Anti-hTNF-α-hIgG1
货号: htnfa-mab1 产品名称: Anti-hTNF-α-hIgG1 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgG1
Neutralizing human IgG1 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgG1 is a neutralizing monoclonal antibody featuring the constant region of the human IgG1 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgG1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G. The neutralizing activity of this human IgG1 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgG1
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab10 Anti-hTNF-α-mIgG2a 品牌 Invivogen
Anti-hTNF-α-mIgG2a
货号: htnfa-mab10 产品名称: Anti-hTNF-α-mIgG2a 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-mIgG2a
Neutralizing murine IgG2a monoclonal antibody against human TNF-α
Anti-hTNF-α-mIgG2a is a neutralizing monoclonal antibody featuring the constant region of the murine IgG2a isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-mIgG2a was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G. The neutralizing activity of this murine IgG2a antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Mouse IgG2a
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab11 Anti-hTNF-α-mIgA 品牌 Invivogen
Anti-hTNF-α-mIgA
货号: htnfa-mab11 产品名称: Anti-hTNF-α-mIgA 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-mIgA
Neutralizing murine IgA monoclonal antibody against human TNF-α
Anti-hTNF-α-mIgA is a neutralizing monoclonal antibody featuring the constant region of the murine IgA isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-mIgA was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein L. The neutralizing activity of this murine IgA antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Mouse IgA
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab2 Anti-hTNF-α-hIgG2 品牌 Invivogen
Anti-hTNF-α-hIgG2
货号: htnfa-mab2 产品名称: Anti-hTNF-α-hIgG2 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgG2
Neutralizing human IgG2 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgG2 is a neutralizing monoclonal antibody featuring the constant region of the human IgG2 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgG2 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G. The neutralizing activity of this human IgG2 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgG2
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab3 Anti-hTNF-α-hIgG3 品牌 Invivogen
Anti-hTNF-α-hIgG3
货号: htnfa-mab3 产品名称: Anti-hTNF-α-hIgG3 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgG3
Neutralizing human IgG3 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgG3 is a neutralizing monoclonal antibody featuring the constant region of the human IgG3 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgG3 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G. The neutralizing activity of this human IgG3 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgG3
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab4 Anti-hTNF-α-hIgG4 品牌 Invivogen
Anti-hTNF-α-hIgG4
货号: htnfa-mab4 产品名称: Anti-hTNF-α-hIgG4 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgG4
Neutralizing human IgG4 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgG4 is a neutralizing monoclonal antibody featuring the constant region of the human IgG4 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgG4 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G. The neutralizing activity of this human IgG4 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
ND50 (50% neutralizing dose): ~ 2 – 5 ng/ml for 4 ng/ml human TNF-α in HEK-Blue™ TNF-α/IL-1β cells
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgG4
Formulation: 0.2 µm filtered solution in 75 mM phosphate buffer with 100 mM glycine, 5% w/v saccharose and stabilizing agents
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab5 Anti-hTNF-α-hIgM 品牌 Invivogen
Anti-hTNF-α-hIgM
货号: htnfa-mab5 产品名称: Anti-hTNF-α-hIgM 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgM
Neutralizing human IgM monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgM is a neutralizing monoclonal antibody featuring the constant region of the human IgM isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgM was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein L. The neutralizing activity of this human IgM antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgM
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab6 Anti-hTNF-α-hIgA1 品牌 Invivogen
Anti-hTNF-α-hIgA1
货号: htnfa-mab6 产品名称: Anti-hTNF-α-hIgA1 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgA1
Neutralizing human IgA1 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgA1 is a neutralizing monoclonal antibody featuring the constant region of the human IgA1 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgA1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M. The neutralizing activity of this human IgA1 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgA1
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab7 Anti-hTNF-α-hIgA2 品牌 Invivogen
Anti-hTNF-α-hIgA2
货号: htnfa-mab7 产品名称: Anti-hTNF-α-hIgA2 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgA2
Neutralizing human IgA2 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgA2 is a neutralizing monoclonal antibody featuring the constant region of the human IgA2 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgA2 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M. The neutralizing activity of this human IgA2 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgA2
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab8 Anti-hTNF-α-hIgE 品牌 Invivogen
Anti-hTNF-α-hIgE
货号: htnfa-mab8 产品名称: Anti-hTNF-α-hIgE 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-hIgE
Neutralizing human IgE monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgE is a neutralizing monoclonal antibody featuring the constant region of the human IgE isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgE was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein L. The neutralizing activity of this human IgE antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgE
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
htnfa-mab9 Anti-hTNF-α-mIgG1 品牌 Invivogen
Anti-hTNF-α-mIgG1
货号: htnfa-mab9 产品名称: Anti-hTNF-α-mIgG1 品牌: Invivogen 规格: 100 μg 二周到货 生化试验
Anti-hTNF-α-mIgG1
Neutralizing murine IgG1 monoclonal antibody against human TNF-α
Anti-hTNF-α-mIgG1 is a neutralizing monoclonal antibody featuring the constant region of the murine IgG1 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-mIgG1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with protein G. The neutralizing activity of this IgG1 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Mouse IgG1
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
porf-htnfa pORF-hTNFA 品牌 Invivogen
pORF-hTNFA
货号: porf-htnfa 产品名称: pORF-hTNFA 品牌: Invivogen 规格: 1 disk 三周到货 生化试验
TNF-α
Coding sequence in expression plasmid
Alias: TNF, TNFA, TNFSF2, DIF
Tumor Necrosis Factor Alpha
This gene is available in pUNO1 expression plasmid selectable with Blasticidin.
Human TNF-α (pUNO1-hTNFA)
Genbank: NM_000594.3
ORF Size: 702 bp
Subclone: BspHI – NheI
Mouse TNF-α (pUNO1-mTNFA)
Genbank: NM_013693.3
ORF Size: 708 bp
Subclone: BspHI – NheI
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)
puno1-htnfa pUNO1-hTNFA 品牌 Invivogen
pUNO1-hTNFA
货号: puno1-htnfa 产品名称: pUNO1-hTNFA 品牌: Invivogen 规格: 20 μg
![](http://thermofisher.jinpanbio.com/wp-content/uploads/2024/04/BZWZ.jpg)