标签归档：mutation

4465804   TQMN MUTATION DETECTIONASSAYS   品牌 Invitrogen

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TQMN MUTATION DETECTIONASSAYS

货号： 4465804      产品名称： TQMN MUTATION DETECTIONASSAYS   品牌： Invitrogen 规格： 10 三周到货 生化试验

TaqMan® Mutation Detection Assays detect somatic mutations in genes that are associated with cancer. These research use only assays are powered by competitive allele-specific TaqMan® PCR technology, also known as castPCR™ technology. The castPCR™ technology is highly specific and sensitive, and it can detect rare amounts of mutated DNA in a sample that contains large amounts of normal, wild type DNA.
•High specificity—mutant allele detection is based on an allele-specific primer, while the wild-type background is suppressed by an MGB blocker oligonucleotide
•High sensitivity—assays can detect as low as 0.1% mutant molecules in a background of wild type gDNA as demonstrated in spiking experiments
•Wide dynamic range and excellent PCR efficiency—assays demonstrate at least 4 logs of dynamic range and an average efficiency of 100 ± 10%
•Fast, simple workflow—like other TaqMan® Assays, typically requires 3 hours from sample to results, with minimum hands-on time
•Our current assay set covers 778 assays to key mutation targets in 46 cancer genes

4465807   TQMN MUTATION DETECTION   品牌 Invitrogen

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TQMN MUTATION DETECTION

货号： 4465807      产品名称： TQMN MUTATION DETECTION   品牌： Invitrogen 规格： 10 三周到货 生化试验

TaqMan® Mutation Detection Assays detect somatic mutations in genes that are associated with cancer. These research use only assays are powered by competitive allele-specific TaqMan® PCR technology, also known as castPCR™ technology. The castPCR™ technology is highly specific and sensitive, and it can detect rare amounts of mutated DNA in a sample that contains large amounts of normal, wild type DNA.
•High specificity—mutant allele detection is based on an allele-specific primer, while the wild-type background is suppressed by an MGB blocker oligonucleotide
•High sensitivity—assays can detect as low as 0.1% mutant molecules in a background of wild type gDNA as demonstrated in spiking experiments
•Wide dynamic range and excellent PCR efficiency—assays demonstrate at least 4 logs of dynamic range and an average efficiency of 100 ± 10%
•Fast, simple workflow—like other TaqMan® Assays, typically requires 3 hours from sample to results, with minimum hands-on time
•Our current assay set covers 778 assays to key mutation targets in 46 cancer genes

4467538   TQMN MUTATION DETECTN IPC REA   品牌 Invitrogen

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TQMN MUTATION DETECTN IPC REA

货号： 4467538      产品名称： TQMN MUTATION DETECTN IPC REA   品牌： Invitrogen 规格： KIT 三周到货 生化试验

TaqMan® Mutation Detection IPC Reagent Kit
The TaqMan® Mutation Detection IPC Reagent Kit is a set of optional internal positive control reagents that can be duplexed with any TaqMan® Mutation Detection assay to provide a positive PCR control result. The IPC reagents can distinguish a mutation target negative result from a PCR failure result. The TaqMan® Mutation Detection IPC Reagent Kit is preoptimized for use with the TaqMan® Mutation Detection Assays. The IPC reagents can be duplexed with any TaqMan® Mutation Detection Assay and gDNA sample, without compromising the mutation detection assay reaction efficiency. This feature allows the mutation detection assays to detect low copies of mutated DNA in the presence of a robust PCR-positive signal from the IPC reagents.
Product Overview
The TaqMan® Mutation Detection IPC Reagent Kit includes:
50X Exogenous IPC template DNA (200 µL)
A synthetic template that contains the exogenous, non-human DNA target for the assay
Species: Non-Human 
Includes: Control Primer-Probe Set(s) & Template(s) 
Platform: StepOnePlus™,
7500 Fast System,
7500 System,
ViiA™ 7 System 
Target Gene: exogeneous, non-human DNA target 
Control Type: Positive Control 
Label or Dye: VIC®,
TAMRA™ 
Product Size: 1 kit
Control Template: non-human DNA 
Detection Method: Primer-Probe Detection 
Sample Type (General): Cells,
FFPE & Fixed Samples,
DNA 
Shipping Condition: Dry Ice
Store at –15°C to –25° C, protected from light. Minimize freeze-thaw cycles.