pp60c-Src C-terminal Phosphoregulatory Peptide
货号: BML-P301-0001 产品名称: pp60c-Src C-terminal Phosphoregulatory Peptide 品牌: Biomol 规格: 1 mg 3周到货 生化实验
This phosphopeptideis the C-terminal negative regulatory domain of c-Src (521-533) which includes the negative regulatory site (Tyr527). This peptide, when tyrosine-phosphorylated, binds to the internal SH2 domain.
Product Specification
Alternative Name:[pTyr527] c-Src (521-533)
Sequence:Ac-Thr-Ser-Thr-Glu-Pro-Gln-pTyr-Gln-Pro-Gly-Glu-Asn-Leu
MW:1585.7
Purity:>98%
Appearance:Lyophilized solid.
Solubility:Soluble in Water.
Long Term Storage:-20°C
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
BML-P304-0001 pp60c-Src C-terminal Peptide 品牌 Biomol
pp60c-Src C-terminal Peptide
货号: BML-P304-0001 产品名称: pp60c-Src C-terminal Peptide 品牌: Biomol 规格: 1 mg 3周到货 生化实验
This sequence, TSTEPQYQPGENL, is identical to pp60c-srv, C-terminal Phosphoregulatory Peptide, which includes the negative regulatory site (Tyr527) but is not phosphorylated. Useful as a control peptide or as a tyrosine kinase substrate. This peptide, when tyrosine-phosphorylated, binds to the internal SH2 domain.
Product Specification
Sequence:Thr-Ser-Thr-Glu-Pro-Gln-Tyr-Gln-Pro-Gly-Glu-Asn-Leu
MW:1463.7
Long Term Storage:-20°C
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
B50280 ANTI-PP4C (C-term) POLYCLONAL 品牌 Agilent
ANTI-PP4C (C-term) POLYCLONAL
货号: B50280 产品名称: ANTI-PP4C (C-term) POLYCLONAL 品牌: Agilent 规格:
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
B50305 Anti-PP2C a/b pAb 品牌 Agilent
Anti-PP2C a/b pAb
货号: B50305 产品名称: Anti-PP2C a/b pAb 品牌: Agilent 规格:
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
B50306 Sheep Anti-PP2C a/b pAb 品牌 Agilent
Sheep Anti-PP2C a/b pAb
货号: B50306 产品名称: Sheep Anti-PP2C a/b pAb 品牌: Agilent 规格:
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
B50318 Anti-PP4C (X/C) pAb 品牌 Agilent
Anti-PP4C (X/C) pAb
货号: B50318 产品名称: Anti-PP4C (X/C) pAb 品牌: Agilent 规格:
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
B50320 Anti-PP6C (V/C) pAb 品牌 Agilent
Anti-PP6C (V/C) pAb
货号: B50320 产品名称: Anti-PP6C (V/C) pAb 品牌: Agilent 规格:
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
GLO-133-001 PP1C [Protein Phosphatase 1C] (bovine) 品牌 AXXORA
PP1C [Protein Phosphatase 1C] (bovine)
货号: GLO-133-001 产品名称: PP1C [Protein Phosphatase 1C] (bovine) 品牌: AXXORA 规格: 1 ug
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
GLO-135-001 PP2C [Protein Phosphatase 2C] (bovine) 品牌 AXXORA
PP2C [Protein Phosphatase 2C] (bovine)
货号: GLO-135-001 产品名称: PP2C [Protein Phosphatase 2C] (bovine) 品牌: AXXORA 规格: 1 ug
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
ALX-165-022-M001 pp60c-src (521-533) (phosphorylated) 品牌 Alexis
pp60c-src (521-533) (phosphorylated)
货号: ALX-165-022-M001 产品名称: pp60c-src (521-533) (phosphorylated) 品牌: Alexis 规格: 1 mg 三周 生化实验
[pTyr527]pp60c-src (521-533)
This peptide is derived from the C-terminal region of the c-Src protooncogene pp60c-src and binds intramolecularly or intermolecularly to the SH2 domain of the same protein.
Product Specification
Sequence: H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH
Formula: C62H95N16O28P
MW: 1543.5
CAS: 149299-77-4
Purity: ≥98%
Appearance: White lyophilized powder.
