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BML-SL100-0005   C2 Ceramide   品牌 Biomol

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C2 Ceramide

货号： BML-SL100-0005      产品名称： C2 Ceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C2 Ceramide
Cell-permeable ceramide analog
Replaces Prod. #: ALX-306-024
N-Acetylsphingosine is a biologically active, cell-permeable ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A4, activates MAP kinase and SAP kinase and induces PKCδ and ε translocation. Physiological levels of C2 ceramide, produced by the action of a PAF:sphingosine CoA-independent transacetylase, have been detected in HL-60 cells.
Product Specification
Alternative Name: N-Acetyl-D-erythro-sphingosin
Formula: C20H39NO3
MW: 341.5
CAS: 3102-57-6
Purity: ≥98% (TLC)
Appearance: White solid.
Solubility: Soluble in 100% ethanol (>25mg/ml) or DMSO (>50mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL100-0025   C2 Ceramide   品牌 Biomol

发表于由

C2 Ceramide

货号： BML-SL100-0025      产品名称： C2 Ceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C2 Ceramide
Cell-permeable ceramide analog
Replaces Prod. #: ALX-306-024
N-Acetylsphingosine is a biologically active, cell-permeable ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A4, activates MAP kinase and SAP kinase and induces PKCδ and ε translocation. Physiological levels of C2 ceramide, produced by the action of a PAF:sphingosine CoA-independent transacetylase, have been detected in HL-60 cells.
Product Specification
Alternative Name: N-Acetyl-D-erythro-sphingosin
Formula: C20H39NO3
MW: 341.5
CAS: 3102-57-6
Purity: ≥98% (TLC)
Appearance: White solid.
Solubility: Soluble in 100% ethanol (>25mg/ml) or DMSO (>50mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL101-0005   C2 Dihydroceramide   品牌 Biomol

发表于由

C2 Dihydroceramide

货号： BML-SL101-0005      产品名称： C2 Dihydroceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C2 Dihydroceramide
Negative control for C2 ceramide
C2 Dihydroceramide is inactive and may be used as a negative control for C2 ceramide.
Product Specification
Formula: C20H41NO3
MW: 343.5
CAS: 13031-64-6
Purity: ≥98% (TLC)
Appearance: White solid.
Solubility: Soluble in ethanol (5mg/mL) or DMSO (5mg/mL: dissolve in hot DMSO, then cool to RT).
Long Term Storage: -20°C

-20°C

BML-SL101-0025   C2 Dihydroceramide   品牌 Biomol

发表于由

C2 Dihydroceramide

货号： BML-SL101-0025      产品名称： C2 Dihydroceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C2 Dihydroceramide
Negative control for C2 ceramide
C2 Dihydroceramide is inactive and may be used as a negative control for C2 ceramide.
Product Specification
Formula: C20H41NO3
MW: 343.5
CAS: 13031-64-6
Purity: ≥98% (TLC)
Appearance: White solid.
Solubility: Soluble in ethanol (5mg/mL) or DMSO (5mg/mL: dissolve in hot DMSO, then cool to RT).
Long Term Storage: -20°C

-20°C

BML-SL105-0005   N,N-Dimethylsphingosine, D-erythro   品牌 Biomol

发表于由

N,N-Dimethylsphingosine, D-erythro

货号： BML-SL105-0005      产品名称： N,N-Dimethylsphingosine, D-erythro   品牌： Biomol 规格： 5 mg 3周到货 生化实验

N,N-Dimethylsphingosine, D-erythro
Sphingosine kinase inhibitor
Replaces Prod. #: ALX-306-009
Potent and specific inhibitor of sphingosine kinase (IC50=5µM) which blocks conversion of sphingosine to sphingosine-1-phosphate (Prod. No. BML-SL140). Inhibitor of protein kinase C (PKC) which also stimulates Src-kinase. May affect expression of cell surface selectins, which in turn mediate leukocyte or tumor cell adhesion to endothelial cells and platelets. Induces apoptosis. Stereospecifically induces EGF receptor autophosphorylation producing EGF-like activity in vitro in the absence of EGF. Produced endogenously via ceramide catabolism. May be a target for neuropathic pain therapy.
Product Specification
Alternative Name: N,N-Dimethyl-D-erythro-sphingosine
Formula: C20H41NO2
MW: 327.6
Source: Synthetic.
CAS: 119567-63-4
Purity: ≥98% (TLC)
Appearance: White to off-white waxy solid or viscous oil.
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL105-0025   N,N-Dimethylsphingosine, D-erythro   品牌 Biomol

发表于由

N,N-Dimethylsphingosine, D-erythro

货号： BML-SL105-0025      产品名称： N,N-Dimethylsphingosine, D-erythro   品牌： Biomol 规格： 25 mg 3周到货 生化实验

