Capecitabine

货号： 1741-1000      产品名称： Capecitabine   品牌： Biovision 规格： 1 g 3周到货 生化实验

Capecitabine
A pre-prodrug of 5-fluorouracil
Product Overview
Product Name: Capecitabine
Alternate Name/Synonyms: Pentyl[1-(3,4-dihydroxy-5-methyl-tetrahydrofuran-2-yl)- 5-fluoro-2-oxo-1H-pyrimidin- 4-yl]aminomethanoate; captabin; Ro 09-1978; Xabine
Description: A pre-prodrug of 5-fluorouracil (5-FU).  After oral uptake, capecitabine is first metabolized to 5′-deoxy-5-fluorocytidine (5′-DFCR), which occurs mainly in the liver by carboxyl-esterase.  The metabolite is converted to 5′-deoxy-5-fluoro-uridine (5′-DFUR) by cytidine deaminase in liver and tumor tissue.  Then 5′-DFUR is converted to 5-FU intracellularly by thymidine phosphorylase, which is often expressed in tumor tissue.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 154361-50-9
Molecular Formula: C₁₅H₂₂FN₃O₆
Molecular Weight: 359.35
Purity: ≥99% by HPLC
Solubility:DMSO (100 mg/ml) or EtOH (10 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCCCCOC(=O)NC1=NC(=O)N(C=C1F)C2C(C(C(O2)C)O)O
InChi: InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
InChi Key: GAGWJHPBXLXJQN-UORFTKCHSA-N
PubChem CID: 60953
MDL Number: MFCD00930626
USAGE: For Research Use Only! Not For Use in Humans.

-20°C