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310203   RABBIT COMPLEMENT-HLA-ABC FREEZE DRIED 10 X 3 ML   品牌 Invitrogen

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RABBIT COMPLEMENT-HLA-ABC FREEZE DRIED 10 X 3 ML

货号： 310203      产品名称： RABBIT COMPLEMENT-HLA-ABC FREEZE DRIED 10 X 3 ML   品牌： Invitrogen 规格： *** 三周到货 生化试验

HLA-ABC Rabbit Complement FD
8-12 Week Complemement
• Produced from large pools of New Zealand and California White (albino) rabbits 8-12 weeks of age.
• Collected under controlled methods to ensure the integrity and quality of the complement.
• Application: For use in HLA lymphocytotoxic assays.
• Tested for high titer and low background toxicity.
3-4 Week Complement
• The low heterophile activity in 3-4 week complement results in low background, making this product ideal for many uses within the research laboratory, including bactericidal and opsonization assays.
Product Size: 10 x 3 mL 
Protein Subtype: Complement
Shipping Condition: Approved for shipment at Room Temperature or on Wet or Dry Ice 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in freezer (-5 to -30°C)
Shipping: Room temperature, or wet or dry ice

31021100   RABBIT COMPLEMENT-HLA-ABC   品牌 Invitrogen

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RABBIT COMPLEMENT-HLA-ABC

货号： 31021100      产品名称： RABBIT COMPLEMENT-HLA-ABC   品牌： Invitrogen 规格： *** 三周到货 生化试验

HLA-ABC Rabbit Complement
8-12 Week Complemement
• Produced from large pools of New Zealand and California White (albino) rabbits 8-12 weeks of age.
• Collected under controlled methods to ensure the integrity and quality of the complement.
• Application: For use in HLA lymphocytotoxic assays.
• Tested for high titer and low background toxicity.
3-4 Week Complement
• The low heterophile activity in 3-4 week complement results in low background, making this product ideal for many uses within the research laboratory, including bactericidal and opsonization assays.
Product Size: 100 mL 
Protein Subtype: Complement
Shipping Condition: Dry Ice 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in ultra-cold freezer (-68 to -85°C).

31024100   RABBIT COMPLEMENT-HLA-ABC/DR   品牌 Invitrogen

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RABBIT COMPLEMENT-HLA-ABC/DR

货号： 31024100      产品名称： RABBIT COMPLEMENT-HLA-ABC/DR   品牌： Invitrogen 规格： *** 三周到货 生化试验

HLA-ABC/DR Rabbit Complement
8-12 Week Complemement
• Produced from large pools of New Zealand and California White (albino) rabbits 8-12 weeks of age.
• Collected under controlled methods to ensure the integrity and quality of the complement.
• Application: For use in HLA lymphocytotoxic assays.
• Tested for high titer and low background toxicity.
3-4 Week Complement
• The low heterophile activity in 3-4 week complement results in low background, making this product ideal for many uses within the research laboratory, including bactericidal and opsonization assays.
Product Size: 100 mL 
Protein Subtype: Complement 
Shipping Condition: Dry Ice 
Regulatory Statement: For Research Use Only. Not for use in diagnostic procedures.
Store in ultra-cold freezer (-68 to -85°C).

AB15708C3   Anti-Beta III Tubulin, Cy3 Conjugate   品牌 Millipore

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Anti-Beta III Tubulin, Cy3 Conjugate

货号： AB15708C3      产品名称： Anti-Beta III Tubulin, Cy3 Conjugate   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Beta III Tubulin, Cy3 Conjugate
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  ICC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Beta III Tubulin, Cy3 Conjugate Antibody
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Molecular Weight:
50 kDa calculated
Immunogen:
Synthetic linear peptide corresponding to human Beta III Tubulin.
Background Information:
Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
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Species Reactivity:
Human
Mouse
Rat
Species Reactivity Note:
Demonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology.
Control:
Rat E18 cortex cells
Quality Assurance:
Evaluated by Immunocytochemistry in rat E18 cortex cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q13509
Entrez Gene Number:
NP_006077
Gene Symbol:
TUBB3
TUBB4
MC1R
beta-4
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Immunocytochemistry
UniProt Summary:
FUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
SIZE: 450 amino acids; 50433 Da
SUBUNIT: Dimer of alpha and beta chains.
DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium.
SIMILARITY: Belongs to the tubulin family.
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Product Name:
Anti-Beta III Tubulin, Cy3 Conjugate
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 µL
Format:
Affinity Purified
Host:
Rabbit
Applications:
This Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.

