SB 216763

货号： 1769-1      产品名称： SB 216763   品牌： Biovision 规格： 1 mg 3周到货 生化实验

SB 216763
A GSK-3 inhibitor
Product Overview
Product Name: SB 216763
Alternate Name/Synonyms: 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Description: A potent, cell-permeable and ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC₅₀ > 10 μM). Stimulates glycogen synthesis, gene transcription and is neuroprotective.
Peptide Sequence: N/A
Appearance: Orange solid
Formulation: N/A
CAS Number: 280744-09-4
Molecular Formula: C₁₉H₁₂Cl₂N₂O₂
Molecular Weight: 371.22
Purity: ≥98% by HPLC
Solubility:DMSO (50 mM)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl
InChi: InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25)
InChi Key: JCSGFHVFHSKIJH-UHFFFAOYSA-N
PubChem CID: 176158
MDL Number: MFCD09753369
USAGE: For Research Use Only! Not For Use in Humans.

-20°C