标签归档：alphab

ALX-201-192-C100   alphaB-Crystallin (human) (recombinant)   品牌 Alexis

发表于由

alphaB-Crystallin (human) (recombinant)

货号： ALX-201-192-C100      产品名称： alphaB-Crystallin (human) (recombinant)   品牌： Alexis 规格： 100.micro.g 三周 生化实验

αB-Crystallin (human), (recombinant) 
Product Specification
Alternative Name: CRYAB
MW: ~20.1kDa.
Source: Produced in E. coli.
UniProt ID: P02511
Concentration: 1mg/ml
Formulation: Liquid. In 20mM TRIS-HCl, pH 7.5, containing  50mM sodium chloride and 1mM EDTA.
Purity: ≥95% (SDS-PAGE)
Long Term Storage: -20°C
Handling: Avoid freeze/thaw cycles.
Miscellaneous/General: α-crystallins are composed of two gene products: αA and αB, for acidic and basic, respectively. α-Crystallins can be
                         induced by heat shock and are members of the family of small heat shock proteins (sHSP also known as the HSP20). They
                         act as molecular chaperones and form large soluble heteroaggregates of 30-40 αA and αB subunits in a 3:1 ratio.
                        α-crystallins also have an autokinase activity and participation in the intracellular architecture. αB-crystallin is
                        expressed widely in many tissues and organs and occurs in many neurological diseases.

-20°C

BML-CA9360-0025   alphaB-Crystallin (human), pAb   品牌 Biomol

发表于由

alphaB-Crystallin (human), pAb

货号： BML-CA9360-0025      产品名称： alphaB-Crystallin (human), pAb   品牌： Biomol 规格： 25 ul 3周 生化实验

The presence of the small heat shock protein αB-crystallin in ballooned neurons, characteristic of Pick’s and Creutzfeld-Jacob disease, and in Rosenthal fibers, characteristic of Alexander’s disease, suggests a role in the aggregation and remodelling of neurofilaments in neurodegenerative disease. Both mono- and poly-ubiquitinylated conjugates of αB-crystallin have been observed in Rosenthal fibers. Phosphorylated αB-crystallin interacts with FBX4, an F-box-containing protein that is a component of the ubiquitin-protein isopeptide ligase SCF (Skp1/Cul1/F-box), implicating αB-crystallin in the ubiquitin-proteasome pathway.
Product Specification
Host:Rabbit
Immunogen:Synthetic peptide corresponding to aa 1-10 of human αB-crystallin.
UniProt ID:P02511
Application:Immunohistochemistry
Western Blot
Specificity:Recognizes human αB-crystallin
Long Term Storage:-20°C

-20°C

BML-CA9360-0100   alphaB-Crystallin (human), pAb   品牌 Biomol

发表于由

alphaB-Crystallin (human), pAb

货号： BML-CA9360-0100      产品名称： alphaB-Crystallin (human), pAb   品牌： Biomol 规格： 100 ul 3周 生化实验

The presence of the small heat shock protein αB-crystallin in ballooned neurons, characteristic of Pick’s and Creutzfeld-Jacob disease, and in Rosenthal fibers, characteristic of Alexander’s disease, suggests a role in the aggregation and remodelling of neurofilaments in neurodegenerative disease. Both mono- and poly-ubiquitinylated conjugates of αB-crystallin have been observed in Rosenthal fibers. Phosphorylated αB-crystallin interacts with FBX4, an F-box-containing protein that is a component of the ubiquitin-protein isopeptide ligase SCF (Skp1/Cul1/F-box), implicating αB-crystallin in the ubiquitin-proteasome pathway.
Product Specification
Host:Rabbit
Immunogen:Synthetic peptide corresponding to aa 1-10 of human αB-crystallin.
UniProt ID:P02511
Application:Immunohistochemistry
Western Blot
Specificity:Recognizes human αB-crystallin
Long Term Storage:-20°C

-20°C