 protein (Fis1)
Species Reactivity Key Applications Host Format Antibody Type
H  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Mitochondrial fission 1 protein (Fis1) Antibody
Promotional Text:
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Specificity:
This antibody recognizes the cytoplasmic topological domain of Mitochondrial fission 1 protein.
Molecular Weight:
~17 kDa observed
Epitope:
Cytoplasmic topological domain
Immunogen:
KLH-conjugated-linear peptide corresponding to the cytoplasmic topological domain of human Mitochondrial fission 1 protein.
Background Information:
Mitochondrial fission 1 protein, hFIs1, is an overexpressed mammlian protein that is localized to the outer mitochondrial membrane of various cell types. It is involved in the fragmentation of the mitochondrial network and its perinuclear clustering, resulting in the release of cytochrome c from the mitochondrion, and apopotosis. It is known to mediate peroxisomal fission and also plays a critical role in histone function by demethylating Lys-4 of histone H3.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human.
Other homologies: Rat and Mouse (83% sequence homology).
Control:
Raji cell lysate
Quality Assurance:
Evaluated by Western Blot in Raji cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Mitochondrial fission 1 protein in 10 µg of Raji cell lysate.
Purification Method:
Affinity Purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q9Y3D6
Entrez Gene Number:
NP_057152
Gene Symbol:
FIS1
TTC11
CGI-135
Alternate Names:
FIS1 homolog
hFis1
Tetratricopeptide repeat protein 11
TPR repeat protein 11
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Entrez Gene Summary:
The balance between fission and fusion regulates the morphology of mitochondria. TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission.
UniProt Summary:
FUNCTION: Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
SUBUNIT STRUCTURE: Interacts with DNM1L/DLP1 through the TPR region. Interacts with MARCH5.
SUBCELLULAR LOCATION: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
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Product Name:
Anti-Mitochondrial fission 1 protein (Fis1)
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect Mitochondrial fission 1 protein (Fis1) using this Anti-Mitochondrial fission 1 protein (Fis1) Antibody validated for use in 2-8℃

ABF32   Anti-Fibroblast-specific Prot 1 (S100A4)   品牌 Millipore

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Anti-Fibroblast-specific Prot 1 (S100A4)

货号： ABF32      产品名称： Anti-Fibroblast-specific Prot 1 (S100A4)   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Fibroblast-specific Protein 1 (S100A4)
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PRODUCT FAMILY INFORMATION
Glial Cell Markers
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
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Species Reactivity Key Applications Host Format Antibody Type
H, M, R, B, Ca, Eq  WB, ICC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Fibroblast-specific Protein 1 (S100A4) Antibody
Promotional Text:
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100% Performance Guaranteed
Specificity:
This antibody recognizes S100A4 at the C-terminus.
Molecular Weight:
~12 kDa observed
Epitope:
C-terminus
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminus of human S100A4.
Background Information:
S100A4, also known as Fibroblast-specific Protein 1, is a member of the Ca2+- dependent S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 is a metastasis factor that may function in motility, invasion, and tubulin polymerization. Increased expression of S100A4 has been associated with various types of cancer.
Species Reactivity:
Human
Mouse
Rat
Bovine
Canine
Horse
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Species Reactivity Note:
Demonstrated to react with Human, Mouse, and Rat.
Predicted to react with Bovine, Canine, and Equine based on 100% sequence homology.
Application Notes:
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected S100A4 in mouse neural stem cells.
Control:
HeLa cell lysate
Quality Assurance:
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected S100A4 in 10 µg of HeLa cell lysate.
Purification Method:
Affinity Purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P26447
Entrez Gene Number:
NP_002952
Gene Symbol:
S100A4
CAPL
MTS1
Alternate Names:
Protein S100-A4
Calvasculin
Metastasin
Placental calcium-binding protein
Protein Mts1
S100 calcium-binding protein A4
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunocytochemistry
Entrez Gene Summary:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have bee 2-8℃

MABN310   Anti-G-prot CoupledReceptor56(GPR56),cln   品牌 Millipore

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Anti-G-prot CoupledReceptor56(GPR56),cln

