MT5-MMP CATALYTIC DOMAIN, HIS-TAG, REC.

货号： PF117-10UG      产品名称： MT5-MMP CATALYTIC DOMAIN, HIS-TAG, REC.   品牌： Merck 规格： *** 3周到货 生化实验

MT5-MMP, Catalytic Domain, His•Tag®, Human, Recombinant, E. coli
MMP-24, Catalytic Domain
Recombinant, human pro-MT5-MMP fused to a His•Tag® sequence, expressed in E. coli and activated to yield the active catalytic domain. Two isoforms are produced, one with an N-terminal Tyr156, the other with an N-terminal Leu158. Useful for the study of the activation of progelatinase A and the degradation of extracellular matrix proteins. MT5-MMP is a member of the Zn2+- and Ca2+-dependent endopeptidases that functions in the degradation of extracellular matrix components such as gelatin, chondroitin sulfate, and dermatan sulfate. It has a tendency to be shed from cell surface membranes and appears to undergo rapid autocatalytic destruction into smaller fragments.
产品信息
Form  Liquid
Formulation  In 150 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl2, pH 7.5.
Preservative  None
Molar mass  22,000
Avoid freeze/thaw  是的
Specific activity  ≥100 mU/mg protein
Unit definition  One unit is defined as the amount of enzyme necessary to hydrolyze 1.0 μmol of the substrate MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg (Cat. No. 03-32-5032) per minute at 37°C, pH 7.5.
Purity  ≥95% by SDS-PAGE
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling

≤ -70°C