标签归档：camptothecin

C0150-500 mg   Camptothecin   品牌 LKT

发表于由

Camptothecin

货号： C0150-500 mg      产品名称： Camptothecin   品牌： LKT 规格： 500 mg 三周到货 生化试验

Description
A cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications 
Cas No. 7689-03-4
Product ID  C0150
Product Name  Camptothecin
Chemical Name  (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 348.35
Melting Point 264oC-267oC(dec.)
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
Ship Temp Ambient
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).

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C0152-1 mg   Camptothecin, 9-amino   品牌 LKT

发表于由

Camptothecin, 9-amino

货号： C0152-1 mg      产品名称： Camptothecin, 9-amino   品牌： LKT 规格： 1 mg 三周到货 生化试验

Camptothecin, 9-amino
Description
The derivitives of camptothecin, such as 9-amino-camptothecin, have been shown to inhibit topoisomerase I. These compounds may also induce the expression of certain protooncogenes in human leukemia cells.
Specifications 
Cas No. 91421-43-1
Product ID  C0152
Product Name  Camptothecin, 9-amino
Synonym 9-Amino-20-camptothecin; 9-AC
Formula Wt. 363.37
Melting Point =300%
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
References Kharbanda, S.; Rubin, E.; Gunji, H.; Hinz, H.; Giovanella, B.; Pantazis, P.; Kufe, D. Cancer Res. 51:6636-6642 (1991).
 

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C0150-100 mg   Camptothecin   品牌 LKT

发表于由

Camptothecin

货号： C0150-100 mg      产品名称： Camptothecin   品牌： LKT 规格： 100 mg

Description
A cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications 
Cas No. 7689-03-4
Product ID  C0150
Product Name  Camptothecin
Chemical Name  (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 348.35
Melting Point 264oC-267oC(dec.)
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
Ship Temp Ambient
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).

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C0150-25 mg   Camptothecin   品牌 LKT

发表于由

Camptothecin

货号： C0150-25 mg      产品名称： Camptothecin   品牌： LKT 规格： 25 mg

Description
A cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications 
Cas No. 7689-03-4
Product ID  C0150
Product Name  Camptothecin
Chemical Name  (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 348.35
Melting Point 264oC-267oC(dec.)
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
Ship Temp Ambient
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).

-20oC

C0150-250 mg   Camptothecin   品牌 LKT

发表于由

Camptothecin

货号： C0150-250 mg      产品名称： Camptothecin   品牌： LKT 规格： 250 mg

Description
A cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications 
Cas No. 7689-03-4
Product ID  C0150
Product Name  Camptothecin
Chemical Name  (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino- [1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 348.35
Melting Point 264oC-267oC(dec.)
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
Ship Temp Ambient
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).

-20oC

C0152-10 mg   Camptothecin, 9-amino   品牌 LKT

发表于由

Camptothecin, 9-amino

货号： C0152-10 mg      产品名称： Camptothecin, 9-amino   品牌： LKT 规格： 10 mg 三周到货 生化试验

Camptothecin, 9-amino    
Description
The derivitives of camptothecin, such as 9-amino-camptothecin, have been shown to inhibit topoisomerase I. These compounds may also induce the expression of certain protooncogenes in human leukemia cells.
Specifications 
Cas No. 91421-43-1
Product ID  C0152
Product Name  Camptothecin, 9-amino
Synonym 9-Amino-20-camptothecin; 9-AC
Formula Wt. 363.37
Melting Point =300%
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
References Kharbanda, S.; Rubin, E.; Gunji, H.; Hinz, H.; Giovanella, B.; Pantazis, P.; Kufe, D. Cancer Res. 51:6636-6642 (1991).
 

-20oC

C0152-25 mg   Camptothecin, 9-amino   品牌 LKT

发表于由

Camptothecin, 9-amino

货号： C0152-25 mg      产品名称： Camptothecin, 9-amino   品牌： LKT 规格： 25 mg 三周到货 生化试验

Camptothecin, 9-amino     
Description
The derivitives of camptothecin, such as 9-amino-camptothecin, have been shown to inhibit topoisomerase I. These compounds may also induce the expression of certain protooncogenes in human leukemia cells.
Specifications 
Cas No. 91421-43-1
Product ID  C0152
Product Name  Camptothecin, 9-amino
Synonym 9-Amino-20-camptothecin; 9-AC
Formula Wt. 363.37
Melting Point =300%
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
References Kharbanda, S.; Rubin, E.; Gunji, H.; Hinz, H.; Giovanella, B.; Pantazis, P.; Kufe, D. Cancer Res. 51:6636-6642 (1991).
 

