Sulfobetaine 3-16
货号： 1777-5G 产品名称： Sulfobetaine 3-16 品牌： Biovision 规格： 5 g 3周到货 生化实验
Sulfobetaine 3-16
A zwitterionic detergent
Product Overview
Product Name: Sulfobetaine 3-16
Alternate Name/Synonyms: n-Hexadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; SB3-16
Description: A zwitterionic detergent useful for solubilization of membrane proteins. Retains its zwitterionic character over a broad pH range.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 2281-11-0
Molecular Formula: C₂₁H₄₅NO₃S
Molecular Weight: 391.65
Purity: ≥98% by TLC
Solubility: H₂O
Storage Temp.: RT
Shipping Conditions: RT
Handling: Protect from air and moisture
SMILES: CCCCCCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
InChi: InChI=1S/C21H45NO3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22(2,3)20-18-21-26(23,24)25/h4-21H2,1-3H3
InChi Key: TUBRCQBRKJXJEA-UHFFFAOYSA-N
PubChem CID: 92176
MDL Number: MFCD00036911
USAGE: For Research Use Only! Not For Use in Humans.
-20°C
pbla2-hflk1 pBLAST2-hFLK1 品牌 Invivogen
pBLAST2-hFLK1
货号： pbla2-hflk1 产品名称： pBLAST2-hFLK1 品牌： Invivogen 规格： 20 μg 三周到货 生化试验
FLK1(mb)
Coding sequence in expression plasmid
Alias: KDR,VEGFR2,CD309
Kinase insert domain receptor [a type III receptor tyrosine kinase], membrane-bound form.
VEGF receptor 2.
This gene is available in pUNO1 expression plasmid selectable with Blasticidin.
Product change notification
This gene which was previously available in a pBLAST plasmid is now provided in pUNO1.
Human FLK1 membrane-bound form (pUNO1-hFLK1(mb))
Genbank: AF063658
ORF Size: 4071 bp
Subclone: NcoI – NheI
RLT-102-P97-C100 TRAIL/Apo2L 品牌 AXXORA
TRAIL/Apo2L
货号： RLT-102-P97-C100 产品名称： TRAIL/Apo2L 品牌： AXXORA 规格： 100 ug
pfc1-hg1e9 pFUSE-hIgG1e9-Fc1 品牌 Invivogen
pFUSE-hIgG1e9-Fc1
货号： pfc1-hg1e9 产品名称： pFUSE-hIgG1e9-Fc1 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-hIgG1e9-Fc
pFUSE-hIgG1e9-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain mutated S239D/I332E/G236A and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-hIgG1e9-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype: IgG1 human
Mutations: S239D/I332E/G236A
Characteristics:
– Increased FcγRIIa/FcγRIIb ratio
– Increased macrophage phagocytosis
Both plasmids are selectable with Zeocin™.
pfc1-hg2e1 pFUSE-hIgG2e1-Fc1 品牌 Invivogen
pFUSE-hIgG2e1-Fc1
货号： pfc1-hg2e1 产品名称： pFUSE-hIgG2e1-Fc1 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-hIgG2e1-Fc
pFUSE-hIgG2e1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG2 heavy chain mutated K322A and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-hIgG2e1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype : IgG2 human
Mutations: K322A
Characteristics:
– Reduced binding to C1q
– Reduced CDC
Both plasmids are selectable with Zeocin™.
pfc1-mgin2 pINFUSE-mIgG2B-Fc1 品牌 Invivogen
pINFUSE-mIgG2B-Fc1
货号： pfc1-mgin2 产品名称： pINFUSE-mIgG2B-Fc1 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pINFUSE-mIgG2b-Fc
pINFUSE-mIgG2b-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the murine IgG2b heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. A short intron is present between each region (one intron between the hinge and CH2 and one intron between CH2 and CH3). The presence of introns is known to enhance the level of gene expression as splicing is known to promote rapid and efficient mRNA export.
pINFUSE-mIgG2b-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted
Murine IgG2b dispays high ADCC and CDC.
Both plasmids are selectable with Zeocin™.
pfc2-hg1e1 pFUSE-hIgG1e1-Fc2 品牌 Invivogen
pFUSE-hIgG1e1-Fc2
货号： pfc2-hg1e1 产品名称： pFUSE-hIgG1e1-Fc2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-hIgG1e1-Fc
pFUSE-hIgG1e1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain mutated T250Q/M428L and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-hIgG1e1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype: IgG1 human
Mutations: T250Q/M428L
Characteristics:
– Increased binding to neonatal FcR (FcRn)
– Increased half-life
Both plasmids are selectable with Zeocin™.
pfc2-hg1e2 pFUSE-hIgG1e2-Fc2 品牌 Invivogen
pFUSE-hIgG1e2-Fc2
货号： pfc2-hg1e2 产品名称： pFUSE-hIgG1e2-Fc2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-hIgG1e2-Fc
pFUSE-hIgG1e2-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the mutated human IgG1 heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. The engineered hIgG1e2 Fc contains the following mutations: M252Y/S254T/T256E and H433K/N434F.
