Anti-Megf10

货号： ABC10      产品名称： Anti-Megf10   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-Megf10 Antibody
Species Reactivity Key Applications Host Format Antibody Type
M  WB, IF Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Megf10 Antibody
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Specificity:
This antibody recognizes Megf10 at the cytoplasmic domain.
Molecular Weight:
~130 kDa observed
Epitope:
Cytoplasmic domain
Immunogen:
Histidine-tagged recombinant protein corresponding to the cytoplasmic domain of mouse Megf10.
Background Information:
Multiple epidermal growth factor-like domains protein 10 (Megf10) is a type 1 transmembrane protein with multiple EGF-like extracellular domains. Megf10 is highly expressed in the brain, and plays an important role in phacocytosis of apoptotic cells. This role may be performed through the interaction of Megf10 with the ATP-binding cassette transporter (ABCA1) protein. Previous studies have suggested that Megf10 may be involved in the uptake of amyloid β peptides in the brain. Megf10 may therefore play a role Alzheimer’s disease.
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Species Reactivity:
Mouse
Species Reactivity Note:
Demonstrated to react with Mouse. Other homologies: Rat (98% sequence homology) and Human (92% sequence homology).
Application Notes:
Immunofluorescence Analysis: A representative lot was used by an independent laboratory in P7 caudal brain tissue and retina cells. Image courtesy from the laboratory of Dr. Joshua Sanes, Harvard University.
Control:
Mouse retina tissue lysate
Quality Assurance:
Evaluated by Western Blot in mouse retina tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Megf10 on 10 µg of mouse retina tissue lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q6DIB5
Entrez Gene Number:
NP_001001979
Gene Symbol:
Megf10
Alternate Names:
Multiple epidermal growth factor-like domains protein 10
Multiple EGF-like domains protein 10
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunofluorescence
Product Name:
Anti-Megf10 Antibody
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect the Megf10 protein using this Anti-Megf10 validated for use in WB & IF.

2-8℃