OLIG2, RBX, 100UG

货号： AB15328      产品名称： OLIG2, RBX, 100UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Olig2 Antibody
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REFERENCES
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche.
Daniel A Lee,Joseph L Bedont,Thomas Pak,Hong Wang,Juan Song,Ana Miranda-Angulo,Vani Takiar,Vanessa Charubhumi,Francesca Balordi,Hirohide Takebayashi,Susan Aja,Eric Ford,Gordon Fishell,Seth Blackshaw (2012) Nature neuroscience.15
Safety aspects of longitudinal administration of IGF-IIGFBP-3 complex in neonatal mice.
(2011) Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.21:205-11
Safety aspects of longitudinal administration of IGF-I/IGFBP-3 complex in neonatal mice.
Gunnel Hellgren,Wei Han,Xiaoyang Wang,Chatarina Löfqvist,Henrik Hagberg,Carina Mallard,Ann Hellström (2011) Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.21
Species Reactivity Key Applications Host Format Antibody Type
R  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Olig2 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Chemicon (Millipore)
Specificity:
Oligodendrocyte marker Olig2. By Western blot the antibody recognizes a band at ~32 kDa in rat brain extract.
Immunogen:
Synthetic peptide from rat.
Species Reactivity:
Rat
Purification Method:
Immunoaffinity purified
Presentation:
Liquid in PBS containing 0.1% sodium azide.
Storage Conditions:
Maintain at 2-8degC in undiluted aliquots for up to 6 months after date of receipt.
UniProt Number:
Q13516
Entrez Gene Number:
NM_005806.2
Gene Symbol:
OLIG2
bHLHB1
RACK17
OLIGO2
BHLHB1
PRKCBP2
Oligo2
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Entrez Gene Summary:
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
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UniProt Summary:
FUNCTION: SwissProt: Q13516 # Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity).
SIZE: 323 amino acids; 32385 Da
SUBUNIT: Interacts with NKX2-2 (By similarity).
SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2 (By similarity).
TISSUE SPECIFICITY: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, w 2-8℃

OLIG1, RBX-100UG

货号： AB5991      产品名称： OLIG1, RBX-100UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Olig1 Antibody
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REFERENCES
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
Xue, Yuanchao, et al. (2013) Cell, 152: 82-96 (2013)
Human embryonic stem cell-derived oligodendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury.
Keirstead, Hans S, et al. (2005) J. Neurosci., 25: 4694-705 (2005)
Species Reactivity Key Applications Host Format Antibody Type
H, M  ICC, WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Olig1 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Chemicon (Millipore)
Specificity:
Recognizes Olig1. The molecular weight of the protein is 25,430 Daltons.
Molecular Weight:
25.4 kDa
Immunogen:
Synthetic peptide, amino acids 77-91 of Olig1.
Species Reactivity:
Human
Mouse
Application Notes:
Western blot: 1:200-1:1,000 using ECL.
Immunocytochemistry: 1:200-1:1,000.
Optimal working dilutions must be determined by the end user.
Control:
Oligodendrocyte culture, Brain
Purification Method:
Immunoaffinity purified
Presentation:
Affinity Purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Storage Conditions:
Maintain unopened vial at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.
PREPARATION AND USE:
To reconstitute the antibody, centrifuge the antibody vial at moderate speed (5,000 rpm) for 5 minutes to pellet the precipitated antibody product. Carefully remove the ammonium sulfate/PBS buffer solution and discard. It is not necessary to remove all of the ammonium sulfate/PBS solution: 10 μL of residual ammonium sulfate solution will not affect the resuspension of the antibody. Do not let the protein pellet dry, as severe loss of antibody reactivity can occur.
Resuspend the antibody pellet in a suitable biological buffer such as PBS or TBS (pH 7.3-7.5) to a final concentration of 1.0 mg/mL. For example, to achieve a 1.0 mg/mL concentration with 50 μg of precipitated antibody, the amount of buffer needed would be 50 μL.
Carefully add the liquid buffer to the pellet. DO NOT VORTEX. Mix by gentle stirring with a wide pipet tip or gentle finger-tapping. Let the precipitated antibody rehydrate for 1 hour at 4-25°C prior to use. Small particles of precipitated antibody that fail to resuspend are normal. Vials are overfilled to compensate for any losses.
The rehydrated antibody solutions can be stored undiluted at 2-8°C for 2 months without any significant loss of activity. Note, the solution is not sterile, thus care should be taken if product is stored at 2-8°C.
For storage at -20°C, the addition of an equal volume of glycerol can be used, however, it is recommended that ACS grade or higher glycerol be used, as significant loss of activity can occur if the glycerol used is not of high quality.
For long-term storage at -70°C, it is recommended that the rehydrated antibody solution be further diluted 1:1 with a 2% BSA (fraction V, highest-grade available) solution made with the rehydration buffer. The resulting 1% BSA/antibody solution can be aliquoted and stored frozen at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.
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UniProt Number:
Q8TAK6
Entrez Gene Number:
NM_138983.1
Gene Symbol:
OLIG1
BHLHB6
Oligo1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to -70℃