-20oC

C0152-50 mg   Camptothecin, 9-amino   品牌 LKT

发表于由

Camptothecin, 9-amino

货号： C0152-50 mg      产品名称： Camptothecin, 9-amino   品牌： LKT 规格： 50 mg 三周到货 生化试验

Camptothecin, 9-amino      
Description
The derivitives of camptothecin, such as 9-amino-camptothecin, have been shown to inhibit topoisomerase I. These compounds may also induce the expression of certain protooncogenes in human leukemia cells.
Specifications 
Cas No. 91421-43-1
Product ID  C0152
Product Name  Camptothecin, 9-amino
Synonym 9-Amino-20-camptothecin; 9-AC
Formula Wt. 363.37
Melting Point =300%
Purity ≥98% 
Solubility Soluble in DMSO.
Store Temp -20oC
References Kharbanda, S.; Rubin, E.; Gunji, H.; Hinz, H.; Giovanella, B.; Pantazis, P.; Kufe, D. Cancer Res. 51:6636-6642 (1991).
 

 

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C0154-10 mg   Camptothecin, 7-ethyl-10-hydroxy (SN-38)   品牌 LKT

发表于由

Camptothecin, 7-ethyl-10-hydroxy (SN-38)

货号： C0154-10 mg      产品名称： Camptothecin, 7-ethyl-10-hydroxy (SN-38)   品牌： LKT 规格： 10 mg 三周到货 生化试验

Camptothecin, 7-ethyl-10-hydroxy (SN-38)      
Description
The active metablite of irinotecan, a topoisomerase I inhibitor.
Specifications 
Cas No. 86639-52-3
Product ID  C0154
Product Name  Camptothecin, 7-ethyl-10-hydroxy (SN-38)
Chemical Name  4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3′,4′:6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Synonym SN-38; 7-ethyl-10-hydroxy-CPT
Formula Wt. 392.4
Melting Point 228oC-235oC
Purity ≥98% 
Stability Protect from light.
Store Temp -20oC
References Kaneda N. Nagata H. Furuta T. Yokokura T. Cancer Research. 50:1715-20, (1990).
 

-20oC

C0154-100 mg   Camptothecin, 7-ethyl-10-hydroxy (SN-38)   品牌 LKT

发表于由

Camptothecin, 7-ethyl-10-hydroxy (SN-38)

货号： C0154-100 mg      产品名称： Camptothecin, 7-ethyl-10-hydroxy (SN-38)   品牌： LKT 规格： 100 mg 三周到货 生化试验

Camptothecin, 7-ethyl-10-hydroxy (SN-38)      
Description
The active metablite of irinotecan, a topoisomerase I inhibitor.
Specifications 
Cas No. 86639-52-3
Product ID  C0154
Product Name  Camptothecin, 7-ethyl-10-hydroxy (SN-38)
Chemical Name  4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3′,4′:6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Synonym SN-38; 7-ethyl-10-hydroxy-CPT
Formula Wt. 392.4
Melting Point 228oC-235oC
Purity ≥98% 
Stability Protect from light.
Store Temp -20oC
References Kaneda N. Nagata H. Furuta T. Yokokura T. Cancer Research. 50:1715-20, (1990).
 

-20oC

C0154-50 mg   Camptothecin, 7-ethyl-10-hydroxy (SN-38)   品牌 LKT

发表于由

Camptothecin, 7-ethyl-10-hydroxy (SN-38)

货号： C0154-50 mg      产品名称： Camptothecin, 7-ethyl-10-hydroxy (SN-38)   品牌： LKT 规格： 50 mg 三周到货 生化试验

Camptothecin, 7-ethyl-10-hydroxy (SN-38)       
Description
The active metablite of irinotecan, a topoisomerase I inhibitor.
Specifications 
Cas No. 86639-52-3
Product ID  C0154
Product Name  Camptothecin, 7-ethyl-10-hydroxy (SN-38)
Chemical Name  4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3′,4′:6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Synonym SN-38; 7-ethyl-10-hydroxy-CPT
Formula Wt. 392.4
Melting Point 228oC-235oC
Purity ≥98% 
Stability Protect from light.
Store Temp -20oC
References Kaneda N. Nagata H. Furuta T. Yokokura T. Cancer Research. 50:1715-20, (1990).
 

