标签归档：pt

pt-ctr2   PlasmoTest Controls   品牌 Invivogen

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PlasmoTest Controls

货号： pt-ctr2      产品名称： PlasmoTest Controls   品牌： Invivogen 规格： 200 tests 二周到货 生化试验

PlasmoTest™ Controls
Positive and Negative Controls for 200 tests with the mycoplasma detection kit PlasmoTest™.
Provided lyophilized
Shipped at room temperature

rep-pt2   PlasmoTest   品牌 Invivogen

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PlasmoTest

货号： rep-pt2      产品名称： PlasmoTest   品牌： Invivogen 规格： 1 kit (500 samples) 二周到货 生化试验

PlasmoTest™
PlasmoTest™ provides a simple, rapid and reliable assay for the visual detection of mycoplasma contamination in cell cultures. This assay is the first to utilize cells to signal the presence of mycoplasma.
PlasmoTest™ features two major constituents: the Mycoplasma sensor cells and the HEK-Blue™ Detection medium.
The Mycoplasma sensor cells detect the presence of mycoplasmas leading to a color change of the HEK-Blue™ Detection medium. The Mycoplasma sensor cells recognize mycoplasmas through Toll-like Receptor 2 (TLR2), a pathogen recognition receptor. In the presence of mycoplasmas, TLR2 initiates a signaling cascade leading to the activation of NF-kB and other transcription factors. These transcription factors induce the secretion of SEAP (secreted embryonic alkaline phosphatase) in the supernatant which is readily detected by the purple/blue coloration of the HEK-Blue™ Detection medium.
• Requires only basic cell culture knowledge
• Hands-on time less than 1 hour. Gives results after overnight incubation
• Detects all cell culture contaminants
• Detects 5.102-5.105 cfu/ml mycoplasmas
• No false positive: a positive result indicates the presence of a cell culture contaminant
• Available in two quantities :
– Kit rep-pt1 : test up to 250 samples
– Kit rep-pt2 : test up to 500 samples
To perform further assays, only the reagents need to be reordered.

tlrl-pt17   Poly(dT)   品牌 Invivogen

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Poly(dT)

货号： tlrl-pt17      产品名称： Poly(dT)   品牌： Invivogen 规格： 100 nmol 二周到货 生化试验

Poly(dT)
Poly(dT), a thymidine homopolymer phosphorothioate ODN, is a modulator of human TLR7 and TLR8. In combination with an imidazoquinoline, such as R848 and CL075, it increases TLR8-mediated signaling but abolishes TLR7-mediated signaling [1, 2]. Alone poly(dT) has no significant effect on either of these TLRs. Furthermore, co-incubation of poly(dT) and an imidazoquinoline was shown to induce NF-κB activation in HEK293 cells transfected with murine TLR8- and primary TLR8-expressing mouse cells, demonstrating that murine TLR8 is functional [3].
Specificity: TLR7/8 modulator
Working Concentration: 10 μM
Endotoxin level:  EndoFit™ (<0.001 EU/µg)
Solubility: 100 nmol/ml in water

516569-10MG   PPARb/d Antagonist, PT-S58   品牌 Merck

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PPARb/d Antagonist, PT-S58

货号： 516569-10MG      产品名称： PPARb/d Antagonist, PT-S58   品牌： Merck 规格： *** 3周到货 生化实验

PPARβ/δ Antagonist, PT-S58
PPARβ Antagonist II, methyl 3-(N-(4-(tert-butylamino)-2-methoxyphenyl)sulfamoyl)thiophene-2-carboxylate, PPARδ Antagonist II
A cell-permeable, diaryl sulfonamide PPARβ/δ subtype-specific pure competitive antagonist with an IC50 of 98 nM. Antagonizes ligand binding without enabling coregulator interactions. Inhibits the PPARβ/δ specific agonist-induced transcriptional activity in cell cultures.
产品信息
Form  Dark yellow solid
Protect from Light  是的
Packaged under inert gas  是的
Purity  ≥98% by HPLC
Solubility  DMSO
Chemical formula  C17H22N2O5S2
商店和运输信息
Storage  -20°C
Ship  Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Standard Handling

-20°C

rep-pt1   PlasmoTest   品牌 Invivogen

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PlasmoTest

货号： rep-pt1      产品名称： PlasmoTest   品牌： Invivogen 规格： 1 kit (250 samples) 二周到货 生化试验

PlasmoTest™
PlasmoTest™ provides a simple, rapid and reliable assay for the visual detection of mycoplasma contamination in cell cultures. This assay is the first to utilize cells to signal the presence of mycoplasma.
PlasmoTest™ features two major constituents: the Mycoplasma sensor cells and the HEK-Blue™ Detection medium.
The Mycoplasma sensor cells detect the presence of mycoplasmas leading to a color change of the HEK-Blue™ Detection medium. The Mycoplasma sensor cells recognize mycoplasmas through Toll-like Receptor 2 (TLR2), a pathogen recognition receptor. In the presence of mycoplasmas, TLR2 initiates a signaling cascade leading to the activation of NF-kB and other transcription factors. These transcription factors induce the secretion of SEAP (secreted embryonic alkaline phosphatase) in the supernatant which is readily detected by the purple/blue coloration of the HEK-Blue™ Detection medium.
• Requires only basic cell culture knowledge
• Hands-on time less than 1 hour. Gives results after overnight incubation
• Detects all cell culture contaminants
•Detects 5.102-5.105 cfu/ml mycoplasmas
• No false positive: a positive result indicates the presence of a cell culture contaminant
• Available in two quantities :
– Kit rep-pt1 : test up to 250 samples
– Kit rep-pt2 : test up to 500 samples
To perform further assays, only the reagents need to be reordered.