N,N-Dimethylsphingosine, D-erythro
Sphingosine kinase inhibitor
Replaces Prod. #: ALX-306-009
Potent and specific inhibitor of sphingosine kinase (IC50=5µM) which blocks conversion of sphingosine to sphingosine-1-phosphate (Prod. No. BML-SL140). Inhibitor of protein kinase C (PKC) which also stimulates Src-kinase. May affect expression of cell surface selectins, which in turn mediate leukocyte or tumor cell adhesion to endothelial cells and platelets. Induces apoptosis. Stereospecifically induces EGF receptor autophosphorylation producing EGF-like activity in vitro in the absence of EGF. Produced endogenously via ceramide catabolism. May be a target for neuropathic pain therapy.
Product Specification
Alternative Name: N,N-Dimethyl-D-erythro-sphingosine
Formula: C20H41NO2
MW: 327.6
Source: Synthetic.
CAS: 119567-63-4
Purity: ≥98% (TLC)
Appearance: White to off-white waxy solid or viscous oil.
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL110-0005   C6 Ceramide   品牌 Biomol

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C6 Ceramide

货号： BML-SL110-0005      产品名称： C6 Ceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C6 Ceramide
Cell-permeable ceramide analog
Replaces Prod. #: ALX-303-003
A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.
Product Specification
Alternative Name: N-Hexanoyl-D-erythro-sphingosine
Formula: C24H47NO3
MW: 397.7
CAS: 124753-97-5
Purity: ≥98% (TLC)
Appearance: White waxy solid.
Solubility: Soluble in 100% ethanol (>25mg/ml) and DMSO (>50mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL110-0025   C6 Ceramide   品牌 Biomol

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C6 Ceramide

货号： BML-SL110-0025      产品名称： C6 Ceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C6 Ceramide
Cell-permeable ceramide analog
Replaces Prod. #: ALX-303-003
A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.
Product Specification
Alternative Name: N-Hexanoyl-D-erythro-sphingosine
Formula: C24H47NO3
MW: 397.7
CAS: 124753-97-5
Purity: ≥98% (TLC)
Appearance: White waxy solid.
Solubility: Soluble in 100% ethanol (>25mg/ml) and DMSO (>50mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL111-0005   C6 Dihydroceramide   品牌 Biomol

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C6 Dihydroceramide

货号： BML-SL111-0005      产品名称： C6 Dihydroceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C6 Dihydroceramide
Negative control for C6 ceramide
C6 Dihydroceramide is inactive and may be used as a negative control for C6 ceramide.
Product Specification
CAS: 171039-13-7
Purity: 98%
Long Term Storage: -20°C

-20°C

BML-SL111-0025   C6 Dihydroceramide   品牌 Biomol

发表于由

C6 Dihydroceramide

货号： BML-SL111-0025      产品名称： C6 Dihydroceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C6 Dihydroceramide
Negative control for C6 ceramide
C6 Dihydroceramide is inactive and may be used as a negative control for C6 ceramide.
Product Specification
CAS: 171039-13-7
Purity: 98%
Long Term Storage: -20°C

-20°C

BML-SL112-0005   C8 Ceramide   品牌 Biomol

发表于由

C8 Ceramide

货号： BML-SL112-0005      产品名称： C8 Ceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C8 Ceramide
Ceramide-activated protein kinase activator
Replaces Prod. #: ALX-306-013
A biologically active, cell-permeable, but nonphysiologic ceramide analog. It induces phosphorylation of epidermal growth factor receptor on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase and induces apoptosis.
Product Specification
Formula: C26H51NO3
MW: 425.7
CAS: 74713-59-0
Purity: ≥98% (TLC)
Appearance: White waxy solid.
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml)
Long Term Storage: -20°C

-20°C

BML-SL112-0025   C8 Ceramide   品牌 Biomol

发表于由

C8 Ceramide

货号： BML-SL112-0025      产品名称： C8 Ceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C8 Ceramide
Ceramide-activated protein kinase activator
Replaces Prod. #: ALX-306-013
A biologically active, cell-permeable, but nonphysiologic ceramide analog. It induces phosphorylation of epidermal growth factor receptor on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase and induces apoptosis.
Product Specification
Formula: C26H51NO3
MW: 425.7
CAS: 74713-59-0
Purity: ≥98% (TLC)
Appearance: White waxy solid.
Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (25mg/ml)
Long Term Storage: -20°C

-20°C

BML-SL113-0005   C8-Dihydroceramide   品牌 Biomol

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C8-Dihydroceramide

货号： BML-SL113-0005      产品名称： C8-Dihydroceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C8-Dihydroceramide
Negative control for C8 ceramide
C8 Dihydroceramide is inactive and may be used as a negative control for C8 ceramide.
Product Specification
Formula: C26H53NO3
MW: 427.7
CAS: 145774-33-0
Purity: ≥98% (TLC)
Appearance: White waxy solid.
Solubility: Soluble in DMF (25 mg/ml), DMSO (5 mg/ml) or ethanol (10mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL113-0025   C8-Dihydroceramide   品牌 Biomol

