36000   Screen Quest Membrane Potential Assay Kit *Orange Fluorescence*   品牌 AAT

Screen Quest Membrane Potential Assay Kit *Orange Fluorescence*

货号: 36000      产品名称: Screen Quest Membrane Potential Assay Kit *Orange Fluorescence*   品牌: AAT 规格: 10 plates 二周到货 生化试验

Screen Quest� Membrane Potential Assay Kit *Orange Fluorescence*
Cat # 36000
Storage F/D/L (see storage codes below)
Unit Size 10 plates
Ex (nm) 535
Em (nm) 560
Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used for transmitting signals between different parts of a cell. Opening or closing of ion channels at one point in the membrane produces a local change in the membrane potential, which causes electric current to flow rapidly to other points in the membrane. Ion channels have been identified as important drug discovery targets. Our Screen Quest� Membrane Potential Assay Kit is a homogeneous assay with fast read time. It uses our proprietary long wavelength membrane potential indicator to detect the membrane potential change that is caused by the opening and closing of the ion channels. The red fluorescence of the membrane potential indicator used in the kit has enhanced fluorescence upon entering cells and minimizes the interferences resulted from the screening compounds and/or cellular autofluorescence.  
Detailed Information:   Protocol      References      MSDS
Related Products:     Membrane Potentials 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

 

 

 

36001   Screen Quest Membrane Potential Assay Kit *Orange Fluorescence*   品牌 AAT

Screen Quest Membrane Potential Assay Kit *Orange Fluorescence*

货号: 36001      产品名称: Screen Quest Membrane Potential Assay Kit *Orange Fluorescence*   品牌: AAT 规格: 100 plates 二周到货 生化试验

Screen Quest� Membrane Potential Assay Kit *Orange Fluorescence*
Cat # 36001
Storage F/D/L (see storage codes below)
Unit Size 100 plates
Ex (nm) 535
Em (nm) 560
Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used for transmitting signals between different parts of a cell. Opening or closing of ion channels at one point in the membrane produces a local change in the membrane potential, which causes electric current to flow rapidly to other points in the membrane. Ion channels have been identified as important drug discovery targets. Our Screen Quest� Membrane Potential Assay Kit is a homogeneous assay with fast read time. It uses our proprietary long wavelength membrane potential indicator to detect the membrane potential change that is caused by the opening and closing of the ion channels. The red fluorescence of the membrane potential indicator used in the kit has enhanced fluorescence upon entering cells and minimizes the interferences resulted from the screening compounds and/or cellular autofluorescence.  
Detailed Information:   Protocol      References      MSDS
Related Products:     Membrane Potentials 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

AB15560-50UL   TRANSIENT RECEPTOR POTENTIAL CHANNEL 1, RBX-50UL   品牌 Millipore

TRANSIENT RECEPTOR POTENTIAL CHANNEL 1, RBX-50UL

货号: AB15560-50UL      产品名称: TRANSIENT RECEPTOR POTENTIAL CHANNEL 1, RBX-50UL   品牌: Millipore 规格: EA 三周到货 生化实验

Anti-TRPM1 Antibody
Species Reactivity Key Applications Host Format Antibody Type
H  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-TRPM1 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Chemicon (Millipore)
Specificity:
Recognizes TRPM1.
Immunogen:
Purified peptide from the C-terminus of human TRPM1 (Accession number O75560).
Species Reactivity:
Human
Application Notes:
Western blot: 1:200-1:500 using ECL on human A875 melanoma cell line lysate.
Dilutions should be made using a carrier protein such as BSA (1-3%).
Optimal working dilutions must be determined by the end user.
Control:
Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
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Purification Method:
Immunoaffinity purified
Presentation:
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.05% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
Storage Conditions:
Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
UniProt Number:
O75560
Entrez Gene Number:
NM_002420.4
Gene Symbol:
TRPM1
Melastatin-1
MLSN1
LTRPC1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Entrez Gene Summary:
The protein encoded by this gene is similar to the transient receptor potential (Trp) calcium channel family members. The expression of this protein is inversely correlated with melanoma aggressiveness, suggesting that it suppresses melanoma metastasis.
UniProt Summary:
SIZE: 1533 amino acids; 174432 Da
Brand Family:
Chemicon
Product Name:
Anti-TRPM1 Antibody
Antibody Type:
Polyclonal Antibody
Qty/Pk:
50 µL
Format:
Affinity Purified
Host:
Rabbit
Applications:
Detect TRPM1 using this Anti-TRPM1 Antibody validated for use in WB.

-20℃

36005   Screen Quest Membrane Potential Assay Kit *Red Fluorescence*   品牌 AAT

Screen Quest Membrane Potential Assay Kit *Red Fluorescence*

货号: 36005      产品名称: Screen Quest Membrane Potential Assay Kit *Red Fluorescence*   品牌: AAT 规格: 10 plates 二周到货 生化试验

Screen Quest� Membrane Potential Assay Kit *Red Fluorescence*
Cat # 36005
Storage F/D/L (see storage codes below)
Unit Size 10 plates
Ex (nm) 635
Em (nm) 660 
Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used for transmitting signals between different parts of a cell. Opening or closing of ion channels at one point in the membrane produces a local change in the membrane potential, which causes electric current to flow rapidly to other points in the membrane. Ion channels have been identified as important drug discovery targets. Our Screen Quest� Membrane Potential Assay Kit is a homogeneous assay with fast read time. It uses our proprietary long wavelength membrane potential indicator to detect the membrane potential change that is caused by the opening and closing of the ion channels. The red fluorescence of the membrane potential indicator used in the kit has enhanced fluorescence upon entering cells and minimizes the interferences resulted from the screening compounds and/or cellular autofluorescence.  
Detailed Information:   Protocol      References      MSDS
Related Products:     Membrane Potentials 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)

36006   Screen Quest Membrane Potential Assay Kit *Red Fluorescence*   品牌 AAT

Screen Quest Membrane Potential Assay Kit *Red Fluorescence*

货号: 36006      产品名称: Screen Quest Membrane Potential Assay Kit *Red Fluorescence*   品牌: AAT 规格: 100 plates 二周到货 生化试验

Screen Quest� Membrane Potential Assay Kit *Red Fluorescence*
Cat # 36006
Storage F/D/L (see storage codes below)
Unit Size 100 plates
Ex (nm) 635
Em (nm) 660
Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used for transmitting signals between different parts of a cell. Opening or closing of ion channels at one point in the membrane produces a local change in the membrane potential, which causes electric current to flow rapidly to other points in the membrane. Ion channels have been identified as important drug discovery targets. Our Screen Quest� Membrane Potential Assay Kit is a homogeneous assay with fast read time. It uses our proprietary long wavelength membrane potential indicator to detect the membrane potential change that is caused by the opening and closing of the ion channels. The red fluorescence of the membrane potential indicator used in the kit has enhanced fluorescence upon entering cells and minimizes the interferences resulted from the screening compounds and/or cellular autofluorescence.  
Detailed Information:   Protocol      References      MSDS
Related Products:     Membrane Potentials 
Storage Codes:
  D = Desiccated
  L = Avoid light
  F = Freeze (<-15 癈)
  R = Refrigerated (2-4 癈)
  RT = Room temperature (4-50 癈)