2-8℃

AB2290C3   Anti-MAP2, Cy3 Conjugate   品牌 Millipore

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Anti-MAP2, Cy3 Conjugate

货号： AB2290C3      产品名称： Anti-MAP2, Cy3 Conjugate   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-MAP2, Cy3 Conjugate
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Species Reactivity Key Applications Host Format Antibody Type
R, M  ICC Rabbit Cy3 Polyclonal Antibody
Description:
Anti-MAP2, Cy3 Conjugate Antibody
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Molecular Weight:
The unconjugated parent antibody (Cat. No. AB2290) has an observed molecular weight at ~260 kDa.
Immunogen:
Three KLH-conjugated linear peptides corresponding to the N-terminal and central regions of rat MAP-2.
Background Information:
The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin and stabilizes microtubules. (Herzog and Weber, 1978). MAP-2 is essential for the development and maitenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.
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Species Reactivity:
Rat
Mouse
Species Reactivity Note:
Demonstrated to react with Rat. Predicted to react with Mouse based on 100% sequence homology.
Control:
Rat E18 primary cortex cells
Quality Assurance:
Evaluated by Immunocytochemistry in rat E18 primary cortex cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected MAP-2 in rat E18 primary cortex cells.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P15146
Entrez Gene Number:
NP_037198
Gene Symbol:
Map2
Mtap2
Alternate Names:
Microtubule-associated protein 2
MAP-2
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Immunocytochemistry
Entrez Gene Summary:
Regulates and organizes microtubules; may serve as a scaffolding protein for neuromodulatory activities [RGD].
UniProt Summary:
FUNCTION: The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton Probable.
DEVELOPMENTAL STAGE: Isoform MAP2C is expressed during embryonic brain development and until postanatal day 10. Isoform MAP2B is expressed throughout brain development.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR By similarity. MAP2A/c is phosphorylated.
SEQUENCE SIMILARITIES: Contains 4 Tau/MAP repeats.
Vie 2-8℃

AB5320C3   Anti-NG2 Chondroitin Sulfate Proteoglyca   品牌 Millipore

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Anti-NG2 Chondroitin Sulfate Proteoglyca