pFUSE-hIgG1e2-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype: IgG1 human
Mutations: M252Y/S254T/T256E + H433K/N434F
Characteristics:
– Increased binding to neonatal FcR (FcRn)
– Increased half-life
Both plasmids are selectable with Zeocin™.
pfc2-hg1e9 pFUSE-hIgG1e9-Fc2 品牌 Invivogen
pFUSE-hIgG1e9-Fc2
货号： pfc2-hg1e9 产品名称： pFUSE-hIgG1e9-Fc2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-hIgG1e9-Fc
pFUSE-hIgG1e9-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain mutated S239D/I332E/G236A and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-hIgG1e9-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype: IgG1 human
Mutations: S239D/I332E/G236A
Characteristics:
– Increased FcγRIIa/FcγRIIb ratio
– Increased macrophage phagocytosis
Both plasmids are selectable with Zeocin™.
pfc2-hgin1 pINFUSE-hIgG1-Fc2 品牌 Invivogen
pINFUSE-hIgG1-Fc2
货号： pfc2-hgin1 产品名称： pINFUSE-hIgG1-Fc2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pINFUSE-hIgG1-Fc
pINFUSE-hIgG1-Fc1 is a cloning plasmid for the generation of a Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the human IgG1 heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently. A short intron is present between each region (one intron between the hinge and CH2 and one intron between CH2 and CH3). The presence of introns is known to enhance the level of gene expression as splicing is known to promote rapid and efficient mRNA export.
pINFUSE-hIgG1-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted
Human IgG1 displays high ADCC and CDC, and is the most suitable for therapeutic use against pathogens and cancer cells.
Both plasmids are selectable with Zeocin™.
pfuse-hchg1e2 pFUSE-CHIg-hG1e2 品牌 Invivogen
pFUSE-CHIg-hG1e2
货号： pfuse-hchg1e2 产品名称： pFUSE-CHIg-hG1e2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-hG1e2
pFUSE-CHIg-hG1e2 is a cloning plasmid that expresses the human IgG1 heavy chain constant region with M252Y / S254T / T256E + H433K / N434F mutations. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-hG1e2 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-hG1e2 features the constant region of the human IgG1 heavy chain with M252Y / S254T / T256E + H433K / N434F mutations
• pFUSEss-CHIg-hG1e1 features the constant region of the human IgG1 heavy chain with M252Y / S254T / T256E + H433K / N434F mutations and the IL2 signal sequence
Characteristics M252Y / S254T / T256E + H433K / N434F mutations:
– Increased binding to FcRn
– Increased half-life
Both plasmids are selectable with Zeocin™.
pfuse-hchg1e7 pFUSE-CHIg-hG1e7 品牌 Invivogen
pFUSE-CHIg-hG1e7
货号： pfuse-hchg1e7 产品名称： pFUSE-CHIg-hG1e7 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-hG1e7
pFUSE-CHIg-hG1e7 is a cloning plasmid that expresses the human IgG1 heavy chain constant region mutated K326W / E333S. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-hG1e7 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-hG1e7 features the constant region of the human IgG1 heavy chain mutated K326W / E333S
• pFUSEss-CHIg-hG1e7 features the constant region of the human IgG1 heavy chain mutated K326W / E333S and the IL2 signal sequence
Characteristics of K326W / E333S mutations:
– Increased binding to C1q
– Increased CDC
Both plasmids are selectable with Zeocin™.
pfuse-mchg2b pFUSE-CHIg-mG2b 品牌 Invivogen
pFUSE-CHIg-mG2b
货号： pfuse-mchg2b 产品名称： pFUSE-CHIg-mG2b 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-mG2b
pFUSE-CHIg-mG2b is a cloning plasmid that expresses the constant region of the mouse IgG2b heavy chain. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-mG2b additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-mG2b features the constant region of the mouse IgG2b heavy chain
• pFUSEss-CHIg-mG2b features the constant region of the mouse IgG2b heavy chain and the IL2 signal sequence
Both plasmids are selectable with Zeocin™.
pfuse-rtg2bfc1 pFUSE-rtIgG2B-Fc1 品牌 Invivogen
pFUSE-rtIgG2B-Fc1
货号： pfuse-rtg2bfc1 产品名称： pFUSE-rtIgG2B-Fc1 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-rtIgG2b-Fc (rat)
pFUSE-rtIgG2b-Fc1 is a cloning plasmid for the generation ofa Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the rat IgG2b heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-rtIgG2b-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype : IgG2b rat
Effector Activities : ADCC++, CDC ++
Protein A binding: –
Protein G binding: ++
Protein L binding: ++++
Both plasmids are selectable with Zeocin™.
pfuse-rtg2bfc2 pFUSE-rtIgG2B-Fc2 品牌 Invivogen
pFUSE-rtIgG2B-Fc2
货号： pfuse-rtg2bfc2 产品名称： pFUSE-rtIgG2B-Fc2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-rtIgG2b-Fc (rat)
pFUSE-rtIgG2b-Fc1 is a cloning plasmid for the generation ofa Fc-fusion protein expressing the Fc region (CH2 and CH3 domains) of the rat IgG2b heavy chain and the hinge region. The hinge serves as a flexible spacer between the two parts of the Fc-fusion protein, allowing each part of the molecule to function independently.
pFUSE-rtIgG2b-Fc2 additionally features the IL2 signal sequence for the generation of Fc-Fusion proteins derived from proteins that are not naturally secreted.
