标签： higa

hcd20-mab6   Anti-hCD20-hIgA1   品牌 Invivogen

Anti-hCD20-hIgA1

货号： hcd20-mab6      产品名称： Anti-hCD20-hIgA1   品牌： Invivogen 规格： 100 μg 二周到货 生化试验

Anti-hCD20-hIgA1
Monoclonal human IgA1 antibody against human CD20
Anti-hCD20-hIgA1 features the constant region of the human IgA1 isotype and the variable region of rituximab. Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes. Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity. Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin’s lymphoma and B-cell chronic lymphocytic leukaemia. Anti-hCD20-hIgA1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M.
Clonality: Monoclonal antibody
Specificity: Targets cells expressing human CD20
Isotype: Human IgA1

hcd20-mab7   Anti-hCD20-hIgA2   品牌 Invivogen

Anti-hCD20-hIgA2

货号： hcd20-mab7      产品名称： Anti-hCD20-hIgA2   品牌： Invivogen 规格： 100 μg 二周到货 生化试验

Anti-hCD20-hIgA2
Monoclonal human IgA2 antibody against human CD20
Anti-hCD20-hIgA2 features the constant region of the human IgA2 isotype and the variable region of rituximab. Rituximab is a mouse/human chimeric monoclonal antibody that targets the CD20 antigen found on the surface of malignant and normal B lymphocytes. Binding of rituximab to CD20 results in cell destruction through different mechanisms including direct signaling of apoptosis, complement activation and cell-mediated cytotoxicity. Rituximab has been approved by the FDA for the treatment of various lymphoid malignancies, including B-cell non-Hodgkin’s lymphoma and B-cell chronic lymphocytic leukaemia. Anti-hCD20-hIgA2 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M.
Clonality: Monoclonal antibody
Specificity: Targets cells expressing human CD20
Isotype: Human IgA2

htnfa-mab6   Anti-hTNF-α-hIgA1   品牌 Invivogen

Anti-hTNF-α-hIgA1

货号： htnfa-mab6      产品名称： Anti-hTNF-α-hIgA1   品牌： Invivogen 规格： 100 μg 二周到货 生化试验

Anti-hTNF-α-hIgA1
Neutralizing human IgA1 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgA1 is a neutralizing monoclonal antibody featuring the constant region of the human IgA1 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgA1 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M. The neutralizing activity of this human IgA1 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgA1

htnfa-mab7   Anti-hTNF-α-hIgA2   品牌 Invivogen

Anti-hTNF-α-hIgA2

货号： htnfa-mab7      产品名称： Anti-hTNF-α-hIgA2   品牌： Invivogen 规格： 100 μg 二周到货 生化试验

Anti-hTNF-α-hIgA2
Neutralizing human IgA2 monoclonal antibody against human TNF-α
Anti-hTNF-α-hIgA2 is a neutralizing monoclonal antibody featuring the constant region of the human IgA2 isotype and the variable region of adalimumab. Adalimumab is a fully human monoclonal antibody against the pro-inflammatory cytokine human tumor necrosis factor alpha (hTNF-α). Adalimumab binds to TNF-α and blocks its interaction with TNF receptors thereby downregulating the inflammatory reactions associated with autoimmune diseases, such as rheumatoid arthritis and Crohn’s disease. Anti-hTNF-α-hIgA2 was generated by recombinant DNA technology. It has been produced in CHO cells and purified by affinity chromatography with peptide M. The neutralizing activity of this human IgA2 antibody was determined using HEK-Blue™ TNF-α/IL-1β cells.
Clonality: Monoclonal antibody
Application: Neutralization of human TNF-α-induced cellular activation
Specificity: Human TNF-α
Isotype: Human IgA2