RABGDI ALPHA, RBX-100UG

货号： AB15850      产品名称： RABGDI ALPHA, RBX-100UG   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-RabGDI α (Rab GDP dissociation inhibitor α) Antibody
Species Reactivity Key Applications Host Format Antibody Type
R  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-RabGDI α (Rab GDP dissociation inhibitor α) Antibody
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Trade Name:
Chemicon (Millipore)
Specificity:
RabGDI alpha (Rab GDP dissociation inhibitor alpha). By Western blot the antibody reacts with a band at ~ 51-55 kDa on rat brain lysate.
Immunogen:
Synthetic peptide from the C-terminus of rat RabGDI alpha.
Species Reactivity:
Rat
Presentation:
Liquid in PBS with 0.1% sodium azide.
Storage Conditions:
Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.
UniProt Number:
P31150
Entrez Gene Number:
NM_001493.1
Gene Symbol:
GDI1
OPHN2
MRX48
XAP4
RABGD1A
Oligophrenin-2
GDIL
RABGDIA
XAP-4
MRX41
GDI-1
FLJ41411
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Key Applications:
Western Blotting
Entrez Gene Summary:
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
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UniProt Summary:
FUNCTION: SwissProt: P31150 # Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
SIZE: 447 amino acids; 50583 Da
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Brain; predominant in neural and sensory tissues.
DISEASE: SwissProt: P31150 # Defects in GDI1 are the cause of non-syndromic mental retardation X-linked type 41 (MRX41) [MIM:309541]; also known as MRX3. Mental retardation is characterized by significantly sub- average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. & Defects in GDI1 are the cause of non-syndromic mental retardation X-linked type 48 (MRX48) [MIM:309541]; also known as MRX3.
SIMILARITY: SwissProt: P31150 ## Belongs to the Rab GDI family.
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Brand Family:
Chemicon
Product Name:
Anti-RabGDI α (Rab GDP dissociation inhibitor α) Antibody
Antibody Type:
Polyclonal Antibody
Qty/Pk:
1
Format:
Affinity Purified
Host:
Rabbit
Applications:
This Anti-RabGDI α (Rab GDP dissociation inhibitor α) Antibody is validated for use in WB for the detection of RabGDI α (Rab GDP dissociation inhibitor α).

2-8℃