1716-5   SCD1 Inhibitor   品牌 Biovision

SCD1 Inhibitor

货号: 1716-5      产品名称: SCD1 Inhibitor   品牌: Biovision 规格: 5 mg 3周到货 生化实验

SCD1 Inhibitor
A SCD1(stearoyl-CoA desaturase 1 inhibitor
Product Overview
Product Name: SCD1 Inhibitor
Alternate Name/Synonyms: 4-(2-Chlorophenoxy)-N-(3-(3-methylcarbamoyl)phenyl)piperidine-1-carboxamide
Description: Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1, <4 nM for mSCD1). Also exhibited in vivo efficacy with dose-dependent desaturation index lowering effect. SCD1 inhibition resulted in alterations in macrophage membrane lipid composition and marked hypersensitivity to toll-like receptor 4 agonists.
Peptide Sequence: N/A
Appearance: Crystalline solid
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₂₀H₂₂ClN₃O₃
Molecular Weight: 387.86
Purity: ≥95% by HPLC
Solubility:DMSO (~ 180 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CNC(=O)C1=CC(=CC=C1)NC(=O)N2CCC(CC2)OC3=CC=CC=C3Cl
InChi: InChI=1S/C20H22ClN3O3/c1-22-19(25)14-5-4-6-15(13-14)23-20(26)24-11-9-16(10-12-24)27-18-8-3-2-7-17(18)21/h2-8,13,16H,9-12H2,1H3,(H,22,25)(H,23,26)
InChi Key: DPYTYQFYDLYWHZ-UHFFFAOYSA-N
PubChem CID: 24905400
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.

-20°C