H-89 Dihydrochloride

货号： 1768-5      产品名称： H-89 Dihydrochloride   品牌： Biovision 规格： 5 mg 3周到货 生化实验

H-89 Dihydrochloride
A protein kinase A (PKA) inhibitor
Product Overview
Product Name: H-89 Dihydrochloride
Alternate Name/Synonyms: N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-Isoquinolinesulfonamide dihydrochloride
Description: A cell-permeable, ATP-competitive inhibitor of Protein Kinase A (PKA) (IC₅₀ = 50 nM). Also inhibits other kinases, including MSK1 , S6K1 and ROCKII with IC₅₀ values of 120 nM, 80 nM and 270 nM respectively.
Peptide Sequence: N/A
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 127243-85-0
Molecular Formula: C₂₀H₂₀BrN₃O₂S.2HCl
Molecular Weight: 519.28
Purity: ≥98% by HPLC
Solubility:DMSO (200 mg/ml) and H₂O (25 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNCC=CC3=CC=C(C=C3)Br.Cl.Cl
InChi: InChI=1S/C20H20BrN3O2S.2ClH/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20;;/h1-10,12,15,22,24H,11,13-14H2;2*1H/b3-2+;;
InChi Key: GELOGQJVGPIKAM-WTVBWJGASA-N
PubChem CID: 5702541
MDL Number: MFCD11045926
USAGE: For Research Use Only! Not For Use in Humans.

-20°C