 

-20oC

C0155-100 mg   Camptothecin, 10-hydroxy   品牌 LKT

发表于由

Camptothecin, 10-hydroxy

货号： C0155-100 mg      产品名称： Camptothecin, 10-hydroxy   品牌： LKT 规格： 100 mg

Description
A potent cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications 
Cas No. 19685-09-7
Product ID  C0155
Product Name  Camptothecin, 10-hydroxy
Chemical Name  (S)-4-Ethyl-4,10-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 364.35
Melting Point 268oC-270oC
Purity ≥96% 
Solubility Soluble in DMSO.
Store Temp -20oC
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).
 

-20oC

C0155-25 mg   Camptothecin, 10-hydroxy   品牌 LKT

发表于由

Camptothecin, 10-hydroxy

货号： C0155-25 mg      产品名称： Camptothecin, 10-hydroxy   品牌： LKT 规格： 25 mg

Description
A potent cytotoxic agent, which inhibits DNA topoisomerase I, induces strand breaks in chromosomal DNA and induces apoptosis.
Specifications 
Cas No. 19685-09-7
Product ID  C0155
Product Name  Camptothecin, 10-hydroxy
Chemical Name  (S)-4-Ethyl-4,10-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Formula Wt. 364.35
Melting Point 268oC-270oC
Purity ≥96% 
Solubility Soluble in DMSO.
Store Temp -20oC
References Hertzberg, R.P., Caranfa, M.J., Hecht, S.M. Biochemistry. 28:4629-4638 (1989). Cotter, T.G., Glynn, J.M., Echeverri, F., Green, D.R. Anticancer Res. 12:773-9 (1992).
 

-20oC

C0156-100 mg   Camptothecin, 9-nitro-20(S)   品牌 LKT

发表于由

Camptothecin, 9-nitro-20(S)

货号： C0156-100 mg      产品名称： Camptothecin, 9-nitro-20(S)   品牌： LKT 规格： 100 mg 三周到货 生化试验

Camptothecin, 9-nitro-20(S)      
Description
Active derivative of camptothecin. Induces apoptosis and inhibits HIV.
Specifications 
Cas No. 91421-42-0
Product ID  C0156
Product Name  Camptothecin, 9-nitro-20(S)
Chemical Name  9-Nitro-20(S)-Camptothecin
Synonym Rubitecan, 9-nitrocamptothecin, 9-nitro-CPT
Formula Wt. 393.35
Melting Point 182
Purity ≥98% 
Store Temp -20oC
References Chatterjee D. Schmitz I. Krueger A. et al Cancer Res. 61:7148-54 (2001). Hung CL. Doniger J. Palini A. et al. J Med Virology. 64:238-44 (2001).
 

-20oC

C0156-25 mg   Camptothecin, 9-nitro-20(S)   品牌 LKT

发表于由

Camptothecin, 9-nitro-20(S)

货号： C0156-25 mg      产品名称： Camptothecin, 9-nitro-20(S)   品牌： LKT 规格： 25 mg 三周到货 生化试验

Camptothecin, 9-nitro-20(S)      
Description
Active derivative of camptothecin. Induces apoptosis and inhibits HIV.
Specifications 
Cas No. 91421-42-0
Product ID  C0156
Product Name  Camptothecin, 9-nitro-20(S)
Chemical Name  9-Nitro-20(S)-Camptothecin
Synonym Rubitecan, 9-nitrocamptothecin, 9-nitro-CPT
Formula Wt. 393.35
Melting Point 182
Purity ≥98% 
Store Temp -20oC
References Chatterjee D. Schmitz I. Krueger A. et al Cancer Res. 61:7148-54 (2001). Hung CL. Doniger J. Palini A. et al. J Med Virology. 64:238-44 (2001).
 

-20oC

C0156-50 mg   Camptothecin, 9-nitro-20(S)   品牌 LKT

发表于由

Camptothecin, 9-nitro-20(S)

货号： C0156-50 mg      产品名称： Camptothecin, 9-nitro-20(S)   品牌： LKT 规格： 50 mg 三周到货 生化试验

Camptothecin, 9-nitro-20(S)     
Description
Active derivative of camptothecin. Induces apoptosis and inhibits HIV.
Specifications 
Cas No. 91421-42-0
Product ID  C0156
Product Name  Camptothecin, 9-nitro-20(S)
Chemical Name  9-Nitro-20(S)-Camptothecin
Synonym Rubitecan, 9-nitrocamptothecin, 9-nitro-CPT
Formula Wt. 393.35
Melting Point 182
Purity ≥98% 
Store Temp -20oC
References Chatterjee D. Schmitz I. Krueger A. et al Cancer Res. 61:7148-54 (2001). Hung CL. Doniger J. Palini A. et al. J Med Virology. 64:238-44 (2001).
 