货号： AB5320C3      产品名称： Anti-NG2 Chondroitin Sulfate Proteoglyca   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-NG2 Chondroitin Sulfate Proteoglycan, Cy3 Conjugate
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PRODUCT FAMILY INFORMATION
Glial Cell Markers
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
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Pericyte Markers
Pericytes: Specialized mesenchymal cells (mesodermal origin) associated with the walls of blood vessels including capillaries of the blood-brain barrier. It is neither smooth muscle or endothelial.
Pericytes: Specialized mesenchymal cells (mesodermal origin) associated with the walls of small blood vessels including capillaries of the blood-brain barrier. It is not a smooth muscle cell nor an endothelial cell.
» More…
Species Reactivity Key Applications Host Format Antibody Type
R, M, H, Mk  ICC, IHC Rabbit Cy3 Polyclonal Antibody
Description:
Anti-NG2 Chondroitin Sulfate Proteoglycan, Cy3 Conjugate Antibody
Promotional Text:
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Specificity:
This antibody identifies the intact proteoglycan and core protein by WB and ELISA. When oligodendrocyte precursor cells (i.e. O-2A progenitor cells) are stained alive, the stain appears as clusters on the cell surface. This antibody does not stain differentiated oligodendrocytes well.
Molecular Weight:
The unconjugated parent antibody (Cat. No. AB5320) has an observed molecular weight at ~270-300 kDa.
Immunogen:
Immunoaffinity purified NG2 Chondroitin Sulfate Proteoglycan from rat
Isotype:
IgG
Background Information:
NG2 is a high molecular weight, integral membrane chondroitin sulfate proteoglycan. It is found on the surfaces of an unusual class of glial cells within the developing and mature central nervous system that have the properties of oligodendrocyte precursor cells (i.e., O-2A progenitor cells). NG2 is also found on the surfaces of chondroblasts, proliferating capillary endothelial cells, some human melanoma cell lines, and on leukemic blasts in childhood acute lymphoblastic leukemia. The NG2 proteoglycan is likely to play a role in regulation of cell motility, axon outgrowth and the cellular responses to platelet-derived growth factor.
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Species Reactivity:
Rat
Mouse
Human
Monkey
Species Reactivity Note:
Tested and passed on Rat. Predicted on Mouse, Human, Monkey based on 100% sequence homology.
Control:
Rat oligodendrocyte precursor cells
Quality Assurance:
Evaluated by Immunocytochemistry in rat oligodendrocyte precursor cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected NG2 in rat oligodendrocyte precursor cells. Performed without Triton.
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Purification Method:
Protein A purified
Presentation:
Purified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage Conditions:
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
UniProt Number:
Q6UVK1
Entrez Gene Number:
NP_001888
Gene Symbol:
CSPG4
MCSP
Alternate Names:
Chondroitin sulfate proteoglycan 4
Chondroitin sulfate proteoglycan NG2
Melanoma chondroitin sulfate proteoglycan
Melanoma-associated chondroitin sulfate proteoglycan
Usage Statement:
Unless otherwise stated in our catalog or other company documenta 2-8℃

ABC10   Anti-Megf10   品牌 Millipore

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Anti-Megf10

货号： ABC10      产品名称： Anti-Megf10   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Megf10 Antibody
Species Reactivity Key Applications Host Format Antibody Type
M  WB, IF Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Megf10 Antibody
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Specificity:
This antibody recognizes Megf10 at the cytoplasmic domain.
Molecular Weight:
~130 kDa observed
Epitope:
Cytoplasmic domain
Immunogen:
Histidine-tagged recombinant protein corresponding to the cytoplasmic domain of mouse Megf10.
Background Information:
Multiple epidermal growth factor-like domains protein 10 (Megf10) is a type 1 transmembrane protein with multiple EGF-like extracellular domains. Megf10 is highly expressed in the brain, and plays an important role in phacocytosis of apoptotic cells. This role may be performed through the interaction of Megf10 with the ATP-binding cassette transporter (ABCA1) protein. Previous studies have suggested that Megf10 may be involved in the uptake of amyloid β peptides in the brain. Megf10 may therefore play a role Alzheimer’s disease.
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Species Reactivity:
Mouse
Species Reactivity Note:
Demonstrated to react with Mouse. Other homologies: Rat (98% sequence homology) and Human (92% sequence homology).
Application Notes:
Immunofluorescence Analysis: A representative lot was used by an independent laboratory in P7 caudal brain tissue and retina cells. Image courtesy from the laboratory of Dr. Joshua Sanes, Harvard University.
Control:
Mouse retina tissue lysate
Quality Assurance:
Evaluated by Western Blot in mouse retina tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Megf10 on 10 µg of mouse retina tissue lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q6DIB5
Entrez Gene Number:
NP_001001979
Gene Symbol:
Megf10
Alternate Names:
Multiple epidermal growth factor-like domains protein 10
Multiple EGF-like domains protein 10
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunofluorescence
Product Name:
Anti-Megf10 Antibody
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect the Megf10 protein using this Anti-Megf10 validated for use in WB & IF.