发表于由

C8-Dihydroceramide

货号： BML-SL113-0025      产品名称： C8-Dihydroceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C8-Dihydroceramide
Negative control for C8 ceramide
C8 Dihydroceramide is inactive and may be used as a negative control for C8 ceramide.
Product Specification
Formula: C26H53NO3
MW: 427.7
CAS: 145774-33-0
Purity: ≥98% (TLC)
Appearance: White waxy solid.
Solubility: Soluble in DMF (25 mg/ml), DMSO (5 mg/ml) or ethanol (10mg/ml).
Long Term Storage: -20°C

-20°C

BML-SL115-0005   C16 Ceramide   品牌 Biomol

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C16 Ceramide

货号： BML-SL115-0005      产品名称： C16 Ceramide   品牌： Biomol 规格： 5 mg 3周到货 生化实验

C16 Ceramide
Endogenous ceramide
An abundant molecular species of endogenous ceramide. It induces phosphorylation of epidermal growth factor receptor on Thr669 in A-431 cells by stimulation of ceramide-activated protein kinase and activates NF-κB at concentrations as low as 50 nM. Activates PKCζ.
Product Specification
Alternative Name: N-Palmitoylsphingosine, D-erythro, N-Hexadecanoyl-D-erythro-sphingosine, N-Palmitoyl ceramide
Formula: C34H67NO3
MW: 537.9
CAS: 24696-26-2
Purity: ≥98% (TLC)
Appearance: Waxy solid.
Solubility: Soluble in 100% ethanol (5mg/ml warm).
Long Term Storage: -20°C

-20°C

BML-SL115-0025   C16 Ceramide   品牌 Biomol

发表于由

C16 Ceramide

货号： BML-SL115-0025      产品名称： C16 Ceramide   品牌： Biomol 规格： 25 mg 3周到货 生化实验

C16 Ceramide
Endogenous ceramide
An abundant molecular species of endogenous ceramide. It induces phosphorylation of epidermal growth factor receptor on Thr669 in A-431 cells by stimulation of ceramide-activated protein kinase and activates NF-κB at concentrations as low as 50 nM. Activates PKCζ.
Product Specification
Alternative Name: N-Palmitoylsphingosine, D-erythro, N-Hexadecanoyl-D-erythro-sphingosine, N-Palmitoyl ceramide
Formula: C34H67NO3
MW: 537.9
CAS: 24696-26-2
Purity: ≥98% (TLC)
Appearance: Waxy solid.
Solubility: Soluble in 100% ethanol (5mg/ml warm).
Long Term Storage: -20°C

-20°C

BML-SL125-0010   Dihydrosphingosine, D-erythro   品牌 Biomol

发表于由

Dihydrosphingosine, D-erythro

货号： BML-SL125-0010      产品名称： Dihydrosphingosine, D-erythro   品牌： Biomol 规格： 10 mg 3周到货 生化实验

Dihydrosphingosine, D-erythro
Sphingosine precursor
Biosynthetic precursor of sphingosine. Inhibitor of protein kinase C (PKC). Blocks phospholipases A2 (PLA2) and the D-sphingosine precursor.
Product Specification
Alternative Name: D-erythro-Sphingosine, Dihydro-, Sphinganine
Formula: C18H39NO2
MW: 301.5
CAS: 764-22-7
Purity: ≥98% (TLC)
Appearance: White to off-white solid.
Solubility: Soluble in 100% ethanol (25mg/ml, warm) or DMSO (25mg/ml, warm).
Long Term Storage: -20°C

-20°C

BML-SL125-0050   Dihydrosphingosine, D-erythro   品牌 Biomol

发表于由

Dihydrosphingosine, D-erythro

货号： BML-SL125-0050      产品名称： Dihydrosphingosine, D-erythro   品牌： Biomol 规格： 50 mg 3周到货 生化实验

Dihydrosphingosine, D-erythro
Sphingosine precursor
Biosynthetic precursor of sphingosine. Inhibitor of protein kinase C (PKC). Blocks phospholipases A2 (PLA2) and the D-sphingosine precursor.
Product Specification
Alternative Name: D-erythro-Sphingosine, Dihydro-, Sphinganine
Formula: C18H39NO2
MW: 301.5
CAS: 764-22-7
Purity: ≥98% (TLC)
Appearance: White to off-white solid.
Solubility: Soluble in 100% ethanol (25mg/ml, warm) or DMSO (25mg/ml, warm).
Long Term Storage: -20°C

-20°C

BML-SL130-0001   3-Ketosphingosine   品牌 Biomol

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3-Ketosphingosine

货号： BML-SL130-0001      产品名称： 3-Ketosphingosine   品牌： Biomol 规格： 1 mg 3周到货 生化实验

3-Ketosphingosine
Useful precursor for radiolabeled sphingosine
A useful precursor for the preparation of radiolabeled sphingosine. A saturated form of 3-ketosphingosine, or 3-ketosphinganine is the first intermediate in the biosynthesis of sphingosine.
Product Specification
Formula: C18H35NO2 . HCl
MW: 339.9
CAS: 19767-16-9
Purity: ≥95% (TLC)
Identity:Determined by NMR.
Appearance:White solid.
Solubility:Soluble in DMSO (>25 mg/ml) or ethanol (>25 mg/ml).
Long Term Storage:-20°C

-20°C