Anti-MAO-A, clone 6G11.E1

货号： MABN306      产品名称： Anti-MAO-A, clone 6G11.E1   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-MAO-A, clone 6G11.E1
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REFERENCES
Monoamine oxidase-A modulates apoptotic cell death induced by staurosporine in human neuroblastoma cells.
Fitzgerald, Julia C, et al. (2007) J. Neurochem., 103: 2189-99 (2007)
A comparative study of the expression of monoamine oxidase-A and -B mRNA and protein in non-CNS human tissues.
Sivasubramaniam, S D, et al. (2003) Cell Tissue Res., 313: 291-300 (2003)
Cellular localization of monoamine oxidase A and B in human tissues outside of the central nervous system.
Rodríguez, M J, et al. (2001) Cell Tissue Res., 304: 215-20 (2001)
Cellular localization of monoamine oxidase A and B in human tissues outside of the central nervous system.
Rodríguez, M J, et al. (2001) Cell Tissue Res., 304: 215-20 (2001)
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Species Reactivity Key Applications Host Format Antibody Type
H  WB Mouse Purified Monoclonal Antibody
Description:
Anti-MAO-A Antibody, clone 6G11.E1
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Molecular Weight:
~60 kDa observed
Immunogen:
Recombinant protein corresponding to human MAO-A.
Clone:
6G11/E1
Isotype:
IgG1κ
Background Information:
Monoamine oxidase A, also known as MAO-A, is an enzyme that is an isozyme of monoamine oxidase. It preferentially deaminates norepinephrine (noradrenaline), epinephrine (adrenaline), serotonin, and dopamine (dopamine is equally deaminated by MAO-A and MAO-B). MAO-A is inhibited by clorgiline and befloxatone. Inhibition of both MAO-A and MAO-B using a monoamine oxidase inhibitor (MAO inhibitor) is used in the treatment of clinical depression and anxiety.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human.
Application Notes:
Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect MAO-A in SH-SY5Y cells and human liver sections. (Fitzgerald, J.C., et al. (2007). Journal of Neurochemistry. 103:2189-2199).
Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect MAO-A in liver, heart, and duodenum tissues. (Rodriguez, M.J., et al. (2001). Cell Tissue Res. 304:215-220).
Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect MAO-A in kidney and lung tissues. (Sivasubramaniam, S.D., et al. (2003). Cell Tissue Res. 313:291-300).
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Control:
Human placenta tissue lysate
Quality Assurance:
Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected MAO-A in 10 µg of human placenta tissue lysate.
Purification Method:
Protein G purified
Presentation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P21397
Entrez Gene Number:
NP_000231
Gene Symbol:
MAOA
Alternate Names:
Amine oxidase [flavin-containing] A
Monoamine oxidase type A
MAO-A
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting 2-8℃