标签归档：dusp

6371-100   Human Recombinant DUSP3   品牌 Biovision

发表于由

Human Recombinant DUSP3

货号： 6371-100      产品名称： Human Recombinant DUSP3   品牌： Biovision 规格： 100 μg 3周到货 生化实验

Human Recombinant DUSP3
Negatively regulates MAPK superfamily members
Product Overview
Product Name: Human Recombinant DUSP3
Alternate Name/Synonyms: Dual specificity protein phosphatase 3, VHR.
Gene Symbol: DUSP3
Accession #: P51452
Gene ID: 1845
Source: E. coli
Appearance: Liquid
Physical Form Description: 1 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2 mM DTT and 0.15 M NaCl.
Molecular Weight: 22.6 kDa (205 aa, 1-185 aa + NT His-Tag)
Purity by SDS-PAGE: ≥95%
Purity by HPLC: N/A
Endotoxin Level: N/A
Biological Activity: Specific activity: >1750 units/mg.
Reconstitution Instructions: N/A
Storage Temp.: -80°C
Shipping: Gel pack
Background Information: DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2.
Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE GKLKP
Handling: Centrifuge the vial prior to opening
USAGE: For Research Use Only! Not For Use in Humans.

-80°C