XAV939

货号： 1727-1      产品名称： XAV939   品牌： Biovision 规格： 1 mg 3周到货 生化实验

XAV939
A Tankyrase (TNKS) inhibitor
Product Overview
Product Name: XAV939
Alternate Name/Synonyms: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thi opyrano[4,3-d]pyrimidin-4-one
Description: A Tankyrase (TNKS) inhibitor (IC₅₀ = 110 nM for TNKS1 and 4 nM for TNKS2). Antagonizes wnt signaling via stimulation of β-catenin degradation and stabilization of axin. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 284028-89-3
Molecular Formula: C₁₄H₁₁F₃N₂OS
Molecular Weight: 312.31
Purity: ≥98% by HPLC
Solubility:DMSO (50 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F
InChi: InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChi Key: KLGQSVMIPOVQAX-UHFFFAOYSA-N
PubChem CID: 2726824
MDL Number: MFCD16879017
USAGE: For Research Use Only! Not For Use in Humans.

-20°C