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ALX-350-015-M050   (S)-(+)-Camptothecin   品牌 Alexis

发表于由

(S)-(+)-Camptothecin

货号： ALX-350-015-M050      产品名称： (S)-(+)-Camptothecin   品牌： Alexis 规格： 50 mg 3周到货 生化实验

(S)-(+)-Camptothecin
Potent antitumor agent
Potent antitumor agent. Inhibitor of DNA-topoisomerase I. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cells. Inhinbits Tat-mediated transactivation of HIV-1. Induces apoptosis in osteosarcoma and hepatoma cells. Suppresses nitric oxide (NO) biosynthesis.
Product Specification
Formula: C20H16N2O4
MW: 348.4
Source: Isolated from Mappia foetida Miers (Nothapodytes foetida (Wt.) Sleumer).
CAS: 7689-03-4
MI: 14: 1735
RTECS: UQ0492000
Purity: ≥98% (HPLC)
Appearance: Pale yellow powder.
Hazard: TOXIC.
Solubility: Soluble in DMSO (10mg/ml), methanol (40mg/ml), 0.1N sodium hydroxide (50mg/ml) or acetic acid; insoluble in water.
Long Term Storage: +4°C
Handling: Protect from light and moisture. After reconstitution, prepare aliquots and store at -20°C.

+4°C

ALX-350-015-M250   (S)-(+)-Camptothecin   品牌 Alexis

发表于由

(S)-(+)-Camptothecin

货号： ALX-350-015-M250      产品名称： (S)-(+)-Camptothecin   品牌： Alexis 规格： 250 mg 3周到货 生化实验

(S)-(+)-Camptothecin
Potent antitumor agent
Potent antitumor agent. Inhibitor of DNA-topoisomerase I. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cells. Inhinbits Tat-mediated transactivation of HIV-1. Induces apoptosis in osteosarcoma and hepatoma cells. Suppresses nitric oxide (NO) biosynthesis.
Product Specification
Formula: C20H16N2O4
MW: 348.4
Source: Isolated from Mappia foetida Miers (Nothapodytes foetida (Wt.) Sleumer).
CAS: 7689-03-4
MI: 14: 1735
RTECS: UQ0492000
Purity: ≥98% (HPLC)
Appearance: Pale yellow powder.
Hazard: TOXIC.
Solubility: Soluble in DMSO (10mg/ml), methanol (40mg/ml), 0.1N sodium hydroxide (50mg/ml) or acetic acid; insoluble in water.
Long Term Storage: +4°C
Handling: Protect from light and moisture. After reconstitution, prepare aliquots and store at -20°C.

+4°C

ALX-350-015-G001   (S)-(+)-Camptothecin   品牌 Alexis

发表于由

(S)-(+)-Camptothecin

货号： ALX-350-015-G001      产品名称： (S)-(+)-Camptothecin   品牌： Alexis 规格： 1 g 3周到货 生化实验

(S)-(+)-Camptothecin
Potent antitumor agent
Potent antitumor agent. Inhibitor of DNA-topoisomerase I. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cells. Inhinbits Tat-mediated transactivation of HIV-1. Induces apoptosis in osteosarcoma and hepatoma cells. Suppresses nitric oxide (NO) biosynthesis.
Product Specification
Formula: C20H16N2O4
MW: 348.4
Source: Isolated from Mappia foetida Miers (Nothapodytes foetida (Wt.) Sleumer).
CAS: 7689-03-4
MI: 14: 1735
RTECS: UQ0492000
Purity: ≥98% (HPLC)
Appearance: Pale yellow powder.
Hazard: TOXIC.
Solubility: Soluble in DMSO (10mg/ml), methanol (40mg/ml), 0.1N sodium hydroxide (50mg/ml) or acetic acid; insoluble in water.
Long Term Storage: +4°C
Handling: Protect from light and moisture. After reconstitution, prepare aliquots and store at -20°C.

+4°C