Epiregulin (EREG), human recombinant
货号: 4069-1000 产品名称: Epiregulin (EREG), human recombinant 品牌: Biovision 规格: 1 mg 3周到货 生化实验
Epiregulin (EREG), human recombinant
A ligand of EGFR, and most members of the ERBB family
Product Overview
Alternate Names / Synonyms: Epiregμlin, EREG
Gene Symbol: EREG
Accession #: O14944
Gene ID: 2069
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 0.5 mg/ml solution containing 20 mM PBS, pH 7.4 and 130 mM NaCl.
Molecular Weight: 6.0 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as dertermined by the dose-dependent stimulation of the proliferation of murine balb/3T3 cells is <2.0 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg
Reconstitution Instructions: Reconstitute in sterile water to 0.1–1 mg /ml. The solution can then further diluted to other aqueous solutions.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and Vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant human EREG produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.
-20°C
4069-25 Epiregulin (EREG), human recombinant 品牌 Biovision
Epiregulin (EREG), human recombinant
货号: 4069-25 产品名称: Epiregulin (EREG), human recombinant 品牌: Biovision 规格: 25 μg 3周到货 生化实验
Epiregulin (EREG), human recombinant
A ligand of EGFR, and most members of the ERBB family
Product Overview
Alternate Names / Synonyms: Epiregμlin, EREG
Gene Symbol: EREG
Accession #: O14944
Gene ID: 2069
Source: E. coli
Appearance: Lyophilized protein
Physical Form Description: Sterile filtered and lyophilized from 0.5 mg/ml solution containing 20 mM PBS, pH 7.4 and 130 mM NaCl.
Molecular Weight: 6.0 kDa
Purity by SDS-PAGE: ≥97%
Purity by HPLC: ≥97%
Endotoxin Level: <0.1 ng/μg
Biological Activity: The ED₅₀ as dertermined by the dose-dependent stimulation of the proliferation of murine balb/3T3 cells is <2.0 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg
Reconstitution Instructions: Reconstitute in sterile water to 0.1–1 mg /ml. The solution can then further diluted to other aqueous solutions.
Storage Temp.: -20°C
Shipping: Gel pack
Background Information: Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR, as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder, lung, kidney and colon. Epiregulin stimulates the proliferation of keratinocytes, hepatocytes, fibroblasts and Vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence. Recombinant human EREG produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa.
Handling: Centrifuge the vial prior to opening.
Usage: For Research Use Only! Not to be used in humans.
-20°C
324903-25UG Epiregulin, Human, Recombinant 品牌 Merck
Epiregulin, Human, Recombinant
货号: 324903-25UG 产品名称: Epiregulin, Human, Recombinant 品牌: Merck 规格: *** 3周到货 生化实验
Epiregulin, Human, Recombinant
Recombinant, human epiregulin consisting of amino acids 63-108 and expressed in E. coli with an N-terminal methionine. Epiregulin, expressed primarily in the placenta and macrophages, stimulates fibroblast, smooth muscle cell, and hepatocyte proliferation.
产品信息
Form Liquid
Formulation Lyophilized from 0.2 µm sterile-filtered PBS, BSA.
Biological activity ED50 = 0.125-0.75 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
Purity ≥97% by SDS-PAGE
Contaminants Endotoxin: <1.0 EU/µg protein
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling
-20°C
324904-50UG Epiregulin, Mouse, Recombinant 品牌 Merck
Epiregulin, Mouse, Recombinant
货号: 324904-50UG 产品名称: Epiregulin, Mouse, Recombinant 品牌: Merck 规格: *** 3周到货 生化实验
Epiregulin, Mouse, Recombinant
Recombinant, mouse epiregulin expressed in E. coli with an N-terminal methionine. Epiregulin is shown to inhibit epithelial tumor growth, able to stimulate growth of fibroblasts and other cell types, and has been shown to be an autocrine growth factor in human epidermal keratinocytes.
产品信息
Form Liquid
Formulation Lyophilized from 0.2 µm sterile-filtered PBS, BSA.
Biological activity ED50 = 0.3-1 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts.
Purity ≥97% by SDS-PAGE
Contaminants Endotoxin: <1.0 EU/µg protein
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling
-20°C