货号： MABN310      产品名称： Anti-G-prot CoupledReceptor56(GPR56),cln   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-G-protein coupled receptor 56 (GPR56), clone H11
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REFERENCES
G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination.
Luo, Rong, et al. (2011) Proc. Natl. Acad. Sci. U.S.A., 108: 12925-30 (2011)
Species Reactivity Key Applications Host Format Antibody Type
M  WB, ICC, IHC Mouse Purified Monoclonal Antibody
Description:
Anti-G-protein coupled receptor 56 (GPR56) Antibody, clone H11
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Molecular Weight:
~62 kDa observed. Full-length GPR56 (GPR56FL) migrates at 75 kDa and the cleaved extracellular domain of GPR56 (GPR56ECD) migrates at 62 kDa. (J Biol Chem. 2008 May 23;283(21):14469-78).
Immunogen:
N-terminal fragment of mouse GPR56
Clone:
H11
Isotype:
IgG1κ
Background Information:
G-protein coupled receptor 56 (GPR56) is a ubiquitous adhesion receptor, which belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. It is abundantly expressed in the in thyroid gland, brain, heart, and various tumor cells. Previous studies have suggested that GPR56 may inhibit the progression and metastasis of melanomas by interaction with extracellular-matrix proteins, such as Tissue Transglutaminase. GPR56 also plays a role in regulating VEGF production and angiogenesis via a PKCα-mediated pathway. GPR56 also plays a critical role in the development of the frontal cortex; previous studies have reported that mutations in GPR56 result in disorganized cortical lamination, which is most pronounced in the frontal cortex. This condition is known as bilateral frontoparietal polymicrogyria or BFPP.
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Species Reactivity:
Mouse
Species Reactivity Note:
Demonstrated to react with Mouse. Predicted to react with Human based on 100% sequence homology.
Application Notes:
Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in E14.5 mouse brain tissue. (Luo, R., et al. (2011). Proc Natl Acad Sci U S A. 108(31):12925-12930.)
Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in meningeal fibroblasts (MFs). (Luo, R., et al. (2011). Proc Natl Acad Sci U S A. 108(31):12925-12930.)
View All »
Control:
Brain tissue lysate from E13-E14 mouse
Quality Assurance:
Evaluated by Western Blot in brain tissue lysate from E13-E14 mouse.
Western Blot Analysis: 0.5 μg/mL of this antibody detected G-protein coupled receptor 56 in 10 µg of brain tissue lysate from E13-E14 mouse.
Purification Method:
Protein G purified
Presentation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q8K209
Entrez Gene Number:
NP_001185823
Gene Symbol:
GPR56
TM7XN1
TM7LN4
EGF-TM7-like
BFPP
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Alternate Names:
G protein-coupled receptor 56
7-transmembrane protein with no EGF-like N-terminal domains-1
Protein TM7XN1
G-protein coupled receptor 56
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Weste 2-8℃

06-157   A HU GAP PROT A PURE 200UG   品牌 Millipore

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A HU GAP PROT A PURE 200UG

货号： 06-157      产品名称： A HU GAP PROT A PURE 200UG   品牌： Millipore 规格： EA 3周到货 生化实验

Anti-RasGAP Antibody
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REFERENCES
The extreme carboxyl terminus of v-Abl is required for lymphoid cell transformation by Abelson virus.
David Warren, Deborah S Griffin, Celine Mainville, Naomi Rosenberg, David Warren, Deborah S Griffin, Celine Mainville, Naomi Rosenberg (2003) Journal of virology.77:4617-25
Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney.
Ruff, S J, et al. (1997) J. Biol. Chem., 272: 1263-7 (1997)
Mechanical strain induces pp60src activation and translocation to cytoskeleton in fetal rat lung cells.
Liu, M, et al. (1996) J. Biol. Chem., 271: 7066-71 (1996)
A conserved region of c-Ha-Ras is required for efficient GTPase stimulation by GTPase activating protein but not neurofibromin.
Yoder-Hill, J, et al. (1995) J. Biol. Chem., 270: 27615-21 (1995)
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Species Reactivity Key Applications Host Format Antibody Type
Av, H, M, R  IP, WB Rabbit Purified Polyclonal Antibody
Description:
Anti-RasGAP Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Specificity:
GAP
Molecular Weight:
120kDa
Immunogen:
Trp E fusion corresponding to residues 171-448 of human RasGAP
Isotype:
IgG
Species Reactivity:
Avian
Human
Mouse
Rat
Quality Assurance:
Western Immunoblot Analysis: This antibody, at 0.5 and 2.0 μg/ml, recognized the 120 kDa GAP protein in a RIPA lysate of human Raji lymphocyte cells, lysates of rat L6 myoblasts and mouse Wehi leukemia cells.
Immunoprecipitation: 5 μg of this antibody immunoprecipitated the 120kDa GAP protein from a RIPA lysate of human Raji lymphocyte cells.
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Purification Method:
Protein A chromatography
Presentation:
200 μg of protein-A purified IgG. Lyophilized from 200 μl of 0.1 M Tris-HCl, 0.15 M NaCl, and 0.05% Na Azide.
Storage Conditions:
Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C Rehydrate in 200 μl of water.
UniProt Number:
P20936
Entrez Gene Number:
NM_022650
Gene Symbol:
RASA1
CMAVM
CM-AVM
RASA
PKWS
GAP
p120GAP
RASGAP
RasGAP
DKFZp434N071
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Immunoprecipitation
Western Blotting
Entrez Gene Summary:
The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
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UniProt Summary:
FUNCTION: SwissProt: P20936 # I -20°C

06-222   ANTI-PROT PHOSPHATASE-2A 200UG   品牌 Millipore

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ANTI-PROT PHOSPHATASE-2A 200UG

货号： 06-222      产品名称： ANTI-PROT PHOSPHATASE-2A 200UG   品牌： Millipore 规格： EA 3周到货 生化实验

