C-REL, RBX-100UG

货号： 09-040      产品名称： C-REL, RBX-100UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-c-Rel (NFκB) Antibody
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REFERENCES
The structure of the TNFRSF13C promoter enables differential expression of BAFF-R during B cell ontogeny and terminal differentiation.
Stephen A Mihalcik,Paul M Huddleston,Xiaosheng Wu,Diane F Jelinek (2010) Journal of immunology (Baltimore, Md. : 1950).185
Divergent C-terminal transactivation domains of Rel/NF-kappa B proteins are critical determinants of their oncogenic potential in lymphocytes
Fan, Yongjun, et al (2004) Oncogene, 23:1030-42 (2004)
Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling
Chen, Xufeng, et al (2003) Cancer Res, 63:1059-66 (2003)
Species Reactivity Key Applications Host Format Antibody Type
H  ELISA, EMSA, WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-c-Rel (NFκB) Antibody
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Trade Name:
Upstate (Millipore)
Specificity:
Recognizes c-Rel
Molecular Weight:
70 kDa
Immunogen:
KLH conjugated synthetic peptide (C- MMTTSSDSMGETDNPRLLSM) corresponding to amino acids 498-517 of human c-Rel
Isotype:
IgG
Species Reactivity:
Human
Application Notes:
Immunoblot Analysis: A 0.5 g/mL dilution of this lot detected c-Rel in Raji cell lysate.
EMSA: This antibody has been shown to perform in DNA binding experiments.
ELISA: A 1:1,000 dilution of this antibody detected endogenous c-Rel in Raji cell lysate in non-denaturing conditions.
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Quality Assurance:
Routinely evaluated by immunoblot.
Purification Method:
Immunoaffinity purified
Presentation:
100 μg of immunoaffinity purified rabbit polyclonal IgG in 0.02M PBS, 0.25M sodium chloride (pH 7.6) containing 0.1% sodium azide.
Storage Conditions:
Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.
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UniProt Number:
Q04864
Entrez Gene Number:
NM_002908.2
Gene Symbol:
REL
I-Rel
C-Rel
Alternate Names:
REL
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
ELISA
Electrophoretic Mobility Shift Assay
Western Blotting
UniProt Summary:
FUNCTION: SwissProt: Q04864 # Proto-oncogene that may play a role in differentiation and lymphopoiesis. May function as a transcriptional transactivator.
SIZE: 619 amino acids; 68520 Da
SUBUNIT: Homodimer (By similarity). Interacts with NKIRAS1.
SUBCELLULAR LOCATION: Nucleus (By similarity).
SIMILARITY: SwissProt: Q04864 ## Contains 1 RHD (Rel-like) domain.
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Brand Family:
Upstate
Product Name:
Anti-c-Rel (NFκB) Antibody
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Anti -20℃