2-8℃

ABC100   Anti-Hyaluronan synthase 3   品牌 Millipore

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Anti-Hyaluronan synthase 3

货号： ABC100      产品名称： Anti-Hyaluronan synthase 3   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Hyaluronan synthase 3
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REFERENCES
Cytotoxic diterpenoids from Isodon enanderianus.
Xiang, Wei, et al. (2003) Planta Med., 69: 1031-5 (2003)
Species Reactivity Key Applications Host Format Antibody Type
H  WB, IHC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Hyaluronan synthase 3 Antibody
Promotional Text:
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Specificity:
This antibody recognizes both isoforms at the cytoplasmic domain of Hyaluronan synthase 3.
Molecular Weight:
~28/60 kDa observed. An uncharacterized band appears at ~70 kDa in some lysates. The calculated molecular weight of this protein is 63 kDa for isoform 1 and 31 kDa for isoform 2, but can be observed at ~60 and ~28 kDa.
Epitope:
Cytoplasmic domain
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Hyaluronan synthase 3.
Background Information:
Hyaluronan synthase 3 (HAS3) is one of three enzymes, located at the plasma membrane, that synthesizes the glycosaminoglycan hyaluronan. Hyaluronan is involved in cell proliferation, differentiation, angiogenesis, and tumor development, among other cellular processes. Hyaluronan synthase 3 creates the low—molecular-weight hyaluronan, whereas hyaluronan synthase 1 and 2 create high molecular weight isoforms.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human.
Application Notes:
Immunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected Hyaluronan synthase 3 in human liver and human kidney tissues.
Control:
SW620 cell lysate
Quality Assurance:
Evaluated by Western Blot in SW620 cell lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected Hyaluronan synthase 3 on 10 µg of SW620 cell lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
O00219
Entrez Gene Number:
NP_005320
Gene Symbol:
HAS3
Alternate Names:
Hyaluronan synthase 3
Hyaluronate synthase 3
Hyaluronic acid synthase 3
HA synthase 3
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunohistochemistry
Product Name:
Anti-Hyaluronan synthase 3
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect Hyaluronan synthase 3 using this Anti-Hyaluronan synthase 3 Antibody validated for use in Western Blotting & IHC.

2-8℃

ABC102   Anti-CCN1/CYR61   品牌 Millipore

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Anti-CCN1/CYR61

货号： ABC102      产品名称： Anti-CCN1/CYR61   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-CCN1/CYR61
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  WB, IH(P) Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-CCN1/CYR61 Antibody
Promotional Text:
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Specificity:
This antibody recognizes the CTCK domain of: CCN1/CYR61
Molecular Weight:
~53 kDa observed. The calculated molecular weight of this protein is 42 kDa, but can be observed at higher molecular weights due to glycosylation. A degradation fragment may be observed at ~15 kDa in some lysates. (Rother et al., 2010)
Epitope:
CTCK domain
Immunogen:
KLH-conjugated linear peptide corresponding to the CTCK domain of human CCN1/CYR61.
Background Information:
CCN1 (cysteine-rich 61 or CYR61), a ubiquitous angiogenic factor, is a member of the CNN family, which is also comprised of CTGF, WISP-1, WISP-2, and WISP-3. It is a multidomain protein, containing one each of CTCK, IGFBP, TSP type-1, and VWFC domains. CCN1 is associated with the extracellular matrix and functions as a ligand for integrin receptors. It is expressed in response to growth factor stimulation, and mediates various cellular processes, including cell adhesion, migration, proliferation, angiogenesis, extracellular-matrix remodeling, and placental development. Previous studies have indicated that it may also play a role in wound healing by influencing the expression of genes required for this process, such as TIMP1, PAI-1, VEGA-A, VEGA-C, MMP1, MMP3, and uPA. CCN1 has also been implicated in breast cancer.
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Species Reactivity:
Human
Mouse
Rat
Species Reactivity Note:
Demonstrated to react with Human, Mouse, and Rat. Predicted to react with Chimpanzee based on 100% sequence homology.
Application Notes:
Immunohistochemistry Analysis: 1:200 dilution from a representative lot detected CCN1/CYR61 in human kidney tissue.
Control:
NIH/3T3 cell lysate
Quality Assurance:
Evaluated by Western Blot in NIH/3T3 cell lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected CCN1/CYR61 in 10 µg of NIH/3T3 cell lysate.
Purification Method:
Antigen Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
O00622
Entrez Gene Number:
NP_001545
Gene Symbol:
CYR61
CCN1
GIG1
IGFBP10
Alternate Names:
Protein CYR61
CCN family member 1
Cysteine-rich angiogenic inducer 61
Insulin-like growth factor-binding protein 10
IBP-10
IGF-binding protein 10
IGFBP-10
Protein GIG1
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunohistochemistry (Paraffin)
Product Name:
Anti-CCN1/CYR61
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect CCN1/CYR61 using this Anti-CCN1/CYR61 Antibody validated for us 2-8℃