OLIG3, RBX-100UG

货号： AB5995      产品名称： OLIG3, RBX-100UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Olig3 Antibody
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PRODUCT FAMILY INFORMATION
Glial Cell Markers
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
Glial cells, sometimes called neuroglia are non-neuronal cells that maintain homeostasis, form myelin, and provide support and protection for neurons in the brain and peripheral nervous system.
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Species Reactivity Key Applications Host Format Antibody Type
H, M  WB, ICC, IHC Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Olig3 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Chemicon (Millipore)
Specificity:
Recognizes Olig3. The molecular weight of the protein is 27,909 Daltons.
Immunogen:
Synthetic peptide, amino acids 53-66 of Olig3.
Species Reactivity:
Human
Mouse
Application Notes:
Western blot: 1:200-1:1,000 using ECL.
Immunohistochemistry: 1:200-1:1,000.
Immunocytochemistry: 1:200-1:1,000.
Optimal working dilutions must be determined by the end user.
View All »
Presentation:
Affinity purified immunoglobulin. Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.
Storage Conditions:
Maintain unopened vial at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.
PREPARATION AND USE:
To reconstitute the antibody, centrifuge the antibody vial at moderate speed (5,000 rpm) for 5 minutes to pellet the precipitated antibody product. Carefully remove the ammonium sulfate/PBS buffer solution and discard. It is not necessary to remove all of the ammonium sulfate/PBS solution: 10 μL of residual ammonium sulfate solution will not affect the resuspension of the antibody. Do not let the protein pellet dry, as severe loss of antibody reactivity can occur.
Resuspend the antibody pellet in a suitable biological buffer such as PBS or TBS (pH 7.3-7.5) to a final concentration of 1.0 mg/mL. For example, to achieve a 1.0 mg/mL concentration with 50 μg of precipitated antibody, the amount of buffer needed would be 50 μL.
Carefully add the liquid buffer to the pellet. DO NOT VORTEX. Mix by gentle stirring with a wide pipet tip or gentle finger-tapping. Let the precipitated antibody rehydrate for 1 hour at 4-25°C prior to use. Small particles of precipitated antibody that fail to resuspend are normal. Vials are overfilled to compensate for any losses.
The rehydrated antibody solutions can be stored undiluted at 2-8°C for 2 months without any significant loss of activity. Note, the solution is not sterile, thus care should be taken if product is stored at 2-8°C.
For storage at -20°C, the addition of an equal volume of glycerol can be used, however, it is recommended that ACS grade or higher glycerol be used, as significant oss of activity can occur if the glycerol used is not of high quality.
For long-term storage at -70°C, it is recommended that the rehydrated antibody solution be further diluted 1:1 with a 2% BSA (fraction V, highest-grade available) solution made with the rehydration buffer. The resulting 1% BSA/antibody solution can be aliquoted and stored frozen at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.
View All »
UniProt Number:
Q7RTU3
Entrez Gene Number:
NM_175747.2
Gene Symbol:
OLIG3
BHLHB7
bHLHB7
Oligo3
Bhlhb7
View All »
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), o -20℃