Isotype : IgG2b rat
Effector Activities : ADCC++, CDC ++
Protein A binding: –
Protein G binding: ++
Protein L binding: ++++
Both plasmids are selectable with Zeocin™.
pfusess-hchg1 pFUSEss-CHIg-hG1 品牌 Invivogen
pFUSEss-CHIg-hG1
货号： pfusess-hchg1 产品名称： pFUSEss-CHIg-hG1 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-hG1
pFUSE-CHIg-hG1 is a cloning plasmid that expresses the constant region of the human IgG1 heavy chain. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-hG1 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-hG1 features the constant region of the human IgG1 heavy chain
• pFUSEss-CHIg-hG1 features the constant region of the human IgG1 heavy chain and the IL2 signal sequence
Both plasmids are selectable with Zeocin™.
pfusess-hchg1e2 pFUSEss-CHIg-hG1e2 品牌 Invivogen
pFUSEss-CHIg-hG1e2
货号： pfusess-hchg1e2 产品名称： pFUSEss-CHIg-hG1e2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-hG1e2
pFUSE-CHIg-hG1e2 is a cloning plasmid that expresses the human IgG1 heavy chain constant region with M252Y / S254T / T256E + H433K / N434F mutations. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-hG1e2 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-hG1e2 features the constant region of the human IgG1 heavy chain with M252Y / S254T / T256E + H433K / N434F mutations
• pFUSEss-CHIg-hG1e1 features the constant region of the human IgG1 heavy chain with M252Y / S254T / T256E + H433K / N434F mutations and the IL2 signal sequence
Characteristics M252Y / S254T / T256E + H433K / N434F mutations:
– Increased binding to FcRn
– Increased half-life
Both plasmids are selectable with Zeocin™.
pfusess-hchg1e7 pFUSEss-CHIg-hG1e7 品牌 Invivogen
pFUSEss-CHIg-hG1e7
货号： pfusess-hchg1e7 产品名称： pFUSEss-CHIg-hG1e7 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-hG1e7
pFUSE-CHIg-hG1e7 is a cloning plasmid that expresses the human IgG1 heavy chain constant region mutated K326W / E333S. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-hG1e7 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-hG1e7 features the constant region of the human IgG1 heavy chain mutated K326W / E333S
• pFUSEss-CHIg-hG1e7 features the constant region of the human IgG1 heavy chain mutated K326W / E333S and the IL2 signal sequence
Characteristics of K326W / E333S mutations:
– Increased binding to C1q
– Increased CDC
Both plasmids are selectable with Zeocin™.
pfusess-hchg2 pFUSEss-CHIg-hG2 品牌 Invivogen
pFUSEss-CHIg-hG2
货号： pfusess-hchg2 产品名称： pFUSEss-CHIg-hG2 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-hG2
pFUSE-CHIg-hG2 is a cloning plasmid that expresses the constant region of the human IgG2 heavy chain. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-hG2 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-hG2 features the constant region of the human IgG2 heavy chain
• pFUSEss-CHIg-hG2 features the constant region of the human IgG2 heavy chain and the IL2 signal sequence
Both plasmids are selectable with Zeocin™.
pfusess-mchg1 pFUSEss-CHIg-mG1 品牌 Invivogen
pFUSEss-CHIg-mG1
货号： pfusess-mchg1 产品名称： pFUSEss-CHIg-mG1 品牌： Invivogen 规格： 20 μg 二周到货 生化试验
pFUSE-CHIg-mG1
pFUSE-CHIg-mG1 is a cloning plasmid that expresses the constant region of the mouse IgG1 heavy chain. It contains a multiple cloning site upstream of the constant region to enable cloning of the heavy chain variable region. This plasmid is designed for antibody generation when co-transfected into mammalian cells with the light chain variable region cloned into pFUSE-CLIg.
pFUSEss-CHIg-mG1 additionally features the IL2 signal sequence to allow the secretion of recombinant antibodies generated using fragment antigen-binding (Fab) or single-chain variable fragment (scFv) fragments selected from phage display libraries that lack a signal sequence.
• pFUSE-CHIg-mG1 features the constant region of the mouse IgG1 heavy chain
• pFUSEss-CHIg-mG1 features the constant region of the mouse IgG1 heavy chain and the IL2 signal sequence
Both plasmids are selectable with Zeocin™.