ABC103   Anti-GIT2, short form   品牌 Millipore

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Anti-GIT2, short form

货号： ABC103      产品名称： Anti-GIT2, short form   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-GIT2, short form
Species Reactivity Key Applications Host Format Antibody Type
H  WB Rabbit Purified Polyclonal Antibody
Description:
Anti-GIT2, short form Antibody
Promotional Text:
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Specificity:
This antibody is specific for the short form of GIT2 (isoform 2).
Molecular Weight:
~55 kDa observed. This protein is observed at ~85 kDa when expressed in brain (Chadwick, W., et al. (2012). PLoS One. 7(5):e36975.).
Immunogen:
KLH-conjugated linear peptide corresponding to human GIT2.
Background Information:
As a member of the ADP ribosylation factor family, GIT2 acts as a GTPase-activator and serves as a G protein-coupled receptor/cytoskeletal protein. Additionally, it regulates thymocyte positive selection and motility, mediates cell adhesion and cell differentiation during embryonic development in certain species, and modulates the normal aging process. It also serves as a potential target for miR-210, a protein that induces hypoxia and plays various roles in the development of certain cancers.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human. Predicted to react with Canine and Horse based on 100% sequence homology.
Control:
Jurkat cell lysate
Quality Assurance:
Evaluated by Western Blot in Jurkat cell lysate.
Western Blot Analysis: 0.2 µg/mL of this antibody detected the short form of GIT2 in 10 µg of Jurkat cell lysate.
Purification Method:
Protein A purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q14161
Entrez Gene Number:
NP_631940
Gene Symbol:
GIT2
Alternate Names:
ARF GTPase-activating protein GIT2
ARF GAP GIT2
Cool-interacting tyrosine-phosphorylated protein 2
CAT-2
CAT2
G protein-coupled receptor kinase-interactor 2
GRK-interacting protein 2
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Product Name:
Anti-GIT2, short form
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Purified
Host:
Rabbit
Applications:
This Anti-GIT2, short form Antibody is validated for use in Western Blotting for the detection of GIT2, short form.

2-8℃

ABC105   Anti-Phospho-Src (Tyr419)   品牌 Millipore

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Anti-Phospho-Src (Tyr419)

货号： ABC105      产品名称： Anti-Phospho-Src (Tyr419)   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Phospho-Src (Tyr419)
Species Reactivity Key Applications Host Format Antibody Type
H  WB, PIA Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Phospho-Src (Tyr419) Antibody
Promotional Text:
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Specificity:
This antibody recognizes Src phosphorylated at Tyr419.
Molecular Weight:
~60 kDa observed
Epitope:
Phosphorylated Tyr419
Immunogen:
KLH-conjugated linear peptide corresponding to human Src phosphorylated at Tyr419.
Background Information:
Src is a ubiquitous non-receptor tyrosine kinase with relatively high levels of expression in neurons, osteoclasts, and platelets. It couples many different classes of cell surface receptors, including immune receptors, integrins, receptor tyrosine kinases, and cytokine receptors, to their respective intracellular signaling networks. Src recognizes activated cell surface receptors as dimers or clusters, and phosphorylates their tyrosine residues, providing binding motifs for signaling molecules. By this mechanism, Src facilitates a number of signaling pathways involved in cell adhesion, cell cycle, apoptosis, gene transcription, and cell migration. Src may also play a role in tumor development. Src is regulated by phosphorylation at multiple tyrosine residues.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human. Predicted to react with Mouse and Rat based on 100% sequence homology.
Control:
COS1 transfected with wildtype Src
Quality Assurance:
Evaluated by Western Blot/Peptide Inhibition Assay in COS1 transfected with wildtype Src.
Western Blot Analysis: 0.02 µg/mL of this antibody detected Src on 10 µg of COS1 transfected with wildtype Src.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P12931
Entrez Gene Number:
NP_005408
Gene Symbol:
SRC
SRC1
Alternate Names:
Proto-oncogene tyrosine-protein kinase Src
Proto-oncogene c-Src
pp60c-src
p60-Src
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Peptide Inhibition Assay
Product Name:
Anti-Phospho-Src (Tyr419)
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
50 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect Phospho-Src (Tyr419) using this Anti-Phospho-Src (Tyr419) Antibody validated for use in Western Blotting, Peptide Inhibition Assay.

