IL-1 RA, human recombinant

货号： 4263-100      产品名称： IL-1 RA, human recombinant   品牌： Biovision 规格： 100 μg 3周到货 生化实验

IL-1RA, human recombinant
A natural inhibitor of the pro-inflammatory effect of IL1β
Product Overview
Alternate Name/Synonyms: IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430, human IL-1RA, recombinnat human IL-1RA
Gene Symbol: IL-1RA
Accession #: P18510
Gene ID: 3557
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized without additives
Molecular Weight: 17.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: N/A
Biological Activity: The ED₅₀ as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5 ng/ml
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers
Storage Temp.: -20°C
Shipping: Blue Ice
Background Information: Interleukin-1 RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1-alpha (IL1A) and interleukin 1-beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. IL1RA Human Recombinant produced in E.Coli is a non-glycosylated, N-terminal methionyl form of the human naturally-occurring polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton. The IL1RA is purified by proprietary chromatographic techniques
Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Arg-Pro-Ser-Gly
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

IL-1 RA, human recombinant

货号： 4263-1000      产品名称： IL-1 RA, human recombinant   品牌： Biovision 规格： 1 mg 3周到货 生化实验

IL-1RA, human recombinant
A natural inhibitor of the pro-inflammatory effect of IL1β
Product Overview
Alternate Name/Synonyms: IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430, human IL-1RA, recombinnat human IL-1RA
Gene Symbol: IL-1RA
Accession #: P18510
Gene ID: 3557
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized without additives
Molecular Weight: 17.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: N/A
Biological Activity: The ED₅₀ as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5 ng/ml
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers
Storage Temp.: -20°C
Shipping: Blue Ice
Background Information: Interleukin-1 RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1-alpha (IL1A) and interleukin 1-beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. IL1RA Human Recombinant produced in E.Coli is a non-glycosylated, N-terminal methionyl form of the human naturally-occurring polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton. The IL1RA is purified by proprietary chromatographic techniques
Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Arg-Pro-Ser-Gly
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-20°C

IL-1 RA, human recombinant

货号： 4263-20      产品名称： IL-1 RA, human recombinant   品牌： Biovision 规格： 20 μg 3周到货 生化实验

IL-1RA, human recombinant
A natural inhibitor of the pro-inflammatory effect of IL1β
Product Overview
Alternate Name/Synonyms: IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430, human IL-1RA, recombinnat human IL-1RA
Gene Symbol: IL-1RA
Accession #: P18510
Gene ID: 3557
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Lyophilized without additives
Molecular Weight: 17.0 kDa
Purity by SDS-PAGE: ≥98%
Purity by HPLC: ≥98%
Endotoxin Level: N/A
Biological Activity: The ED₅₀ as determined by the dose-dependent inhibition of IL-1 stimulation of D10S cells was found to be 0.5 ng/ml
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile H₂O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers
Storage Temp.: -20°C
Shipping: Blue Ice
Background Information: Interleukin-1 RA is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1-alpha (IL1A) and interleukin 1-beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. IL1RA Human Recombinant produced in E.Coli is a non-glycosylated, N-terminal methionyl form of the human naturally-occurring polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton. The IL1RA is purified by proprietary chromatographic techniques
Amino Acid Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Arg-Pro-Ser-Gly
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-20°C