Fludarabine Phosphate

货号： 1763-50      产品名称： Fludarabine Phosphate   品牌： Biovision 规格： 50 mg 3周到货 生化实验

Fludarabine Phosphate
An anticancer agent
Product Overview
Product Name: Fludarabine Phosphate
Alternate Name/Synonyms: [(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)- 3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid; Fludara
Description: A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-⍺, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 75607-67-9
Molecular Formula: C₁₀H₁₃FN₅O₇P
Molecular Weight: 365.21
Purity: ≥98%
Solubility:DMSO or H₂O (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)O)O)N=C(N=C2N)F
InChi: InChI=1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5-,6+,9-/m1/s1
InChi Key: GIUYCYHIANZCFB-FJFJXFQQSA-N
PubChem CID: 30751
MDL Number: MFCD00866418
USAGE: For Research Use Only! Not For Use in Humans.

-20°C