D4476

货号： 1770-1      产品名称： D4476   品牌： Biovision 规格： 1 mg 3周到货 生化实验

D4476
A casein kinase (CK) inhibitor
Product Overview
Product Name: D4476
Alternate Name/Synonyms: 4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-(2-pyridinyl) -1H-imidazol-2-yl]benzamide
Description: A cell-permeable, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC₅₀ = 0.3 µM). Also inhibits ALK5 (IC₅₀ = 0.5 µM) and p38ɑMAP kinase (IC₅₀ = 12 µM). Displays selectivity over many other protein kinases.
Peptide Sequence: N/A
Appearance: Off-white solid
Formulation: N/A
CAS Number: 301836-43-1
Molecular Formula: C₂₃H₁₈N₄O₃
Molecular Weight: 398.41
Purity: ≥98% by HPLC
Solubility:DMSO (100 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
InChi: InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)
InChi Key: DPDZHVCKYBCJHW-UHFFFAOYSA-N
PubChem CID: 6419753
MDL Number: MFCD09037526
USAGE: For Research Use Only! Not For Use in Humans.

-20°C