Long Term Storage: -20°C
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
ALX-165-022-MC05 pp60c-src (521-533) (phosphorylated) 品牌 Alexis
pp60c-src (521-533) (phosphorylated)
货号: ALX-165-022-MC05 产品名称: pp60c-src (521-533) (phosphorylated) 品牌: Alexis 规格: 0.5 mg 三周 生化实验
[pTyr527]pp60c-src (521-533)
This peptide is derived from the C-terminal region of the c-Src protooncogene pp60c-src and binds intramolecularly or intermolecularly to the SH2 domain of the same protein.
Product Specification
Sequence: H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH
Formula: C62H95N16O28P
MW: 1543.5
CAS: 149299-77-4
Purity: ≥98%
Appearance: White lyophilized powder.
Long Term Storage: -20°C
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
ALX-165-022-M005 pp60c-src (521-533) (phosphorylated) 品牌 Alexis
pp60c-src (521-533) (phosphorylated)
货号: ALX-165-022-M005 产品名称: pp60c-src (521-533) (phosphorylated) 品牌: Alexis 规格: 5 mg 三周 生化实验
[pTyr527]pp60c-src (521-533)
This peptide is derived from the C-terminal region of the c-Src protooncogene pp60c-src and binds intramolecularly or intermolecularly to the SH2 domain of the same protein.
Product Specification
Sequence: H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH
Formula: C62H95N16O28P
MW: 1543.5
CAS: 149299-77-4
Purity: ≥98%
Appearance: White lyophilized powder.
Long Term Storage: -20°C
-20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
07-1224 Anti-PP6C (rabbit polyclonal) 品牌 Millipore
Anti-PP6C (rabbit polyclonal)
货号: 07-1224 产品名称: Anti-PP6C (rabbit polyclonal) 品牌: Millipore 规格: EA 3周到货 生化实验
Anti-PP6C Antibody
Recommended Replacement for: 07-1224 is a recommended replacement for AB4091
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REFERENCES
Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis.
Xiangli Cui,Yu Jin,Deepak Poudyal,Alexander A Chumanevich,Tia Davis,Anthony Windust,Anne Hofseth,Wensong Wu,Joshua Habiger,Edsel Pena,Patricia Wood,Mitzi Nagarkatti,Prakash S Nagarkatti,Lorne Hofseth (2010) Carcinogenesis.31
Species Reactivity Key Applications Host Format Antibody Type
B, H, M, R WB, IP, IH(P) Rabbit Purified Polyclonal Antibody
Description:
Anti-PP6C Antibody
Replaces:
07-1224 is a recommended replacement for AB4091
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Specificity:
Recognizes the catalytic subunit of Protein Phosphatase 6, MW ~33kDa.
Molecular Weight:
Recognizes the catalytic subunit of Protein Phosphatase 6 (PP6), MW ~33kDa.
Immunogen:
The immunogen used to the purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-Ile- Pro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH.
Isotype:
IgG
Background Information:
This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression.
Species Reactivity:
Bovine
Human
Mouse
Rat
Species Reactivity Note:
Bovine; Human; Mouse; Rat
Application Notes:
Immunoprecipitation: A previous lot of this antibody was used in immunoprecipitation at a dilution of 10-20 µg/mL.
Immunohistochemistry(paraffin):
Optimal Staining of PP6 Polyclonal Antibody:
Human Testis
PP6 staining of round spermatids in normal human
testis, tissue pretreated with citrate buffer, pH 6.0.
Antibody was diluted 1:100, using IHC-Select®
detection with HRP-DAB.
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Control:
Jurkat Cell Lysate
Quality Assurance:
Routinely evaluated by Western Blot on Jurkat lysates.
Western Blot Analysis: 1:500 dilution of this lot detected PP6C on 10 μg of Jurkat lysates.
Presentation:
Purified rabbit polyclonal IgG in buffer containing PBS with 0.08% sodium azide.
Storage Conditions:
Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
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UniProt Number:
O00743
Entrez Gene Number:
NM_002721.3
Gene Symbol:
PPP6C
PP6
PPP6
EC 3.1.3.16
Alternate Names:
H.sapiens mRNA for protein phosphatase 6
Serine/threonine-protein phosphatase 6
Protein phosphatase 6, catalytic subunit
Serine/threonine protein phosphatase catalytic subunit
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunoprecipitation
Immunohistochemistry (Paraffin)
Entrez Gene Summary:
This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. The -20°C
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)