Anti-PP2A Antibody, C subunit
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REFERENCES
Afferent arteriolar dilation to 11, 12-EET analogs involves PP2A activity and Ca2+-activated K+ Channels.
John D Imig,Christiana Dimitropoulou,D Sudarshan Reddy,Richard E White,John R Falck (2008) Microcirculation (New York, N.Y. : 1994).15
Association of cystic fibrosis transmembrane conductance regulator and protein phosphatase 2C.
T Zhu, D Dahan, A Evagelidis, S Zheng, J Luo, J W Hanrahan (1999) The Journal of biological chemistry.274:29102-7
Postnatal changes in contractile time parameters, calcium regulatory proteins, and phosphatases
Gombosova, I, et al. (1998) Am J Physiol, 274:H2123-H2132 (1998)
Alpha-synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells
Peng, Xiangmin, et al. (2005) J Cell Sci, 118:3523-3530 (2005)
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Species Reactivity Key Applications Host Format Antibody Type
H, M, R, Rb  IP, WB Rabbit Serum Polyclonal Antibody
Description:
Anti-PP2A Antibody, C subunit
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Specificity:
Recognizes PP2A-subunit alpha and PP2A-subunit beta; does not react with PP1 or other protein phosphatases.
Molecular Weight:
36 kDa
Immunogen:
peptide corresponding to the C-terminal amino acid residues 296-309 of human protein phosphatase 2A
Isotype:
IgG
Species Reactivity:
Human
Mouse
Rat
Rabbit
Control:
Positive Control Included: Non-Stim A431 Cell Lysate (12-301). Other controls: HeLa whole cel lysate, mouse NIH3T3 cells
Quality Assurance:
routinely evaluated by immunoblot on a rabbit brain cytosol or in a human A431 RIPA cell lysate
Purification Method:
Unpurified
Presentation:
Immunoaffinity Purified immunoglobulin in 150mM Tris, pH 7.4, 0.02% sodium azide, 50% glycerol and 5mg/ml BSA
Storage Conditions:
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
UniProt Number:
P67775
P62714
Entrez Gene Number:
NM_002715.2
NP_002706
Gene Symbol:
PPP2CA
PP2CA
PP2A-alpha
RP-C
PP2Ac
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Immunoprecipitation
Western Blotting
Entrez Gene Summary:
The protein encoded by this gene is the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.
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UniProt Summary:
FUNCTION: SwissProt: P67775 # PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Can dephosphorylate SV40 large T antigen and p53. Dephosphorylates SV40 large T antigen, preferentially on serine residues 120, 123, 677, an -20°C

07-095   A-PROT PHOS METHYL PC 12-305   品牌 Millipore

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A-PROT PHOS METHYL PC 12-305

货号： 07-095      产品名称： A-PROT PHOS METHYL PC 12-305   品牌： Millipore 规格： EA 3周到货 生化实验

Anti-PP2A-methylesterase/PME-1 Antibody
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REFERENCES
A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A.
Ogris, E, et al. (1999) J. Biol. Chem., 274: 14382-91 (1999)
A protein phosphatase methylesterase (PME-1) is one of several novel proteins stably associating with two inactive mutants of protein phosphatase 2A
Ogris, E., et al (1999) J Biol Chem, 274:14382-91 (1999)
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  WB Rabbit Purified Polyclonal Antibody
Description:
Anti-PP2A-methylesterase/PME-1 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Specificity:
Protein Phosphatase Methylesterase-1
Molecular Weight:
44kDa
Immunogen:
A mixture of two nickel agarose-purified, His6-tagged, bacterial expressed human Protein Phosphatase Methylesterase-1 (PME-1) fragments (residues 225-302 and 277-387). These two fragments represent the carboxyl-terminal portion of the protein.
Isotype:
IgG
Species Reactivity:
Human
Mouse
Rat
Quality Assurance:
routinely evaluated by immunoblot on RIPA lysates from mouse 3T3 fibroblasts
Purification Method:
Protein A chromatography
Presentation:
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Storage Conditions:
2 years at -20°C
UniProt Number:
Q9Y570
Entrez Gene Number:
NM_016147
Gene Symbol:
PPME1
FLJ22226
PME-1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Key Applications:
Western Blotting
Entrez Gene Summary:
Protein phosphatase methylesterase-1 catalyzes the demethylation of the protein phosphatase-2A catalytic subunit (PPP2CA; MIM 176915) (Ogris et al., 1999 [PubMed 10318862]).[supplied by OMIM]
UniProt Summary:
FUNCTION: SwissProt: Q9Y570 # Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).
SIZE: 386 amino acids; 42315 Da
SUBUNIT: Binds PPP2CB.
SIMILARITY: SwissProt: Q9Y570 ## Belongs to the AB hydrolase superfamily.
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Brand Family:
Upstate
Product Name:
Anti-PP2A-methylesterase/PME-1 Antibody
Antibody Type:
Polyclonal Antibody
Qty/Pk:
200 µg
Format:
Purified
Host:
Rabbit
Applications:
This Anti-PP2A-methylesterase/PME-1 Antibody is validated for use in IP, WB for the detection of PP2A-methylesterase/PME-1.

-20°C