BML-SL105-0005   N,N-Dimethylsphingosine, D-erythro   品牌 Biomol

N,N-Dimethylsphingosine, D-erythro

货号: BML-SL105-0005      产品名称: N,N-Dimethylsphingosine, D-erythro   品牌: Biomol 规格: 5 mg 3周到货 生化实验

N,N-Dimethylsphingosine, D-erythro
Sphingosine kinase inhibitor
Replaces Prod. #: ALX-306-009
Potent and specific inhibitor of sphingosine kinase (IC50=5µM) which blocks conversion of sphingosine to sphingosine-1-phosphate (Prod. No. BML-SL140). Inhibitor of protein kinase C (PKC) which also stimulates Src-kinase. May affect expression of cell surface selectins, which in turn mediate leukocyte or tumor cell adhesion to endothelial cells and platelets. Induces apoptosis. Stereospecifically induces EGF receptor autophosphorylation producing EGF-like activity in vitro in the absence of EGF. Produced endogenously via ceramide catabolism. May be a target for neuropathic pain therapy.
Product Specification
Alternative Name: N,N-Dimethyl-D-erythro-sphingosine
Formula: C20H41NO2
MW: 327.6
Source: Synthetic.
CAS: 119567-63-4
Purity: ≥98% (TLC)
Appearance: White to off-white waxy solid or viscous oil.
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL105-0025   N,N-Dimethylsphingosine, D-erythro   品牌 Biomol

N,N-Dimethylsphingosine, D-erythro

货号: BML-SL105-0025      产品名称: N,N-Dimethylsphingosine, D-erythro   品牌: Biomol 规格: 25 mg 3周到货 生化实验

N,N-Dimethylsphingosine, D-erythro
Sphingosine kinase inhibitor
Replaces Prod. #: ALX-306-009
Potent and specific inhibitor of sphingosine kinase (IC50=5µM) which blocks conversion of sphingosine to sphingosine-1-phosphate (Prod. No. BML-SL140). Inhibitor of protein kinase C (PKC) which also stimulates Src-kinase. May affect expression of cell surface selectins, which in turn mediate leukocyte or tumor cell adhesion to endothelial cells and platelets. Induces apoptosis. Stereospecifically induces EGF receptor autophosphorylation producing EGF-like activity in vitro in the absence of EGF. Produced endogenously via ceramide catabolism. May be a target for neuropathic pain therapy.
Product Specification
Alternative Name: N,N-Dimethyl-D-erythro-sphingosine
Formula: C20H41NO2
MW: 327.6
Source: Synthetic.
CAS: 119567-63-4
Purity: ≥98% (TLC)
Appearance: White to off-white waxy solid or viscous oil.
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
Long Term Storage: -20°C

-20°C