标签归档：fluorogenic

1975-5   Elastase Substrate, Fluorogenic   品牌 Biovision

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Elastase Substrate, Fluorogenic

货号： 1975-5      产品名称： Elastase Substrate, Fluorogenic   品牌： Biovision 规格： 5 mg 3周到货 生化实验

Elastase Substrate, Fluorogenic
A fluorogenic substrate for neutrophil elastase
Product Overview
Product Name: Elastase Substrate, Fluorogenic
Alternate Name/Synonyms: MeOSuc – Ala – Ala – Pro – Val – AFC; MeOSuc-AAPV-AFC
Description: A useful fluorogenic substrate for neutrophil elastase. Cleavage of this peptide by the enzyme generates a strongly fluorescent AFC that is monitored fluorometrically. λex: 380 nm; λem: 500 nm.
Peptide Sequence: N/A
Appearance: Lyophilized solid
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₃₁H₃₈N₅O₉F₃
Molecular Weight: 681.67
Purity: ≥99% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from light and moisture
SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(C(C)C)NC(=O)C3CCCN3C(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)OC
InChi: InChI=1S/C31H41N5O9/c1-16(2)27(30(42)34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,34,42)(H,35,41)
InChi Key: CMEUDEVBFFPSEI-UHFFFAOYSA-N
PubChem CID: 4083261
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.

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BML-P139-0010   OmniCathepsin Fluorogenic Substrate   品牌 Biomol

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OmniCathepsin Fluorogenic Substrate

货号： BML-P139-0010      产品名称： OmniCathepsin Fluorogenic Substrate   品牌： Biomol 规格： 10 mg 3周到货 生化实验

Product Specification
Alternative Name:Z-FR-AMC, Z-Phe-Arg-AMC
Sequence:Z-FR-AMC, Z-Phe-Arg-AMC•HCl [Z=Cbz=Benzyloxycarbonyl; AMC=7-amino-4-methylcoumarin]
Formula:C33H36N6O6 . HCl
MW:630.6
CAS:65147-22-0
Purity:99%
Long Term Storage:-20°C

-20°C

BML-P139-0050   OmniCathepsin Fluorogenic Substrate   品牌 Biomol

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OmniCathepsin Fluorogenic Substrate

货号： BML-P139-0050      产品名称： OmniCathepsin Fluorogenic Substrate   品牌： Biomol 规格： 50 mg 3周到货 生化实验

Product Specification
Alternative Name:Z-FR-AMC, Z-Phe-Arg-AMC
Sequence:Z-FR-AMC, Z-Phe-Arg-AMC•HCl [Z=Cbz=Benzyloxycarbonyl; AMC=7-amino-4-methylcoumarin]
Formula:C33H36N6O6 . HCl
MW:630.6
CAS:65147-22-0
Purity:99%
Long Term Storage:-20°C

-20°C

BML-P145-0001   Cathepsin D&E Fluorogenic Substrate   品牌 Biomol

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Cathepsin D&E Fluorogenic Substrate

货号： BML-P145-0001      产品名称： Cathepsin D&E Fluorogenic Substrate   品牌： Biomol 规格： 1 mg 3周到货 生化实验

Product Specification
Sequence:Mca-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2 [Mca= (7-methoxycoumarin-4-yl)acetyl; Dnp=dinitrophenyl]
MW:1756.0
Formulation:Lyophilized solid.
Purity:≥95%
Solubility:Soluble in DMSO (1mM) or 50% acetic acid (1mg/ml).
Long Term Storage:-20°C
Handling:Protect from light. Keep cool and dry.

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BML-P278-0100   MMP-3 fluorogenic substrate   品牌 Biomol

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MMP-3 fluorogenic substrate

货号： BML-P278-0100      产品名称： MMP-3 fluorogenic substrate   品牌： Biomol 规格： 0.1 mg 3周到货 生化实验

Product Specification
Sequence:5′-FAM-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(TQ2W)-NH2
MW:2156.9
Purity:≥90% (HPLC)
Appearance:Lyophilized orange or red solid.
Solubility:Soluble in DMSO (5mM).
Application:Useful for inhibitor screening, kinetic analysis, and cellular activity assay.
Long Term Storage:-20°C
Handling:Avoid freeze/thaw cycles of solution. Protect from light and moisture.
Miscellaneous/General: 
Highly-quenched, ultra-bright fluorogenic substrate for MMP-3 (other MMPs not tested, but likely).  5’-FAM fluorescence is thoroughly quenched by the TQ2W group until cleavage by MMP-3 separates the two moieties.  This substrate offers key advantages over other MMP-3 substrates.  1) Emission at the green end of the spectrum avoids the interference at lower wavelengths often exhibited by screening compounds, and by substances commonly found in biological samples and tissue culture medium.  2) MMP substrate peptides display poor aqueous solubility, often with Kms near or above their limits of solubility, making enzyme and inhibitor kinetics difficult.  MMP-3 Km (~0.64µM) for this substrate is below its solubility limit (~2µM in assay buffer), allowing for substrate concentrations higher than the Km, a condition generally desirable in endpoint assays.  3) In addition to the efficient binding as exhibited by low Km, this substrate is avidly cleaved by MMP-3, with a kcat/Km of ~6.5 x 107M-1sec-1.  4) The high kcat/Km and the ultra-strong fluorescence of this substrate allow for substrate concentrations much lower than the Km, a condition generally desirable in inhibitor screening/kinetics assays.

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1832-1   Proteasome Substrate, Fluorogenic   品牌 Biovision

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Proteasome Substrate, Fluorogenic

货号： 1832-1      产品名称： Proteasome Substrate, Fluorogenic   品牌： Biovision 规格： 1 mg 3周到货 生化实验

Proteasome Substrate, Fluorogenic
A proteasome substrate
Product Overview
Product Name: Proteasome Substrate, Fluorogenic
Alternate Name/Synonyms: Z-LLL-AMC; Z-Leu-Leu-Leu-AMC
Description: A fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340-360 nm; λem: 440-460 nm.
Peptide Sequence: Z-Leu-Leu-Leu-AMC
Appearance: White lyophilized powder
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₃₆H₄₈N₄O₇
Molecular Weight: 648.79
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from moisture and light
SMILES: N/A
InChi: N/A
InChi Key: N/A
PubChem CID: N/A
MDL Number: MFCD01074988
USAGE: For Research Use Only! Not For Use in Humans.

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1832-5   Proteasome Substrate, Fluorogenic   品牌 Biovision

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Proteasome Substrate, Fluorogenic

货号： 1832-5      产品名称： Proteasome Substrate, Fluorogenic   品牌： Biovision 规格： 5 mg 3周到货 生化实验

Proteasome Substrate, Fluorogenic
A proteasome substrate
Product Overview
Product Name: Proteasome Substrate, Fluorogenic
Alternate Name/Synonyms: Z-LLL-AMC; Z-Leu-Leu-Leu-AMC
Description: A fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is monitored fluorometrically. λex: 340-360 nm; λem: 440-460 nm.
Peptide Sequence: Z-Leu-Leu-Leu-AMC
Appearance: White lyophilized powder
Formulation: N/A
CAS Number: N/A
Molecular Formula: C₃₆H₄₈N₄O₇
Molecular Weight: 648.79
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from moisture and light
SMILES: N/A
InChi: N/A
InChi Key: N/A
PubChem CID: N/A
MDL Number: MFCD01074988
USAGE: For Research Use Only! Not For Use in Humans.

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