2-8℃

ABC106   Anti-RRM2   品牌 Millipore

发表于由

Anti-RRM2

货号： ABC106      产品名称： Anti-RRM2   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-RRM2
Species Reactivity Key Applications Host Format Antibody Type
H  WB, ICC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-RRM2 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Molecular Weight:
~46 kDa observed
Immunogen:
KLH-conjugated linear peptide corresponding to the human RRM2.
Background Information:
Ribonucleoside-diphosphate reductase subunit M2 (RRM2) is a cytoplasmic protein, which catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates, and play an important role in DNA damage and repair. RRM2 has been implicated in various types of cancer.
Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human.
Application Notes:
Immunocytochemistry Analysis: A 1:500 dilution of this antibody detected RRM2 in human ESC E9 cells.
Control:
Human ESC lysate
Quality Assurance:
Evaluated by Western Blot in human ESC lysate.
Western Blot Analysis: 1 mg/mL of this antibody detected RRM2 in 10 mg of human ESC lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P31350
Entrez Gene Number:
NP_001025
Gene Symbol:
RRM2
RR2
Alternate Names:
Ribonucleoside-diphosphate reductase subunit M2
Ribonucleotide reductase small chain
Ribonucleotide reductase small subunit
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunocytochemistry
Product Name:
Anti-RRM2
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Anti-RRM2 Antibody is an antibody against RRM2 for use in Western Blotting, ICC.

2-8℃

ABC107   Anti-KIF3A   品牌 Millipore

发表于由

Anti-KIF3A

货号： ABC107      产品名称： Anti-KIF3A   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-KIF3A
Species Reactivity Key Applications Host Format Antibody Type
H  ICC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-KIF3A Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Molecular Weight:
~80 kDa observed
Immunogen:
KLH-conjugated linear peptide corresponding to human KIF3A.
Background Information:
Kinesin-like protein KIF3 (KIF3A) is a member of the heteromeric family of kinesins and plays an important role in primary cilia formation. KIF3A functions as a microtubule-based anterograde translocator for membranous organelles and forms a heterotrimeric KIF3 complex with KIF3B or KIF3C and an associated protein, KAP3. Mutations in in KIF3A have been associated with cranial base growth retardation and dysmorphogenesis.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human. Predicted to react with Baboon, Bovine, and Chimpanzee based on 100% sequence homology. Other homologies: Mouse, Rat, Chicken, Zebrafish, and Frog (92% sequence homology).
Application Notes:
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected KIF3A in A431, HeLa, and NIH/3T3 cells.
Control:
SH-SY5Y cell lysate
Quality Assurance:
Evaluated by Western Blot in SH-SY5Y cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected KIF3A in 10 µg of SH-SY5Y cell lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q9Y496
Entrez Gene Number:
NP_008985
Gene Symbol:
KIF3A
KIF3
Alternate Names:
Kinesin-like protein KIF3A
Microtubule plus end-directed kinesin motor 3A
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Immunocytochemistry
Product Name:
Anti-KIF3A
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
This Anti-KIF3A Antibody is validated for use in ICC for the detection of KIF3A.

2-8℃